Results 51 to 60 of about 3,849 (186)

The Aminopeptidase CD13 Induces Homotypic Aggregation in Neutrophils and Impairs Collagen Invasion. [PDF]

, 2016
Aminopeptidase N (CD13) is a widely expressed cell surface metallopeptidase involved in the migration of cancer and endothelial cells. Apart from our demonstration that CD13 modulates the efficacy of tumor necrosis factor-α-induced apoptosis in ...
A Kehlen, AE Bryant, Amit Gaggar, AN Santos, Andrew S. Cowburn, AS Cowburn, B Malleret, B Winnicka, C Capodici, C Haslett, Christine A. Fiddler, D Luo, DA Mackenzie, DE Hammerschmidt, Ding Luo, Edwin R. Chilvers, G Liu, Gerard B. Nash, Gillian Murphy, H Fujii, H Fujii, Helen Parfrey, J Subramani, JK Juss, JM Hallenbeck, K Fukasawa, K Jewell, K Makni-Maalej, KA Brown, L Guzman-Rojas, L József, M Faurschou, M Hegen, M Terauchi, N Petrovic, NN McGovern, P Friedl, P Mina-Osorio, P Mina-Osorio, P Mina-Osorio, PC Wilkinson, RA Ashmun, RA Ashmun, S Roth, SI Simon, T Schmidt, T Werfel, T Yoshikawa, VJ Burton, YP Rochon   +49 more
core   +11 more sources

TrpM, a Small Protein Modulating Tryptophan Biosynthesis and Morpho-Physiological Differentiation in Streptomyces coelicolor A3(2). [PDF]

PLoS ONE, 2016
In the model actinomycete Streptomyces coelicolor A3(2), small open reading frames encoding proteins with unknown functions were identified in several amino acid biosynthetic gene operons, such as SCO2038 (trpX) in the tryptophan trpCXBA locus.
Emilia Palazzotto, Giuseppe Gallo, Giovanni Renzone, Anna Giardina, Alberto Sutera, Joohee Silva, Celinè Vocat, Luigi Botta, Andrea Scaloni, Anna Maria Puglia   +9 more
doaj   +1 more source

Experimental Evidence for a Metallohydrolase Mechanism in Which the Nucleophile Is Not Delivered by a Metal Ion: EPR Spectrokinetic and Structural Studies of Aminopeptidase from \u3cem\u3eVibrio proteolyticus\u3c/em\u3e [PDF]

, 2007
Metallohydrolases catalyse some of the most important reactions in biology and are targets for numerous chemotherapeutic agents designed to combat bacterial infectivity, antibiotic resistance, HIV infectivity, tumour growth, angiogenesis and immune ...
Bennett, Brian, Kim, Jung Ja, Kittell, Aaron W., Kumar, Amit, Periyannan, Gopal R.   +4 more
core   +1 more source

Influence of nutrient substrates on the expression of cellulases in Cerambyx cerdo L. (Coleoptera: Cerambycidae) larvae [PDF]

, 2012
The expression and distribution of digestive cellulases along the midgut of Cerambyx cerdo larvae were analyzed for the first time and are presented in this article.
Dojnov Biljana, Grujić Marica, Ivanović Jelisaveta, Nenadović Vera, Pavlović R., Vujčić Miroslava, Vujčić Z.   +6 more
core   +5 more sources

Mechanisms of Aristolochic Acid Resistance in Specialist Butterflies and Evolutionary Insights for Potential Protective Pathways

Advanced Science, Volume 13, Issue 19, 2 April 2026.
The study provides an extreme example of insect adaptation to highly toxic defenses of host plants, and investigates the complex strategies to resist carcinogenic aristolochic acids, including physical isolation, metabolic detoxification, and DNA repair.
Yang Luan, Yubo Zhang, Jingjing Li, Jianqing Zhu, Yuyang Lei, Yushi Hu, Zhenqiang Xin, Tianpei Xie, Jiang Zheng, Yuanyuan Lin, Jingjing Shen, Yiyi Cao, Xinyue You, Jing Xi, Jiaying Wu, Weiying Liu, Xinyu Zhang, Yuanting Zheng, David J. Lohman, Leming Shi, Wei Zhang   +20 more
wiley   +1 more source

Differences in virus receptor for type I and type II feline infectious peritonitis virus. [PDF]

, 1998
Feline infectious peritonitis viruses (FIPVs) are classified into type I and type II serogroups. Here, we report that feline aminopeptidase N (APN), a cell-surface metalloprotease on the intestinal, lung and kidney epithelial cells, is a receptor for ...
Hohdatsu, T, Izumiya, Y, Kida, K, Koyama, H, Yokoyama, Y   +4 more
core  

Identifcation of small molecule enzyme inhibitors as broad-spectrum anthelmintics [PDF]

, 2019
Targeting chokepoint enzymes in metabolic pathways has led to new drugs for cancers, autoimmune disorders and infectious diseases. This is also a cornerstone approach for discovery and development of anthelmintics against nematode and flatworm parasites.
Aroian, Raffi V., Brindley, Paul J., Bulman, Christina A., Elfawal, Mostafa A., Helander, Jon, Janetka, James W., Mitreva, Makedonka, Rosa, Bruce A., Sakanari, Judy, Tyagi, Rahul, Wildman, Scott A.   +10 more
core   +3 more sources

Microbial Resistance and Resilience to Short‐Term Drought Varies Among Grasslands Spanning a Broad Precipitation Gradient

Grass and Forage Science, Volume 81, Issue 2, April-June 2026.
ABSTRACT Drought is increasing in severity and duration across the United States, particularly in arid and semi‐arid regions. Previous research has shown that drought has strong impacts in drier versus more mesic regions for aboveground productivity.
Leena L. Vilonen, Melinda D. Smith, Jing Yuan, Pankaj Trivedi   +3 more
wiley   +1 more source

A comparative study of an aminopeptidase from lactic acid bacteria: a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Biochemistry at Massey University [PDF]

, 1992
Aminopeptidase enzymes from the proteolytic systems of S.salivarius subsp.thermophilus Lactococcus lactis subsp.cremoris and Lactococcus lactis subsp.lactis have been investigated.
Midwinter, Robyn Gillian
core  

Ankylosing Spondylitis: a trade Off of HLA-B27, ERAP, and pathogen interconnections? Focus on Sardinia [PDF]

, 2019
The frequency of HLA-B27 in patients with Ankylosing Spondylitis (AS) is over 85%. There are more than 170 recognized HLA-B27 alleles but the majority of them is not sufficiently represented for genetic association studies.
Cauli, A, Fiorillo, Mt, Mathieu, A, Paladini, F, Sorrentino, R., Tedeschi, V   +5 more
core   +2 more sources