Results 51 to 60 of about 1,860 (145)

Unravelling potential virulence factor candidates in Xanthomonas citri. subsp. citri by secretome analysis [PDF]

PeerJ, 2016
Citrus canker is a major disease affecting citrus production in Brazil. It’s mainly caused by Xanthomonas citri subsp. citri strain 306 pathotype A (Xac).
Rafael M. Ferreira, Leandro M. Moreira, Jesus A. Ferro, Marcia R.R. Soares, Marcelo L. Laia, Alessandro M. Varani, Julio C.F. de Oliveira, Maria Ines T. Ferro   +7 more
doaj   +2 more sources

Diverse Biological Functions and Domain‐Specific Interactions of the Diguanylate Cyclase PA2072 in Pseudomonas aeruginosa PAO1

International Journal of Microbiology, Volume 2026, Issue 1, 2026.
Nucleotide bis‐(3,5)‐cyclic di‐guanosine monophosphate (c‐di‐GMP) is a universal and versatile secondary messenger. It is involved in the regulation of significant functions such as motility, biofilm formation, virulence, drug resistance, cell cycle, differentiation, and many other physiological processes in bacteria.
Xiaojing Gao, Yan Zhang, Lingna Guo, Huimin Zhang, Jianwen Sun, Jianfang Sun, Weidong Huang, Abdelwahab Omri   +7 more
wiley   +1 more source

A Modular and Customizable CRISPR/Cas Toolkit for Epigenome Editing of Cis‐regulatory Modules

Advanced Science, Volume 12, Issue 47, December 18, 2025.
Epigenome editing surpasses genome editing in gene regulation. Modular epigenome editing frameworks are developed to interrogate cis‐regulome, enabling tunable reprogramming of cis‐elements, uncovering their epigenetic responsiveness and cross‐species portability.
Lingrui Zhang, Jianxin Fu, Tiandan Long, Chao Zhang, Fuhua Fan, Zhaobo Lang, Jian‐Kang Zhu   +6 more
wiley   +1 more source

The Role of Aminopeptidase ERAP1 in Human Pathology—A Review

Current Issues in Molecular Biology
Aminopeptidases are a group of enzymatic proteins crucial for protein digestion, catalyzing the cleavage of amino acids at the N-terminus of peptides. Among them are ERAP1 (coding for endoplasmic reticulum aminopeptidase 1), ERAP2 (coding for endoplasmic
Laura Țiburcă, Dana Carmen Zaha, Maria Claudia Jurca, Emilia Severin, Aurora Jurca, Alexandru Daniel Jurca   +5 more
doaj   +1 more source

The Concise Guide to PHARMACOLOGY 2025/26: Enzymes

British Journal of Pharmacology, Volume 182, Issue S1, Page S307-S403, December 2025.
The Concise Guide to Pharmacology 2025/26 marks the seventh edition in this series of biennial publications in the British Journal of Pharmacology. Presented in landscape format, the guide provides a comparative overview of the pharmacology of drug target families. The concise nature of the Concise Guide refers to the style of presentation, being clear,
Stephen P. H. Alexander, Doriano Fabbro, Alasdair J. Gibb, Eamonn Kelly, Alistair A. Mathie, Chloe J. Peach, Emma L. Veale, Jane F. Armstrong, Elena Faccenda, Simon D. Harding, Christopher Southan, Jamie A. Davies, Stephanie Annett, Detlev Boison, Kathryn Elisa Burns, Carmen Dessauer, Jürg Gertsch, Nuala Ann Helsby, Angelo A. Izzo, Rennolds Ostrom, Ester Pagano, Andreas Papapetropoulos, Nigel J. Pyne, Susan Pyne, Tracy Robson, Roland Seifert, Johannes‐Peter Stasch, Csaba Szabo, Mario van der Stelt, Albert van der Vliet, Val Watts, Szu Shen Wong   +31 more
wiley   +1 more source

A Viral RNA Silencing Suppressor Modulates Reactive Oxygen Species Levels to Induce the Autophagic Degradation of Dicer‐Like and Argonaute‐Like Proteins

Advanced Science, Volume 12, Issue 44, November 27, 2025.
Understanding the virus‐host arms race has been a fascinating topic in virology; contributing significantly to the development of treatments and control strategies for viral diseases. CHV1 employs a sophisticated counter‐defense mechanism in its fungal host by utilizing a viral silencing suppressor to inhibit fungal FMN reductase; thereby modulating ...
Shiyu Zhai, Tianxing Pang, Shiyu Peng, Shenshen Zou, Zhiping Deng, Nobuhiro Suzuki, Zhensheng Kang, Ida Bagus Andika, Liying Sun   +8 more
wiley   +1 more source

Fish By‐Products Utilization in Food and Health: Extraction Technologies, Bioactive, and Sustainability Challenges

Food Science &Nutrition, Volume 13, Issue 11, November 2025.
Fish by‐products, often discarded, are rich sources of bioactive peptides, collagen, and omega‐3s with antioxidant, antihypertensive, and antimicrobial properties. Advanced, sustainable extraction technologies can valorize this waste into functional food, nutraceutical, and biomedical ingredients.
Muhammad Waqar, Nimra Sajjad, Qudrat Ullah, S. S. Vasanthkumar, Faiyaz Ahmed, Worawan Panpipat, Rotimi E. Aluko, Lovedeep Kaur, Manat Chaijan, Temesgen Anjulo Ageru   +9 more
wiley   +1 more source

Peeling Skin, Leukonychia, Acral Punctate Keratoses, Cheilitis and Knuckle Pads (PLACK) Syndrome: An Updated Review of Cases and Identification of a Recurrent CAST Variant in Two Patients

Pediatric Dermatology, Volume 42, Issue 6, Page 1239-1247, November/December 2025.
ABSTRACT Peeling skin, leukonychia, acral punctate keratoses, cheilitis, and knuckle pads (PLACK) syndrome (OMIM616295) is an exceptionally rare autosomal recessive genodermatosis caused by loss‐of‐function pathogenic variants in the CAST gene, encoding calpastatin.
Fiona Haxho, Richard M. Haber, Janan Mohamad, Ofer Sarig, Eli Sprecher, Renée Perrier, Dana Boctor, Michele Ramien   +7 more
wiley   +1 more source

Modulation of oxidative stress biomarkers and lysosomal functioning in gills and liver of rainbow trout (Oncorhynchus mykiss Walbaum) fed a diet supplemented with yeast β-glucans

Fisheries & Aquatic Life
The present study was performed to investigate the effects of dietary yeast β-1,3/1,6-D-glucans after 15-, 30-, and 45-day feeding periods on the development of oxidative stress, antioxidant defenses, and lysosomal functioning in gills and hepatic tissue
Kurhaluk Natalia, Grudniewska Joanna, Tkaczenko Halina   +2 more
doaj   +1 more source

A Common Genetic Background for Psoriasis and Cardiovascular Diseases: A Narrative Review

Health Science Reports, Volume 8, Issue 8, August 2025.
ABSTRACT Background and Aims Psoriasis is an immune‐mediated disease affecting primarily the skin and joints, but which also has systemic implications. There are assumptions about a common genetic background between psoriasis and cardiovascular diseases.
Andrada‐Luciana Lazar, Cleopatra Romana Vulturar, Adela‐Viviana Sitar‐Tăut, Ramona Suharoschi, Olga Hilda Orășan, Adina Ancuța Chiș, Adriana Fodor, Brîndușa Tiperciuc, Cezar Login, Angela Cozma   +9 more
wiley   +1 more source