Results 91 to 100 of about 3,849 (186)

Stronger inflammatory/cytotoxic T cell response in women identified by microarray analysis [PDF]

, 2008
Women develop chronic inflammatory autoimmune diseases like lupus more often than men. The mechanisms causing the increased susceptibility are incompletely understood, although estrogen is believed to contribute.
Anura Hewagama, Bruce C. Richardson, Dipak Patel, Faith M. Strickland, Sushma Yarlagadda   +4 more
core   +1 more source

Antibiotics Increase Gut Metabolism and Antioxidant Proteins and Decrease Acute Phase Response and Necrotizing Enterocolitis in Preterm Neonates [PDF]

, 2012
Background: The appropriate use of antibiotics for preterm infants, which are highly susceptible to develop necrotizing enterocolitis (NEC), is not clear.
Cilieborg, MS, Jensen, ML, Jiang, P, Sangild, PT, Sit, WH, Thymann, T, Tipoe, GL, Wan, JMF   +7 more
core   +1 more source

Role of β-glucans in reducing oxidative stress and improving muscle tissue health in European whitefish (Coregonus lavaretus L.)

Fisheries & Aquatic Life
β-glucans are currently a notable topic in research on enhancing immunity in fishes and their significant role in improving fish health and productivity in aquaculture.
Tkaczenko Halina, Grudniewska Joanna, Kurhaluk Natalia   +2 more
doaj   +1 more source

Alternative Antigen Processing for MHC Class I: Multiple Roads Lead to Rome [PDF]

, 2015
The well described conventional antigen processing pathway is accountable for most peptides that end up in MHC class I molecules at the cell surface. These peptides experienced liberation by the proteasome and transport by the peptide transporter TAP ...
Aldrich, Aldrich, Bartoszewski, Bland, Braud, Cascio, Cerundolo, Chapman, Chemali, Chen, Christianson, Cresswell, Crotzer, Dalbey, de Almeida, de la Salle, Del Val, Durgeau, El Hage, English, Fluhrer, Friedmann, Garstka, Geier, Gil-Torregrosa, Glas, Henderson, Hermann, Hu, Hughes, Jahreiss, Jensen, Jeon, Johnson, Kessler, Kim, Kisselev, Klein, Kloetzel, Koble, Lampen, Lampen, Lampen, Lautscham, Lee, Lemberg, Lemberg, Leonhardt, Levine, Levy, Li, Lilley, Lorente, Lorente, Loureiro, Lu, Lyko, Martoglio, Medina, Mijaljica, Momburg, Munz, Nagarajan, Nam, Nam, Neefjes, Oehler, Oliveira, Oliveira, Oliveira, Oliveira, Parmentier, Rapoport, Reits, Reits, Riebeling, Rock, Rodgers, Sandberg, Saric, Saric, Schrul, Sebzda, Seidah, Seidah, Seidel, Seifert, Serwold, Snyder, Snyder, Snyder, Song, Spee, Susan-Resiga, Targett-Adams, Targett-Adams, Tey, Thomas, Tiwari, Urban, van de Weijer, van der Wal, van Hall, van Hall, Van Hall, Van Kaer, Voss, Vyas, Wang, Wearsch, Wei, Weihofen, Weihofen, Weinzierl, Wiertz, Wolpert, Yamada, Yewdell, Yorimitsu, York, York, Zimmer   +121 more
core   +2 more sources

Aminopeptidases in Mycelium and Growth Medium of Streptomyces rimosus Strains

Food Technology and Biotechnology, 2009
Aminopeptidases (APs) of the same substrate specificities have been detected in the mycelia and culture filtrate of Streptomyces rimosus. To compare extracellular and intracellular prolyl, leucyl and arginyl AP, dynamics of their biosynthesis, excretion ...
Jasminka Špoljarić, Bojana Vukelić, Ljubinka Vitale   +2 more
doaj  

Post-translational processing targets functionally diverse proteins in Mycoplasma hyopneumoniae [PDF]

, 2016
© 2016 The Authors. Mycoplasma hyopneumoniae is a genome-reduced, cell wall-less, bacterial pathogen with a predicted coding capacity of less than 700 proteins and is one of the smallest self-replicating pathogens. The cell surface of M. hyopneumoniae is
Berry, IJ, Bogema, DR, Djordjevic, SP, Haynes, PA, Jenkins, C, Minion, FC, Padula, MP, Raymond, BBA, Tacchi, JL, Widjaja, M, Woolley, LK   +10 more
core   +2 more sources

Expression, Characterisation, Homology Modelling and Molecular Docking of a Novel M17 Family Leucyl-Aminopeptidase from Bacillus cereus CZ. [PDF]

Int J Mol Sci, 2023
Liu J, Cui T.
europepmc   +1 more source

Identification of a potent and selective LAPTc inhibitor by RapidFire-Mass Spectrometry, with antichagasic activity.

PLoS Neglected Tropical Diseases
BackgroundChagas disease is caused by the protozoan parasite Trypanosoma cruzi and leads to ~10,000 deaths each year. Nifurtimox and benznidazole are the only two drugs available but have significant adverse effects and limited efficacy.
Maikel Izquierdo, De Lin, Sandra O'Neill, Lauren A Webster, Christy Paterson, John Thomas, Mirtha Elisa Aguado, Enrique Colina Araújo, Daniel Alpízar-Pedraza, Halimatu Joji, Lorna MacLean, Anthony Hope, David W Gray, Martin Zoltner, Mark C Field, Jorge González-Bacerio, Manu De Rycker   +16 more
doaj   +1 more source

Ubenimex synergizes with the PD-L1 blockade in gastric cancer by competitively binding LAP3 with UBE3A

Cell Death and Disease
Immune checkpoint inhibitors (ICIs), particularly PD-1/PD-L1 blockade, represent a cornerstone of treatment for advanced gastric cancer (GC). However, their clinical efficacy is hampered by low response rates and the development of both primary and ...
Caixia Zhao, Jiaxin Li, Jinxiu Zheng, Ming Chi, Ying Shao, Yuxin Che, Wenjing Chen, Jie Dai, Chunxia Chen, Xiaoning Li, Likun Zan, Yu Shi, Yujing Duan, Lijun Yang, Tao Yang   +14 more
doaj   +1 more source

Influence of age of aggregates and prokaryotic abundance on glucose and leucine uptake by heterotrophic marine prokaryotes [PDF]

, 2008
The kinetics of glucose and leucine uptake in attached and free-living prokaryotes in two types of microcosms with different nutrient qualities were compared.
Begoña Ayo, Itxaso Artolozaga, Iñigo Azúa, Juan Iriberri, Marian Unanue   +4 more
core   +1 more source