Results 321 to 330 of about 370,636 (381)
Some of the next articles are maybe not open access.
SAR1B senses leucine levels to regulate mTORC1 signalling
Nature, 2021Jie Chen, Peng R Chen, Ying Liu
exaly +2 more sources
Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease
Nature, 2001C Gower-rousseau +2 more
exaly +2 more sources
The leucine zipper: a hypothetical structure common to a new class of DNA binding proteins.
Science, 1988A 30-amino-acid segment of C/EBP, a newly discovered enhancer binding protein, shares notable sequence similarity with a segment of the cellular Myc transforming protein.
W. Landschulz, P. Johnson, S. McKnight
semanticscholar +1 more source
Characterization of leucine-leucine transport in leaf tissues
Journal of Experimental Botany, 1996Uptake of the dipeptide [3H]Leu-Leu into leaf discs from mature broad bean (Vicia faba L.) was characterized. Uptake was maximal at pH 6.0 and appeared to be mediated by three systems with apparent Km values of 20 µM, 350 µM and 43 mM, respectively.
Andrée Bourbouloux +4 more
openaire +3 more sources
Experientia, 1981
Trypsin-catalyzed coupling of porcine desoctapeptide-insulin with synthetic octapeptides produced the [LeuB24]- (I), [LeuB25]- (II) and [LeuB24, LeuB25]- (III)analogues of human insulin. I, II and III displayed respectively 20--30%, 1--2% and 0.5% of the receptor binding activity of the normal hormone. Biological activities of these analogues seemed to
T. Kanaya +5 more
openaire +3 more sources
Trypsin-catalyzed coupling of porcine desoctapeptide-insulin with synthetic octapeptides produced the [LeuB24]- (I), [LeuB25]- (II) and [LeuB24, LeuB25]- (III)analogues of human insulin. I, II and III displayed respectively 20--30%, 1--2% and 0.5% of the receptor binding activity of the normal hormone. Biological activities of these analogues seemed to
T. Kanaya +5 more
openaire +3 more sources
Leucine kinetics at graded leucine intakes in young men
The American Journal of Clinical Nutrition, 1986A study was carried out with 12 young men to examine the relationships between the intake of leucine and indices of leucine kinetics, using L-[1-13C]leucine as a tracer. Six subjects received L-amino acid diets during 7-day periods supplying leucine in the range of 79 to 20 mg.kg-1.day-1 (Group I) and another six subjects (Group II) received leucine ...
Vernon R. Young +5 more
openaire +3 more sources
Addition of leucine precursors to the diet of leucine-starved mice
The American Journal of Clinical Nutrition, 1975Leucine-starved mice placed on a diet supplemented with the immediate precursor of leucine, alpha-ketoisocaproic acid, regain lost weight. This weight gain is similar to that observed when the leucine-starved mice are provided with leucine in their diet.
Michael E. Trigg +4 more
openaire +3 more sources
Metabolism of leucine in fibroblasts with defects in the leucine catabolic pathway
International Journal of Biochemistry, 19871. The activity of the leucine catabolic pathway was measured by quantitation of the radiolabeled glutamic acid produced by intact cultured fibroblasts incubated with radiolabeled leucine. 2. Five normal cell lines produced an average of 179 +/- 47 pmol glutamic acid/mg cell protein/hr. 3.
William L. Nyhan, Theodore Page
openaire +3 more sources
New England Journal of Medicine, 1962
SPONTANEOUS hypoglycemia in infancy may, on rare occasions, be precipitated by the ingestion of casein, L-leucine or isovaleric acid, an intermediary metabolite of leucine.1 2 3 4 Recently, this phenomenon of "leucine-induced hypoglycemia" was observed to be associated with a rise in plasma insulin level.5 , 6 A case of leucine-induced hypoglycemia in ...
Heskel M. Haddad +3 more
openaire +3 more sources
SPONTANEOUS hypoglycemia in infancy may, on rare occasions, be precipitated by the ingestion of casein, L-leucine or isovaleric acid, an intermediary metabolite of leucine.1 2 3 4 Recently, this phenomenon of "leucine-induced hypoglycemia" was observed to be associated with a rise in plasma insulin level.5 , 6 A case of leucine-induced hypoglycemia in ...
Heskel M. Haddad +3 more
openaire +3 more sources
Leucine aminopeptase in the spleen
Experientia, 1962Leucinaminopeptidase wird histochemisch in der Milz von Mausen und Ratten untersucht. Eine besonders ausgepragte Reaktion zeigte sich in der Zentralarterienwandung und in den umgebenden Reticulumzellen der weissen Pulpa. Im Bereich der roten Pulpa verhalten sich nur die Inseln positiv, wahrend eine extramedullare Hamatopoese vorkommt.
S. Ruponen, L. K. Korhonen
openaire +3 more sources