Results 31 to 40 of about 1,752 (108)

Urinary aminopeptidase activities as early and predictive biomarkers of renal dysfunction in cisplatin-treated rats. [PDF]

open access: yesPLoS ONE, 2012
This study analyzes the fluorimetric determination of alanyl- (Ala), glutamyl- (Glu), leucyl-cystinyl- (Cys) and aspartyl-aminopeptidase (AspAp) urinary enzymatic activities as early and predictive biomarkers of renal dysfunction in cisplatin-treated ...
Andrés Quesada   +8 more
doaj   +1 more source

Grape Exosome-Like Nanovesicles Reverse the Prediabetic State in Mice. [PDF]

open access: yesJ Diabetes Res
Objective This research explored the effect of grape exosome–like nanovesicles (GELNs) on reversing prediabetic conditions in mice and investigated the underlying mechanisms via metabolomic and gut microbiota analyses. Methods Twenty‐four C57BL/6J mice were divided into four groups: normal control, prediabetic model, GELN intervention, and nutrient ...
Liu ZL   +5 more
europepmc   +2 more sources

Determination of the species among mitis group of genus Streptococus using a molecular identification key [PDF]

open access: yesZbornik Matice Srpske za Prirodne Nauke, 2012
We analyzed the gene order conservation among the species of genus Streptococcus and based on this we developed a molecular identification key. The identification key was not made up based on the genes’ amino acid or nucleotide sequences but on the ...
Kanjo Ištvan L.
doaj   +1 more source

Leucyl and Cystinyl Aminopeptidase as a Prognostic-Related Biomarker in OV Correlating with Immune Infiltrates

open access: yesPharmacogenomics and Personalized Medicine, 2023
Qian Ma,1,* Lei Chang,2,* Wenwen Wang,2,* Lingyi Che,1 Xiaoqin Song,3 Gailing Li,2 Ying Zhang,2 Yibing Chen,1 Zhuoyu Gu,4 Xin Ge5 1Genetics and Prenatal Diagnosis Center, First Affiliated Hospital, Zhengzhou University, Zhengzhou, 450052 ...
Ma Q   +9 more
doaj  

Wildfire strengthens the relationship between soil biodiversity and ecosystem multifunctionality in subtropical forests

open access: yesFunctional Ecology, Volume 40, Issue 5, Page 1415-1427, May 2026.
Read the free Plain Language Summary for this article on the Journal blog. Abstract Wildfires are disrupting and regenerating forces in nature that affect all ecosystem components. However, the impact of wildfires on soil multitrophic biodiversity and the resulting consequences for ecosystem multifunctionality (EMF) remain poorly understood.
Juan Zhou   +6 more
wiley   +1 more source

TrpM, a Small Protein Modulating Tryptophan Biosynthesis and Morpho-Physiological Differentiation in Streptomyces coelicolor A3(2). [PDF]

open access: yesPLoS ONE, 2016
In the model actinomycete Streptomyces coelicolor A3(2), small open reading frames encoding proteins with unknown functions were identified in several amino acid biosynthetic gene operons, such as SCO2038 (trpX) in the tryptophan trpCXBA locus.
Emilia Palazzotto   +9 more
doaj   +1 more source

A leucine aminopeptidase is involved in kinetoplast DNA segregation in Trypanosoma brucei.

open access: yesPLoS Pathogens, 2017
The kinetoplast (k), the uniquely packaged mitochondrial DNA of trypanosomatid protists is formed by a catenated network of minicircles and maxicircles that divide and segregate once each cell cycle.
Priscila Peña-Diaz   +4 more
doaj   +1 more source

Mechanisms of Aristolochic Acid Resistance in Specialist Butterflies and Evolutionary Insights for Potential Protective Pathways

open access: yesAdvanced Science, Volume 13, Issue 19, 2 April 2026.
The study provides an extreme example of insect adaptation to highly toxic defenses of host plants, and investigates the complex strategies to resist carcinogenic aristolochic acids, including physical isolation, metabolic detoxification, and DNA repair.
Yang Luan   +20 more
wiley   +1 more source

Microbial Resistance and Resilience to Short‐Term Drought Varies Among Grasslands Spanning a Broad Precipitation Gradient

open access: yesGrass and Forage Science, Volume 81, Issue 2, April-June 2026.
ABSTRACT Drought is increasing in severity and duration across the United States, particularly in arid and semi‐arid regions. Previous research has shown that drought has strong impacts in drier versus more mesic regions for aboveground productivity.
Leena L. Vilonen   +3 more
wiley   +1 more source

Effects of melatonin and metformin in preventing lysosome-induced autophagy and oxidative stress in rat models of carcinogenesis and the impact of high-fat diet

open access: yesScientific Reports, 2022
Imbalanced glucose tolerance and insulin resistance remain important as high cancer risk factors. Metformin administration to diabetic patients may be associated with a reduced risk of malignancy.
Natalia Kurhaluk, Halyna Tkachenko
doaj   +1 more source

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