Phosphonic Acid Analogues of Phenylglycine as Inhibitors of Aminopeptidases: Comparison of Porcine Aminopeptidase N, Bovine Leucine Aminopeptidase, Tomato Acidic Leucine Aminopeptidase and Aminopeptidase from Barley Seeds [PDF]
Pharmaceuticals, 2019 The inhibitory activity of 14 racemic phosphonic acid analogs of phenylglycine, substituted in aromatic rings, towards porcine aminopeptidase N (pAPN) and barley seed aminopeptidase was determined experimentally.
Weronika Wanat +3 more
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Essential Role for an M17 Leucine Aminopeptidase in Encystation of Acanthamoeba castellanii. [PDF]
PLoS ONE, 2015 Encystation of Acanthamoeba leads to the formation of resilient cysts from vegetative trophozoites. This process is essential for parasite survival under unfavorable conditions such as starvation, low temperatures, and exposure to biocides.
Yu-Ran Lee +8 more
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Leucine Aminopeptidase to Spleen Length Ratio: A Novel Noninvasive Model for Predicting Esophageal Gastric Variceal Bleeding in Patients With Liver Cirrhosis [PDF]
Gastroenterology Research and Practice, Volume 2026, Issue 1, 2026.Background Esophageal gastric variceal bleeding (EGVB) is a common complication of liver cirrhosis. However, esophagogastroduodenoscopy (EGD) for detecting venous pressure is invasive, limiting its clinical application. To reduce unnecessary EGD screening, here we screened multiple commonly used noninvasive examination indicators and evaluated their ...
Chen Zhu +5 more
wiley +2 more sources
Characterization and structural analysis of a leucine aminopeptidase using site-directed mutagenesis [PDF]
AMB ExpressAmp0279 (EC 3.4.11.24, GenBank: CP000817.1) is a Co2+-dependent leucine aminopeptidase from the Lysinibacillus sphaericus C3-41 genome. After analyses using molecular docking and spatial structure analysis, site-directed mutagenesis mutants were ...
Yuqi Men +6 more
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A leucine aminopeptidase is involved in kinetoplast DNA segregation in Trypanosoma brucei. [PDF]
PLoS Pathogens, 2017 The kinetoplast (k), the uniquely packaged mitochondrial DNA of trypanosomatid protists is formed by a catenated network of minicircles and maxicircles that divide and segregate once each cell cycle.
Priscila Peña-Diaz +4 more
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Safety evaluation of the food enzyme leucyl aminopeptidase from the non‐genetically modified Lichtheimia ramosa strain AE‐PER [PDF]
EFSA JournalThe food enzyme leucyl aminopeptidase (EC 3.4.11.1) is produced with the non‐genetically modified Lichtheimia ramosa strain AE‐PER by Amano Enzyme Inc. The food enzyme was considered free from viable cells of the production organism.
EFSA Panel on Food Enzymes (FEZ) +17 more
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Structural and Functional Basis of Potent Inhibition of Leishmanial Leucine Aminopeptidase by Peptidomimetics [PDF]
ACS Omega, 2021 Saleem Yousuf Bhat, Insaf Ahmed Qureshi
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Extracellular Proteome Analysis and Flavor Formation During Soy Sauce Fermentation
Frontiers in Microbiology, 2018 Aspergillus oryzae is an excellent strain for soy sauce fermentation because of its complicated enzyme system, especially protease. The aim of this study was to investigate the key enzymes and flavors during soy sauce fermentation, and a comparative ...
Guozhong Zhao +5 more
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Effects of biochar application on soil enzyme activities in Eucalyptus plantations in North Guangxi
Guangxi Zhiwu, 2023 To investigate the effects of different biochar applications on soil enzyme activities in Eucalyptus plantations in North Guangxi, and provide theoretical references for the rational application of biochar to Eucalyptus plantations.
Zhiyi MOU +9 more
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Localization of leucine aminopeptidase isoenzymes [PDF]
Journal of Clinical Pathology, 1964 A simple, sensitive staining procedure for the localization of leucine aminopeptidase isoenzymes after electrophoretic separation on cellulose acetate membranes is described. Separation of leucine aminopeptidase isoenzymes, using cellulose acetate membranes, does not appear to be a rewarding diagnostic procedure in the investigation of hepatobiliary or
B W, MEADE, S B, ROSALKI
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