A Common Genetic Background for Psoriasis and Cardiovascular Diseases: A Narrative Review. [PDF]
ABSTRACT Background and Aims Psoriasis is an immune‐mediated disease affecting primarily the skin and joints, but which also has systemic implications. There are assumptions about a common genetic background between psoriasis and cardiovascular diseases.
Lazar AL +9 more
europepmc +2 more sources
An unexpected role for leucyl aminopeptidase in UV tolerance revealed by a genome-wide fitness assessment in a model cyanobacterium. [PDF]
Weiss EL +6 more
europepmc +2 more sources
Chagas disease, caused by the kinetoplastid parasite Trypanosoma cruzi, is a human tropical illness mainly present in Latin America. The therapies available against this disease are far from ideal. Proteases from pathogenic protozoan have been considered
Jorge González-Bacerio +8 more
doaj +1 more source
Molecular characterization of a puromycin‐insensitive leucyl‐specific aminopeptidase, PILS‐AP [PDF]
The family M1 of Zn‐dependent aminopeptidases comprises members of closely related enzymes which are known to be involved in a variety of physiologically important processes. On the basis of two highly conserved peptide motifs, we have identified a new member of this family by PCR amplification and cDNA‐library screening.
L, Schomburg +3 more
+7 more sources
Salt Priming as a Smart Approach to Mitigate Salt Stress in Faba Bean (Vicia faba L.)
The present investigation aims to highlight the role of salt priming in mitigating salt stress on faba bean. In the absence of priming, the results reflected an increase in H2O2 generation and lipid peroxidation in plants subjected to 200 mM salt shock ...
Amira K. Nasrallah +4 more
doaj +1 more source
Urinary aminopeptidase activities as early and predictive biomarkers of renal dysfunction in cisplatin-treated rats. [PDF]
This study analyzes the fluorimetric determination of alanyl- (Ala), glutamyl- (Glu), leucyl-cystinyl- (Cys) and aspartyl-aminopeptidase (AspAp) urinary enzymatic activities as early and predictive biomarkers of renal dysfunction in cisplatin-treated ...
Andrés Quesada +8 more
doaj +1 more source
The major leucyl aminopeptidase of Trypanosoma cruzi (LAPTc) assembles into a homohexamer and belongs to the M17 family of metallopeptidases. [PDF]
Cadavid-Restrepo G +13 more
europepmc +2 more sources
The monoclonal antibody ER-BMDM1 recognizes a macrophage and dendritic cell differentiation antigen with aminopeptidase activity [PDF]
Here we describe the reactivity of monoclonal antibody (mAb) ER-BMDM1, directed against a 160-kDa cell membrane-associated antigen (Ag) with aminopeptidase activity.
Ewijk, W. (Willem) van +4 more
core +7 more sources
Heterotrophic microorganisms in marine sediments produce extracellular enzymes to hydrolyze organic macromolecules, so their products can be transported inside the cell and used for energy and growth. Therefore, extracellular enzymes may mediate the fate
Jenna M. Schmidt +4 more
doaj +1 more source

