Results 101 to 110 of about 316,536 (262)
FEBS Open Bio, EarlyView.NF90–NF45 functions as a negative regulator of methyltransferase‐like 3/14 (METTL3/14)‐mediated N6‐methyladenosine (m6A) modification on primary microRNAs (pri‐miRNAs). NF90–NF45 binds to anti‐oncogenic pri‐miRNAs and inhibits their m6A modification, thereby suppressing the biogenesis of anti‐oncogenic miRNAs.
Takuma Higuchi +6 more
wiley +1 more source
Mineta Transportation Institute Says Subways Are Still in Terrorists’ Sights [PDF]
, 2014 The FBI arrested a California National Guard reservist on March 17 as he headed for the Canadian border on his way to Syria. Once in Syria, Nicholas Michael Teausant, who is also a student at San Joaquin Delta Community College in Stockton CA, planned to
Butterworth, Bruce R., Jenkins, Brian M.
core +1 more source
FEBS Open Bio, EarlyView.dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon +6 more
wiley +1 more source
Microbiology SpectrumKlebsiella pneumoniae is a significant healthcare-associated pathogen, notable for its diverse virulence and antibiotic resistance profiles. This study aimed to characterize the genotypic and phenotypic diversity of K.
María Guembe +9 more
doaj +1 more source
THE EFFECT OF LITHIUM ON ACUTE TOXICITY OF CARBAMAZEPINE IN MICE [PDF]
Acta Medica Iranica, 1997 The effects of chronic administration of lithium, on acute toxicity of carbamazepine (CBZ) in mate albino mice was studied and the LD50 values were determined from dose-probit curves.
M. Samini., A.R. Dehpour, K. Hajinabi
doaj
PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines
FEBS Open Bio, EarlyView.Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart +7 more
wiley +1 more source
COMPARATIVE CHARACTERISTICS OF EPIDEMIC SEASONS OF INFLUENZA 2015 - 2016 AND 2009 - 2010
Журнал микробиологии, эпидемиологии и иммунобиологии, 2017 Aim. Analyze epidemiologic and clinical features of influenza epidemic seasons 2009 - 2010 and 2015 - 2016. Materials and methods. Forms of federal state statistic observation No.
T. V. Ykovleva +4 more
doaj +1 more source
FEBS Open Bio, EarlyView.Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel +8 more
wiley +1 more source
Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment
Aging and Cancer, EarlyView.Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey +12 more
wiley +1 more source
Immune Checkpoint Inhibitor–Related Myositis and Associated Triad Overlap Syndrome
Arthritis Care &Research, EarlyView.Objective Immune checkpoint inhibitor (ICI) myositis is a rare but a highly morbid condition, particularly with the ICI myositis triad syndrome of myositis, myocarditis, and myasthenia gravis. We report the clinical characteristics of ICI myositis and all‐cause mortality in these patients.
Selene Rubino +9 more
wiley +1 more source