Results 51 to 60 of about 1,785 (131)

Aminopeptidases in Mycelium and Growth Medium of Streptomyces rimosus Strains

Food Technology and Biotechnology, 2009
Aminopeptidases (APs) of the same substrate specificities have been detected in the mycelia and culture filtrate of Streptomyces rimosus. To compare extracellular and intracellular prolyl, leucyl and arginyl AP, dynamics of their biosynthesis, excretion ...
Jasminka Špoljarić, Bojana Vukelić, Ljubinka Vitale   +2 more
doaj  

Expression, Characterisation, Homology Modelling and Molecular Docking of a Novel M17 Family Leucyl-Aminopeptidase from Bacillus cereus CZ. [PDF]

Int J Mol Sci, 2023
Liu J, Cui T.
europepmc   +1 more source

Identification of a potent and selective LAPTc inhibitor by RapidFire-Mass Spectrometry, with antichagasic activity.

PLoS Neglected Tropical Diseases
BackgroundChagas disease is caused by the protozoan parasite Trypanosoma cruzi and leads to ~10,000 deaths each year. Nifurtimox and benznidazole are the only two drugs available but have significant adverse effects and limited efficacy.
Maikel Izquierdo, De Lin, Sandra O'Neill, Lauren A Webster, Christy Paterson, John Thomas, Mirtha Elisa Aguado, Enrique Colina Araújo, Daniel Alpízar-Pedraza, Halimatu Joji, Lorna MacLean, Anthony Hope, David W Gray, Martin Zoltner, Mark C Field, Jorge González-Bacerio, Manu De Rycker   +16 more
doaj   +1 more source

Ubenimex synergizes with the PD-L1 blockade in gastric cancer by competitively binding LAP3 with UBE3A

Cell Death and Disease
Immune checkpoint inhibitors (ICIs), particularly PD-1/PD-L1 blockade, represent a cornerstone of treatment for advanced gastric cancer (GC). However, their clinical efficacy is hampered by low response rates and the development of both primary and ...
Caixia Zhao, Jiaxin Li, Jinxiu Zheng, Ming Chi, Ying Shao, Yuxin Che, Wenjing Chen, Jie Dai, Chunxia Chen, Xiaoning Li, Likun Zan, Yu Shi, Yujing Duan, Lijun Yang, Tao Yang   +14 more
doaj   +1 more source

Overexpression of Leucyl Aminopeptidase in Plasmodium falciparum Parasites [PDF]

Journal of Biological Chemistry, 2006
Donald L. Gardiner, Katharine R. Trenholme, Tina S. Skinner-Adams, Colin M. Stack, John P. Dalton   +4 more
openaire   +1 more source

Genome-wide mapping of the binding sites of myocyte enhancer factor 2A in chicken primary myoblasts

Poultry Science
: Myocyte enhancer factor 2A (MEF2A) is a transcription factor that plays a critical role in cell proliferation, differentiation and apoptosis. In contrast to the wide characterization of its regulation mechanism in mammalian skeletal muscle, its role in
Xinglong Wang, Jiannan Zhang, Jiancheng Su, Tianjiao Huang, Ling Lian, Qinghua Nie, Xin Zhang, Juan Li, Yajun Wang   +8 more
doaj   +1 more source

Characterization of the Plasmodium falciparum M17 Leucyl Aminopeptidase [PDF]

Journal of Biological Chemistry, 2007
Colin M. Stack, Jonathan Lowther, Eithne Cunningham, Sheila Donnelly, Donald L. Gardiner, Katharine R. Trenholme, Tina S. Skinner-Adams, Franka Teuscher, Jolanta Grembecka, Artur Mucha, Pawel Kafarski, Linda Lua, Angus Bell, John P. Dalton   +13 more
openaire   +1 more source

Plasmodium falciparum M17 leucyl aminopeptidase (M17) [PDF]

Science-Business eXchange, 2010
openaire   +1 more source

The major leucyl aminopeptidase of Trypanosoma cruzi (LAPTc) assembles into a homohexamer and belongs to the M17 family of metallopeptidases. [PDF]

BMC Biochem, 2011
Cadavid-Restrepo G, Gastardelo TS, Faudry E, de Almeida H, Bastos IM, Negreiros RS, Lima MM, Assumpção TC, Almeida KC, Ragno M, Ebel C, Ribeiro BM, Felix CR, Santana JM.   +13 more
europepmc   +1 more source

Role of insulin-regulated aminopeptidase as potential biomarker in insulin resistant polycystic ovary syndrome patients. [PDF]

Arch Endocrinol Metab
Köse O, Gök K, Köse E, Gözükara SI, Tüten A, Bostancı MS.   +5 more
europepmc   +1 more source