Results 211 to 220 of about 253,634 (313)

Disparities in blood cancer survival in the UK 2009-2019: national cohort studies. [PDF]

BJC Rep
Hoang J, Allen J, Capel R, Thomas R, Smits S, Ahmed R, Webb H, Sheikh A, Cox S, Bygrave C, Hippisley-Cox J.   +10 more
europepmc   +1 more source

Phenylbutazone and Leukaemia [PDF]

BMJ, 1960
openaire   +2 more sources

Macrophage Extracellular Traps in Immunity and Cancer

Advanced Science, EarlyView.
As a macrophage‐mediated innate defense mechanism, the dysregulated release of METs drives chronic inflammation and influences tumor progression. Furthermore, METs exhibit a functional duality within the tumor microenvironment, capable of both promoting and suppressing tumor development.
Junyao Li, Eugenie Nepovimova, Adam Grundel, Lukas Peter, Qinghua Wu, Kamil Kuca   +5 more
wiley   +1 more source

Back pain in an adolescent: not just a sore spine! [PDF]

Ecancermedicalscience
Richard BM, Cholachagudda SS, Priya P, Totadri S, Srinivasan R.   +4 more
europepmc   +1 more source

RENAL‐CHIP: Rejection Evaluation via Non‐Invasive Analysis of Circulating Podocytes With Herringbone‐Chip Isolation Platform

Advanced Science, EarlyView.
RENAL‐CHIP converts 1 mL of peripheral blood into a biopsy‐equivalent readout of renal‐allograft fate. By magnetic capture and release of donor‐derived circulating podocytes through a herringbone microfluidic chip, 84% capture, 96% release and single‐cell RNA evidence of rejection‐specific immunity are achieved.
Juan Song, Yilong Liu, Zeyuan Zheng, Ming Zhu, Yuning Zou, Pei Liu, Yue Zheng, Xiyuan Yu, Jianzhong Zheng, Chen Shao, Huimin Zhang, Chaoyong Yang   +11 more
wiley   +1 more source

Targeting BCL-xL in Myeloid Malignancies: From Inhibitors to PROTAC. [PDF]

J Cell Mol Med
Cilloni D, Ferrando A, Frassoni F.
europepmc   +1 more source

T Cell Exhaustion in Cancer Immunotherapy: Heterogeneity, Mechanisms, and Therapeutic Opportunities

Advanced Science, EarlyView.
T cell exhaustion limits immunotherapy efficacy. This article delineates its progression from stem‐like to terminally exhausted states, governed by persistent antigen, transcription factors, epigenetics, and metabolism. It maps the exhaustion landscape in the TME and proposes integrated reversal strategies, providing a translational roadmap to overcome
Yang Yu, Xiaoyu Yao, Qingyang Wang, Mengrui Yang, Runze Li, Jiangjiang Qin, Jing Zhuang, Changgang Sun   +7 more
wiley   +1 more source

Impact of an early warning system on the outcome of patients with haematological malignancies receiving high-dose chemotherapy with or without haematopoietic cell transplantation: a protocol of the ALHERT cluster randomised trial. [PDF]

BMJ Open
Taillantou-Candau M, Kouatchet A, Darsonval A, Monmousseau F, Darras E, Schmidt A, Riou J, Orvain C.   +7 more
europepmc   +1 more source

NUDT21 Drives T‐Cell Acute Lymphoblastic Leukemia Through Dual Regulation of Alternative Polyadenylation and Transcriptional Activation

Advanced Science, EarlyView.
In summary, our study defines a coordinated oncogenic model in which NUDT21 integrates alternative polyadenylation–dependent UBE2D3 stabilization and transcriptional activation to sustain MYC‐driven T‐ALL cell survival, thereby establishing NUDT21 as a central regulatory node and a promising therapeutic target.
Conglian Qiu, Jianwei Wang, Zhiheng Li, Qi Ji, Hui Zhang, Qinyi Zhang, Senlin Zhang, Juanjuan Yu, Yanfang Tao, Yijun Wu, Chunxia Shi, Zong Zai, Zimu Zhang, Yizhen Li, Zhenjiang Bai, Shaoyan Hu, Jian Pan, Yang Yang, Shuiyan Wu   +18 more
wiley   +1 more source

Cost-effectiveness of cancer interventions in Rwanda: literature review and expert elicitation for health benefits package design. [PDF]

BMJ Public Health
Nemzoff C, Madriz-Montero A, Mumukunde I, Sindambiwe JMV, de Valois Ndishimye I, Uyisabye V, Humuza J, Baltussen R, Hitimana R, Sweeney S, Matutina Umuhoza S, Vassall A.   +11 more
europepmc   +1 more source