Results 1 to 10 of about 134,049 (309)
Frontiers in Immunology, 2022 Inflammatory bowel disease (namely, colitis) severely impairs human health. Isoleucine is reported to regulate immune function (such as the production of immunoreactive substances).
Xiangbing Mao +51 more
doaj +2 more sources
The adverse metabolic effects of branched-chain amino acids are mediated by isoleucine and valine
Cell Metabolism, 2021 SUMMARY Low protein diets promote metabolic health in rodents and humans, and the benefits of low protein diets are recapitulated by specifically reducing dietary levels of the three branched-chain amino acids (BCAAs), leucine, isoleucine, and valine ...
Ildikó Kasza +2 more
exaly +2 more sources
Frontiers in Immunology, 2018 Rotavirus (RV) infection is one of the main pathogenic causes of severe gastroenteritis and diarrhea in infants and young animals. This study aimed to determine how dietary l-isoleucine supplementation improves the growth performance and immune response ...
Xiangbing Mao +23 more
doaj +2 more sources
Effects of dietary L-isoleucine on laying performance and immunomodulation of laying hens
Poultry Science, 2016 Isoleucine may be a limiting amino acid for laying hens fed diets with a lowered protein level. An experiment was conducted to examine laying performance and the immune function of laying hens provided diets varying in digestible isoleucine levels during
X T Zou, X Y Dong, X T Zou
exaly +2 more sources
Poultry Science, 2021 : Three experiments (Exp) were conducted to determine optimal digestible Ile to Lys ratios for male Yield Plus × Ross 708 broilers from approximately 1.0 to 4.0 kg BW.
T.L. Wise +4 more
doaj +1 more source
bioRxiv, 2022 Low protein (LP) diets promote health and longevity in diverse species. Although the precise components of an LP diet that mediate its beneficial effects have not been defined, reducing dietary levels of the three branched-chain amino acids (BCAAs ...
Cara L. Green +18 more
semanticscholar +1 more source
Frontiers in Nutrition, 2022 BackgroundPrevious studies showed conflicting evidence on the association between the intake of dietary branched-chain amino acid (BCAA) and the risk of cardiovascular disease (CVD). However, this relationship has not been studied in patients with type 2
Lu Zheng +15 more
doaj +1 more source
High dose isoleucine stabilizes nuclear PTEN to suppress the proliferation of lung cancer
Discover Oncology, 2023 Purpose Cancer cells require a supply of amino acids, particularly essential amino acids such as branched-chain amino acids (BCAAs, i.e., valine, leucine, and isoleucine), to meet the increased nutrient demands of malignant tumors.
Haiqing Wang +16 more
semanticscholar +1 more source
Gastroenterology, 2021 Background and Aims Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is associated with altered gut microbiota composition. Phylogenetic groups of gut bacteria involved in the metabolism
Fen Zhang +15 more
semanticscholar +1 more source
Molecules and Cells, 2021 SUMMARY: Quantitative subcellular metabolomic measurements can explain the roles of metabolites in cellular processes, but are subject to multiple confounding factors.
Sophie Trefely +21 more
semanticscholar +1 more source