Results 1 to 10 of about 101,388 (214)
Isoleucine-to-valine substitutions support cellular physiology during isoleucine deprivation
Nucleic Acids ResearchAbstract Aminoacyl-tRNA synthetases (ARSs) couple tRNAs with their corresponding amino acids. While ARSs can bind structurally similar amino acids, extreme specificity is ensured by subsequent editing activity. Yet, we found that upon isoleucine (I) restriction, healthy fibroblasts consistently incorporated valine (V) into proteins at ...
Holger Rehmann +2 more
exaly +6 more sources
Isoleucine Hydroxamate, an Isoleucine Antagonist [PDF]
Journal of Bacteriology, 1971 Isoleucine hydroxamate (Ile·Hdx) was found to inhibit the growth of Serratia marcescens and to antagonize isoleucine. At a low concentration of Ile·Hdx, at which the growth of the wild strain was completely inhibited, the growth of an isoleucine auxotroph was not inhibited in the medium containing a limiting amount ...
M, Kisumi +3 more
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TFIIIR Is an Isoleucine tRNA [PDF]
Molecular and Cellular Biology, 1994 Promoter-specific transcription by silkworm RNA polymerase III is dependent on several transcription factors (TFs) in addition to the polymerase itself. The activities present in silk gland nuclear extracts that are necessary to reconstitute transcription from class III genes in vitro have been resolved into several partially purified components. These
H M, Dunstan, L S, Young, K U, Sprague
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The Journal of Physical Chemistry B, 2020 A detailed investigation of the structural and conformational properties of alanine-isoleucine (Ala-Ile) and isoleucine-isoleucine (Ile-Ile) dipeptides is presented in water and in methanol solvents. We propose a consistent combination of complementary simulation and experimental methods, covering a broad range of length and time scales, from the very ...
Anastassia N. Rissanou +4 more
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Anomalies in the refinement of isoleucine [PDF]
Acta Crystallographica Section D Biological Crystallography, 2014 A study of isoleucines in protein structures solved using X-ray crystallography revealed a series of systematic trends for the two side-chain torsion angles χ1and χ2dependent on the resolution, secondary structure and refinement software used. The average torsion angles for the nine rotamers were similar in high-resolution structures solved using ...
Berntsen, K.R.M., Vriend, G.
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NMR-based assignment of isoleucinevs.allo-isoleucine stereochemistry [PDF]
Organic & Biomolecular Chemistry, 2017 A simple1H and13C NMR spectrometric analysis is demonstrated that permits differentiation of isoleucine andallo-isoleucine residues by inspection of the chemical shift and coupling constants of the signals associated with the proton and carbon at the α-stereocentre.
Zoe J. Anderson +6 more
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Leucine and isoleucine requirements of the kitten [PDF]
British Journal of Nutrition, 1984 1. In separate experiments the isoleucine and leucine requirements of the kitten were determined on the basis of growth and nitrogen retention. The dietary concentrations of isoleucine tested were (g/kg diet) 1.4, 2.2, 3.0, 3.8, 4.6 and 9.0 with adequate (12.0 g/kg diet) leucine.
D M, Hargrove, Q R, Rogers, J G, Morris
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tRNA-isoleucine-tryptophan composite gene [PDF]
Biochemical and Biophysical Research Communications, 2006 15 pages, 3 ...
Ghosh, Zhumur +5 more
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Nippon kagaku zassi, 1957 イソロイシンは従来他の脂肪属アミノ酸と同様な方法で合成されているが,著者らは実用的な目的を以て最近安価に入手し得るメチルエチルケトンからイソロィシンを合成することを二方法,すなわち中間体としてα一ニトローβ 一メチルーβ 一エチルアクリル酸エチルを経る方法と,α 一プロムーβ一メチルバレリアン酸を経る方法とによって試み,かつ得られたイソロイシンについて,イソロイシンとアロイソロィシンの混合比を関の方法により定量した。
Yutaka Mori +2 more
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A " NEW " DISORDER OF ISOLEUCINE CATABOLISM
The Lancet, 1971 A disorder of isoleucine catabolism was found in a child with intermittent metabolic acidosis. The block occurs at the stage of propionate synthesis, and two intermediates--alpha-methylacetoacetate and alpha-methyl-beta-hydroxybutyrate--accumulate. The condition is apparently inherited.
R S, Daum +3 more
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