Results 51 to 60 of about 4,225,603 (282)
In this explorative biomarker analysis, we assessed serial sampling of circulating tumor cells (CTCs) with CellSearch in two randomized trials testing immune checkpoint inhibitors (ICIs) in metastatic breast cancer. Our data demonstrate a prognostic potential of CTCs, most apparent 4 weeks into ICI therapy.
Nikolai Kragøe Andresen+13 more
wiley +1 more source
The project P. S. Post Scriptum (2012–2017) was aimed at the collection, edition, and analysis of Spanish and Portuguese private letters from the 16th to the early 19th century.
Ulrike Henny-Krahmer
doaj +1 more source
Cell‐free and extracellular vesicle microRNAs with clinical utility for solid tumors
Cell‐free microRNAs (cfmiRs) are small‐RNA circulating molecules detectable in almost all body biofluids. Innovative technologies have improved the application of cfmiRs to oncology, with a focus on clinical needs for different solid tumors, but with emphasis on diagnosis, prognosis, cancer recurrence, as well as treatment monitoring.
Yoshinori Hayashi+6 more
wiley +1 more source
The Discourse of Infatuation in John Keats’s Letters and Poems to Fanny Brawne
Seen from the vantage point of the Victorian sensibility, John Keats’s letters to Fanny Brawne transgress the norms of respectability, being too personal, too passionate and too direct.
Malgorzata Łuczyńska-Hołdys
doaj
Der Zürcher Sommer 1968: Die digitale Edition
Der Zürcher Sommer 1968 is a digital edition of the events in the late summer 1968. The edition is hosted by the University of Zurich. For the first time, various documents such as newspaper articles, wall newspapers, protocols of interrogation and other
Friederike Wein
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Necessity or Unnecessary of writing Gemination in the Persian language [PDF]
The plenty and variety of the Geminated Words indicates that certainly Gemination appears in the speech and speakers of the Persian language know this. The obvious reason is that Persian speakers whether young or old produce Gemination systematically and
آسیه ذبیح نیا عمران
doaj +1 more source
This study simultaneously investigated circulating tumor cells (CTCs) and exosomes from small‐cell lung cancer (SCLC) patients. The elevated expression of JUNB and CXCR4 in CTCs was a poor prognostic factor for SCLC patients, whereas exosomal overexpression of these biomarkers revealed a high discrimination ability of patients from healthy individuals,
Dimitrios Papakonstantinou+13 more
wiley +1 more source
MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin+14 more
wiley +1 more source
Presurgery 72‐h fasting in GB patients leads to adaptations of plasma lipids and polar metabolites. Fasting reduces lysophosphatidylcholines and increases free fatty acids, shifts triglycerides toward long‐chain TGs and increases branched‐chain amino acids, alpha aminobutyric acid, and uric acid.
Iris Divé+7 more
wiley +1 more source
Sense-Making and Map-Making: War Letters as Personal Geographies
Structured in three parts, this article will briefly review David Herman’s idea of “spatial reference” in narrative, particularly in epistolary form, and explain the research method used in this project; introduce military geographies and demonstrate how
Christina Knopf
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