Results 71 to 80 of about 16,120 (166)

A Modular and Customizable CRISPR/Cas Toolkit for Epigenome Editing of Cis‐regulatory Modules

Advanced Science, Volume 12, Issue 47, December 18, 2025.
Epigenome editing surpasses genome editing in gene regulation. Modular epigenome editing frameworks are developed to interrogate cis‐regulome, enabling tunable reprogramming of cis‐elements, uncovering their epigenetic responsiveness and cross‐species portability.
Lingrui Zhang, Jianxin Fu, Tiandan Long, Chao Zhang, Fuhua Fan, Zhaobo Lang, Jian‐Kang Zhu   +6 more
wiley   +1 more source

COMPARISON OF FIXATIVES AND SUBSTRATES FOR AMINOPEPTIDASE

, 1965
Although aminopeptidase activity is extensively inhibited by glutaraldehyde, it is sufficiently well preserved after brief glutaraldehyde fixation for histochemical use in active tissues in contrast to the too great losses with comparable formaldehyde ...
HANNAH WASSERKRUG, BENITO MONIS, ARNOLD M. SELIGMAN   +2 more
core   +1 more source

The Concise Guide to PHARMACOLOGY 2025/26: Enzymes

British Journal of Pharmacology, Volume 182, Issue S1, Page S307-S403, December 2025.
The Concise Guide to Pharmacology 2025/26 marks the seventh edition in this series of biennial publications in the British Journal of Pharmacology. Presented in landscape format, the guide provides a comparative overview of the pharmacology of drug target families. The concise nature of the Concise Guide refers to the style of presentation, being clear,
Stephen P. H. Alexander, Doriano Fabbro, Alasdair J. Gibb, Eamonn Kelly, Alistair A. Mathie, Chloe J. Peach, Emma L. Veale, Jane F. Armstrong, Elena Faccenda, Simon D. Harding, Christopher Southan, Jamie A. Davies, Stephanie Annett, Detlev Boison, Kathryn Elisa Burns, Carmen Dessauer, Jürg Gertsch, Nuala Ann Helsby, Angelo A. Izzo, Rennolds Ostrom, Ester Pagano, Andreas Papapetropoulos, Nigel J. Pyne, Susan Pyne, Tracy Robson, Roland Seifert, Johannes‐Peter Stasch, Csaba Szabo, Mario van der Stelt, Albert van der Vliet, Val Watts, Szu Shen Wong   +31 more
wiley   +1 more source

Modulation of oxidative stress biomarkers and lysosomal functioning in gills and liver of rainbow trout (Oncorhynchus mykiss Walbaum) fed a diet supplemented with yeast β-glucans

Fisheries & Aquatic Life
The present study was performed to investigate the effects of dietary yeast β-1,3/1,6-D-glucans after 15-, 30-, and 45-day feeding periods on the development of oxidative stress, antioxidant defenses, and lysosomal functioning in gills and hepatic tissue
Kurhaluk Natalia, Grudniewska Joanna, Tkaczenko Halina   +2 more
doaj   +1 more source

A Liposome-Forming Caged Compound:  Synthesis and Photochemical Properties of a Caged l-Leucyl-l-leucine Methyl Ester with a Steroid Skeleton

, 2016
A Liposome-Forming Caged Compound:  Synthesis and Photochemical Properties of a Caged l-Leucyl-l-leucine Methyl Ester with a Steroid ...
Soichiro Watanabe (634249), Michiko Iwamura (2692975)   +1 more
core   +1 more source

LINF_230017800

Cytosolic leucyl aminopeptidase | LAP1; Leishmania infantum (strain ...
Requena, Jose M.
core   +1 more source

Transpeptidase Activity of E. Coli Aminopeptidase I

, 1980
The transpeptidase activity of the proteolytic enzyme aminopeptidase' I from Escherichia coli, K-12 has been investigated. The enzyme was found capable of catalyzing peptidyl transfer with the substrates L-leucyl-L-leucine, L-leueylglycine, and L ...
Bottcher, Judith
core  

In vivo Effects of Lambda-cyhalothrin on Proteases of Various Body Compartments of Periplaneta americana Adults

The overall activity and body comportment distribution of a wide range of cytoplasmic and lysosomal proteolytic enzymes was determined in the adults of American cockroach, Periplaneta americana. Individual proteolytic enzymes showed different overall and
Shakoori AR, Saleem MA, Wilkins RM
core   +5 more sources

Brugia malayi excreted/secreted proteins at the host/parasite interface: stage- and gender-specific proteomic profiling.

PLoS Neglected Tropical Diseases, 2009
Relatively little is known about the filarial proteins that interact with the human host. Although the filarial genome has recently been completed, protein profiles have been limited to only a few recombinants or purified proteins of interest.
Sasisekhar Bennuru, Roshanak Semnani, Zhaojing Meng, Jose M C Ribeiro, Timothy D Veenstra, Thomas B Nutman   +5 more
doaj   +1 more source

Inhibition of Aminopeptidase I

, 1978
The inhibition of aminopeptidase I from Eschericia coli K12 by several dipeptides, which are not hydrolyzed by the enzyme, has been examined quantitatively. The dissociation constants (K,) of three of these inhibitors with the enzyme have been determined.
Cabilio, Juta
core