Designed Azolopyridinium Salts Block Protective Antigen Pores In Vitro and Protect Cells from Anthrax Toxin [PDF]
, 2013 Background:Several intracellular acting bacterial protein toxins of the AB-type, which are known to enter cells by endocytosis, are shown to produce channels.
Barth, Holger +24 more
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Lethally high ROS levels thwart resistance [PDF]
Nature Reviews Cancer, 2018 Wang, Leite de Oliveira et al. show that BRAFV600E-mutant melanomas that are resistant to BRAF and MEK inhibitors are vulnerable to increased levels of reactive oxygen species and that this can be exploited therapeutically using a histone deacetylase inhibitor.
openaire +2 more sources
Metabolic Regulation of the Epigenome Drives Lethal Infantile Ependymoma
Cell, 2020 SUMMARY Posterior fossa A (PFA) ependymomas are lethal malignancies of the hindbrain in infants and toddlers. Lacking highly recurrent somatic mutations, PFAs are proposed as an epigenetically driven tumor for which model systems are lacking.
K. Michealraj +65 more
semanticscholar +1 more source
THE ROLE OF NON-LETHAL WEAPONS IN PUBLIC SECURITY [PDF]
Revija za kriminologiju i krivično pravo, 2022 After World War II, “human rights” became a very vital issue all over the world, and with the publication of the Universal Declaration of Human Rights by the United Nations at the end of 1948, the subject gained an international status.
Erdem Eren Demir +2 more
doaj +1 more source
Perceptions of alien plants and animals and acceptance of control methods among different societal groups [PDF]
NeoBiota, 2020 Biological invasions are a widespread phenomenon and cause substantial impacts on the natural environment and human livelihoods. Thus, the European Union (EU) recently adopted Regulation No 1143/2014 to limit the negative impacts of invasive alien ...
Raphael Höbart +2 more
doaj +3 more sources
Frontiers in Psychology, 2022 Under conditions of physiological stress, officers are sometimes required to make split-second life-or-death decisions, where deficits in performance can have tragic outcomes, including serious injury or death and strained police–community relations. The
Simon Baldwin +9 more
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Insects, 2019 Insects play an important role in the stability of ecosystems by fulfilling key functions such as pollination and nutrient cycling, as well as acting as prey for amphibians, reptiles, birds and mammals.
Merle T. Bartling +2 more
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Effect of Ziziphora clinopodioides Essential Oil Stress on Viability of Lactobacillus acidophilus and Bifidobacterium bifidum Microencapsulated with Alginate-Chitosan and Physicochemical and Sensory Properties of Probiotic Yoghurt [PDF]
Iranian Journal of Veterinary Medicine, 2021 BACKGROUND: The probiotics must be alive in sufficient numbers and one of the main stress factors that probiotic strains should tolerate is food preservatives, like herbal essential oils (EOs).
Nafise Alighazi +3 more
doaj +1 more source
Lethal and non-lethal effects of trawling on the benthic invertebrate food web
, 2020 The pulse trawl is presented as an alternative for the traditional tickler chain beam trawl. The beam trawl has a direct lethal effect on the benthic community, which is much less for the pulse trawl. However, the pulse trawl, due to its electrical field
van de Wolfshaar, K.E. +4 more
core +1 more source
The effects of network neighbours on protein evolution. [PDF]
PLoS ONE, 2011 Interacting proteins may often experience similar selection pressures. Thus, we may expect that neighbouring proteins in biological interaction networks evolve at similar rates.
Guang-Zhong Wang, Martin J Lercher
doaj +1 more source