Results 31 to 40 of about 16,120 (166)

Identification and Validation of Compounds Targeting <i>Leishmania major</i> Leucyl-Aminopeptidase M17. [PDF]

ACS Infect Dis
داء الليشمانيات هو مرض استوائي مهمل ؛ لا يوجد حاليًا لقاح ويعتمد العلاج على حفنة من الأدوية التي تعاني من مشاكل متعددة بما في ذلك السمية والمقاومة. هناك حاجة ماسة لتطوير علاجات جديدة مناسبة للغرض، مع تقليل السمية واستهداف آليات جديدة للتغلب على المقاومة.
Aguado ME, Carvalho S, Valdés-Tresanco ME, Lin, Padilla-Mejia N, Corpas-Lopez V, Tesařová M, Lukeš J, Gray D, González-Bacerio J, Wyllie S, Field MC.   +11 more
europepmc   +5 more sources

Salt Priming as a Smart Approach to Mitigate Salt Stress in Faba Bean (Vicia faba L.)

Plants, 2022
The present investigation aims to highlight the role of salt priming in mitigating salt stress on faba bean. In the absence of priming, the results reflected an increase in H2O2 generation and lipid peroxidation in plants subjected to 200 mM salt shock ...
Amira K. Nasrallah, Mohamed A. M. Atia, Reem M. Abd El-Maksoud, Maimona A. Kord, Ahmed S. Fouad   +4 more
doaj   +1 more source

Urinary aminopeptidase activities as early and predictive biomarkers of renal dysfunction in cisplatin-treated rats. [PDF]

PLoS ONE, 2012
This study analyzes the fluorimetric determination of alanyl- (Ala), glutamyl- (Glu), leucyl-cystinyl- (Cys) and aspartyl-aminopeptidase (AspAp) urinary enzymatic activities as early and predictive biomarkers of renal dysfunction in cisplatin-treated ...
Andrés Quesada, Félix Vargas, Sebastián Montoro-Molina, Francisco O'Valle, María Dolores Rodríguez-Martínez, Antonio Osuna, Isabel Prieto, Manuel Ramírez, Rosemary Wangensteen   +8 more
doaj   +1 more source

Potential Activities and Long Lifetimes of Organic Carbon-Degrading Extracellular Enzymes in Deep Subsurface Sediments of the Baltic Sea

Frontiers in Microbiology, 2021
Heterotrophic microorganisms in marine sediments produce extracellular enzymes to hydrolyze organic macromolecules, so their products can be transported inside the cell and used for energy and growth. Therefore, extracellular enzymes may mediate the fate
Jenna M. Schmidt, Taylor M. Royalty, Karen G. Lloyd, Andrew D. Steen, Andrew D. Steen   +4 more
doaj   +1 more source

Molecular characterization of a puromycin‐insensitive leucyl‐specific aminopeptidase, PILS‐AP [PDF]

European Journal of Biochemistry, 2000
The family M1 of Zn‐dependent aminopeptidases comprises members of closely related enzymes which are known to be involved in a variety of physiologically important processes. On the basis of two highly conserved peptide motifs, we have identified a new member of this family by PCR amplification and cDNA‐library screening.
L, Schomburg, H, Kollmus, S, Friedrichsen, K, Bauer   +3 more
openaire   +4 more sources

Potential Activities of Freshwater Exo- and Endo-Acting Extracellular Peptidases in East Tennessee and the Pocono Mountains

Frontiers in Microbiology, 2018
Proteins constitute a particularly bioavailable subset of organic carbon and nitrogen in aquatic environments but must be hydrolyzed by extracellular enzymes prior to being metabolized by microorganisms.
Lauren Mullen, Malcolm X Shabazz High School Aquatic Biogeochemistry Team, Kim Boerrigter, Kim Boerrigter, Nicholas Ferriero, Jeff Rosalsky, Abigail van Buren Barrett, Patrick J. Murray, Andrew D. Steen   +8 more
doaj   +1 more source

Aminopeptidase C of Aspergillus niger is a Novel Phenylalanine Aminopeptidase [PDF]

, 2003
A novel enzyme with a specific phenylalanine aminopeptidase activity (ApsC) from Aspergillus niger (CBS 120.49) has been characterized. The derived amino acid sequence is not similar to any previously characterized aminopeptidase sequence but does share ...
Dekker, P.J.T., Basten, E.J.W., Schaap, P.J.   +2 more
core   +1 more source

Chromogenic Leucyl Substrates for Aminopeptidase and Papain

Experimental Biology and Medicine, 1955
SummaryTwo chromogenic l-leucyl aminopeptides have been prepared by a conventional method of peptide synthesis.
J E, FOLK, M S, BURSTONE
openaire   +2 more sources

Study on endogenous protease and protein degradation of dry-salted Decapterus maruadsi

CyTA - Journal of Food, 2018
Extensive proteolysis and formation of flavor substances occur during the processing of dry-salted fish due to the action of endogenous proteases. This study analyzed the evolution of the endogenous proteases and the relationship between endogenous ...
YanYan Wu, Song Min Cao
doaj   +1 more source

Expression of Oxytocin/Neurophysin I and Oxytocinase in the Equine Conceptus from Day 8 to Day 21 Post-Ovulation

Animals, 2022
Leucyl and cystinyl aminopeptidase (LNPEP/oxytocinase) is an enzyme that metabolizes oxytocin in serum and tissues. The presence of oxytocin/neurophysin I (OXT), oxytocin and LNPEP and their relationship to other genes is unknown in the equine conceptus.
Mariana Diel de Amorim, Claudia Klein, Robert Foster, Lynn Dong, Maria Fernanda Lopez-Rodriguez, Claire Card   +5 more
doaj   +1 more source