Results 211 to 220 of about 639,233 (341)

Reversible Lichtinduzierte Oligomerisierung von Arabidopsis‑Cryptochrom 1 und Antagonismus durch BIC1: Einblicke durch Zeitaufgelöste Native Massenspektrometrie

open access: yesAngewandte Chemie, EarlyView.
Mittels zeitaufgelöster nativer Massenspektrometrie wird der blaulichtabhängige kinetische Mechanismus der Oligomerisierung von Arabidopsis CRY1 aufgedeckt. Die Oligomerisierung verläuft sequenziell von Monomeren über Dimere zu Tetrameren. Während ATP die Assemblierung fördert, inhibiert BIC1 die Tetramerbildung und dissoziiert diese unabhängig von ...
Alicia Just   +8 more
wiley   +1 more source

Metabolic adaptation of skeletal muscle to hyperammonemia drives the beneficial effects of l-leucine in cirrhosis.

open access: yesJournal of Hepatology, 2016
G. Davuluri   +7 more
semanticscholar   +1 more source

The Leucine-mTOR-Autophagy Axis in Granulosa Cells Mediates Circadian Disruption-Induced Anovulation. [PDF]

open access: yesInt J Biol Sci
He R   +14 more
europepmc   +1 more source

Time‐Resolved Native Mass Spectrometry Reveals Reversible Light‐Driven Oligomerization of Arabidopsis Cryptochrome 1 and Its Antagonism by BIC1

open access: yesAngewandte Chemie International Edition, EarlyView.
Time‐resolved native mass spectrometry uncovers the blue‐light‐dependent kinetic mechanism of Arabidopsis CRY1 oligomerization, proceeding sequentially from monomers to dimers and tetramers. ATP promotes assembly, whereas BIC1 actively blocks and disassembles tetramers independent of light, providing mechanistic insight into the regulation of ...
Alicia Just   +8 more
wiley   +1 more source

Leucine supplementation does not attenuate the decline in daily muscle protein synthesis rates or preserve leg muscle mass during leg immobilization in young or older adults: a double-blind randomized trial. [PDF]

open access: yesAm J Clin Nutr
Churchward-Venne TA   +10 more
europepmc   +1 more source

Dietary Mannan‐Rich Fractions Attenuate Weaning Stress in Piglets via Modulating Gut Microbiota and TLR5/NF‐κB Signaling

open access: yesAnimal Research and One Health, EarlyView.
This study aimed to investigate the potential of a mannan‐rich fraction (MRF) as a dietary intervention to alleviate weaning stress in piglets. Our results revealed that MRF could alleviate weaning stress by modulating the gut microbiota and the TLR5/NF‐κB signaling pathway, offering a novel and sustainable alternative to antibiotic use in swine ...
Yutong Lu   +8 more
wiley   +1 more source

Methyl-specific NMR of therapeutic antibodies: cost-effective isotopic labeling strategies in CHO cells for high-resolution structural characterization. [PDF]

open access: yesJ Biomol NMR
Awad R   +12 more
europepmc   +1 more source

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