Results 11 to 20 of about 122,784 (300)

Isoleucine-to-valine substitutions support cellular physiology during isoleucine deprivation [PDF]

open access: yesNucleic Acids Research
Abstract Aminoacyl-tRNA synthetases (ARSs) couple tRNAs with their corresponding amino acids. While ARSs can bind structurally similar amino acids, extreme specificity is ensured by subsequent editing activity. Yet, we found that upon isoleucine (I) restriction, healthy fibroblasts consistently incorporated valine (V) into proteins at ...
Sabine Fuchs   +2 more
exaly   +5 more sources

NMR-based assignment of isoleucine vs . allo -isoleucine stereochemistry [PDF]

open access: yesOrganic & Biomolecular Chemistry, 2017
A simple 1 H and 13 C NMR spectrometric analysis is demonstrated that permits differentiation of isoleucine and allo -isoleucine residues by inspection of the chemical shift and coupling constants of the signals ...
Zoe J. Anderson   +6 more
openaire   +5 more sources

Systemic energy metabolism changes in patients with heart failure receiving specific oral nutritional supplements in combination with Mediterranean diet [PDF]

open access: yesFrontiers in Nutrition
BackgroundHeart failure (HF) is associated with disease-related malnutrition, all of which contribute to impaired functional capacity and adverse outcomes.
Aura D. Herrera-Martínez   +11 more
doaj   +2 more sources

Real-Time Optical Detection of Isoleucine in Living Cells through a Genetically-Encoded Nanosensor

open access: yesSensors, 2019
Isoleucine is one of the branched chain amino acids that plays a major role in the energy metabolism of human beings and animals. However, detailed investigation of specific receptors for isoleucine has not been carried out because of the non ...
Shruti Singh   +5 more
doaj   +2 more sources

l-Isoleucine Administration Alleviates DSS-Induced Colitis by Regulating TLR4/MyD88/NF-κB Pathway in Rats

open access: yesFrontiers in Immunology, 2022
Inflammatory bowel disease (namely, colitis) severely impairs human health. Isoleucine is reported to regulate immune function (such as the production of immunoreactive substances).
Xiangbing Mao   +51 more
doaj   +1 more source

Determination of the optimum digestible isoleucine to lysine ratios for male Yield Plus × Ross 708 broilers between 1.0 and 4.0 kg body weight utilizing growth performance and carcass characteristics1

open access: yesPoultry Science, 2021
: Three experiments (Exp) were conducted to determine optimal digestible Ile to Lys ratios for male Yield Plus × Ross 708 broilers from approximately 1.0 to 4.0 kg BW.
T.L. Wise   +4 more
doaj   +1 more source

The association between dietary branched-chain amino acids and the risk of cardiovascular diseases in Chinese patients with type 2 diabetes: A hospital-based case–control study

open access: yesFrontiers in Nutrition, 2022
BackgroundPrevious studies showed conflicting evidence on the association between the intake of dietary branched-chain amino acid (BCAA) and the risk of cardiovascular disease (CVD). However, this relationship has not been studied in patients with type 2
Lu Zheng   +15 more
doaj   +1 more source

Isoleucine Hydroxamate, an Isoleucine Antagonist [PDF]

open access: yesJournal of Bacteriology, 1971
Isoleucine hydroxamate (Ile·Hdx) was found to inhibit the growth of Serratia marcescens and to antagonize isoleucine. At a low concentration of Ile·Hdx, at which the growth of the wild strain was completely inhibited, the growth of an isoleucine auxotroph was not inhibited in the medium containing a limiting amount ...
M, Kisumi   +3 more
openaire   +2 more sources

Titration of dietary isoleucine and evaluation of branched-chain amino acid levels in female Cobb 500 broilers during a 22- to 42-day finisher period

open access: yesJournal of Applied Poultry Research, 2022
SUMMARY: Recent research into the branched-chain amino acids has indicated that broiler responses to dietary isoleucine may vary from classic data. Current isoleucine data has focused on male broilers leaving a gap in the literature for female data.
C.W. Maynard   +8 more
doaj   +1 more source

Determining the optimum digestible isoleucine to lysine ratio for Ross 708 x Ross YP male broilers from 0 to 18 d of age

open access: yesJournal of Applied Poultry Research, 2022
SUMMARY: Continuous genetic improvement of high yielding broiler strains necessitates reevaluation of amino acid requirements. The objective of this study was to evaluate the dIle requirement of Ross 708 x Ross YP male broilers from d 0 to 18 ...
A.T. Brown   +4 more
doaj   +1 more source

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