Results 271 to 280 of about 346,940 (303)
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Estimation of acute oral toxicity in rates by determination of the approximate lethal dose rather than the LD50

Journal of Applied Toxicology, 1986
AbstractThe approximiate lethal dose (ALD) to rats following oral administration of nine chemicals was determined. The ALD (lowest dose at which death was produced) for each chemical was used to define the general order of toxicity as being either extremely, highly, moderately, slightly, or practically non‐toxic.
G L, Kennedy, R L, Ferenz, B A, Burgess
openaire   +2 more sources

[Are acute toxicity testing and the three Rs rule reconcilable? Example of the lethal dose 50 determination].

Annales pharmaceutiques francaises, 2004
Toxicity assessment and demonstration of innocuousness of chemical compounds have been part of the research studies conducted in the fields of pharmacy, agriculture and chemical industry for years. Acute systemic toxicity studies are an important element of the safety evaluation.
Fr, Dorandeu, G, Lallement
openaire   +1 more source

Immunomodulatory Effects of Cold Stress on Mice Infected Intraperitoneally with a 50% Lethal Dose of <i>Toxoplasma gondii</i>

Neuroimmunomodulation, 2001
Cofactors such as stress have been suspected to play a role in the susceptibility to opportunistic infections. <i>Toxoplasma gondii </i>is one of the major opportunistic infectious agents in immunocompromised individuals, and infection can be modulated by external factors such as stress.
Hernan Aviles, Fernando P. Monroy
openaire   +1 more source

VI. The 50 Per Cent Lethal Dose for the Chick Embryo

The British Journal of Radiology, 1957
John Boland, F. W. Tranter
openaire   +1 more source

Investigation on Median Lethal Dose (LD(50)) and Hypoglycemic Effect of Thymus fallax F. Leaves Essential Oil

2009
We aimed to investigate median lethal dose (LD(50)) and hypoglycemic effect of Thymus fallax F. leaves essential oil (TF) on healthy and diabetic mice. TF, glibenclamide (as a reference group) and isotonic saline solution (ISS) (control group) were administrated to the healthy and alloxan-induced diabetic mice.
Oezturk, Mustafa   +2 more
openaire   +1 more source

Studies on mutagenesis in garlic using chemical mutagens to determine lethal dose (LD50) and create variability

Indian Journal of Horticulture, 2015
Vijay Mahajan   +3 more
openaire   +1 more source

The Lethal Phenotype of Cancer: The Molecular Basis of Death Due to Malignancy

Ca-A Cancer Journal for Clinicians, 2007
Arul M Chinnaiyan   +2 more
exaly  

Poly(ADP-Ribose) polymerase (PARP) inhibitors: Exploiting a synthetic lethal strategy in the clinic

Ca-A Cancer Journal for Clinicians, 2011
Timothy A Yap, Johann Sebastian de Bono
exaly  

[ON THE DEPENDENCE OF THE MEDIAN LETHAL DOSE (LD-50) ON EXOGENOUS FACTORS].

Archives internationales de pharmacodynamie et de therapie, 1996
O, SELISKO, G, HENTSCHEL, H, ACKERMANN
openaire   +1 more source

Issues with implementing a high‐quality lung cancer screening program

Ca-A Cancer Journal for Clinicians, 2014
James L Mulshine
exaly  

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