Results 161 to 170 of about 115,960 (309)

Microenvironmental Influences and Antigenic Stimulation in Chronic Lymphocytic Leukemia [PDF]

Hiddemann, Wolfgang, Seiler, Till
core   +1 more source

In Utero HSC Transplantation for Sickle Cell Disease: A Potential Therapeutic Approach That Overcomes Complications of Current Therapies

Prenatal Diagnosis, EarlyView.
ABSTRACT Sickle cell disease (SCD) affects millions worldwide but has limited treatment options, most of which carry significant side effects. At present, the only curative treatment for SCD is allogeneic or gene‐modified autologous hematopoietic stem cell (HSC) transplantation (Tx).
Oluwaseun O. Babatunde, Madeleine G. Bibby, Anthony Atala, Graça Almeida‐Porada, Christopher D. Porada   +4 more
wiley   +1 more source

Successful Treatment of Evans Syndrome Onset With Zanubrutinib in Combination With Romiplostim During Venetoclax Treatment in a Patient With Chronic Lymphocytic Leukemia: A Case Report. [PDF]

Clin Case Rep
Innao V, Barbagallo APM, Bianco O, Leotta V, Consoli U.   +4 more
europepmc   +1 more source

Semi‐mechanistic population PK/PD model to aid clinical understanding of myelodysplastic syndromes following treatment with Venetoclax and Azacitidine

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 448-459, March 2025.
Abstract Myelodysplastic syndromes (MDS) represent a group of bone marrow disorders involving cytopenias, hypercellular bone marrow, and dysplastic hematopoietic progenitors. MDS remains a challenge to treat due to the complex interplay between disease‐induced and treatment‐related cytopenias.
Neha Thakre, Corinna Maier, Jiuhong Zha, Benjamin Engelhardt, Johannes E. Wolff, Sven Mensing   +5 more
wiley   +1 more source

Ashwagandha: Is It Safe? Part 2: A Preclinical Evidence Review

Phytotherapy Research, EarlyView.
ABSTRACT The preclinical evidence for the safety of ashwagandha (Withania somnifera (L.) Dunal, AS) is reviewed, and its preparations (extracts) and constituents, from the general toxicity in animal models to in vitro and cell culture studies, which may elucidate mechanisms of action and explain clinical case reports.
Elizabeth M. Williamson, Thomas Brendler
wiley   +1 more source

Novel BTK inhibitors and degraders for relapsed/refractory CLL/SLL: latest updates from ASH 2025 annual meeting. [PDF]

J Hematol Oncol
Sharma P, Jiang H, Liu D.
europepmc   +1 more source

Rational Design and Development of Organic Afterglow Nanoparticles for Image‐Guided Interventions

Small Methods, EarlyView.
This review outlines the rational design, synthesis, and standardized characterization of organic afterglow nanoparticles for biomedical imaging and therapy. Mechanistic insights into chemically initiated electron exchange luminescence and reactive oxygen species‐mediated processes are connected to molecular engineering and nanoparticle fabrication ...
Asma Harun, Isabella Vasquez, Hannah Bowman, Robert Posey, Zhongkui Hong, Joshua Tropp, Indrajit Srivastava   +6 more
wiley   +1 more source

Using period analysis to timely provide serial data on long-term survival for patients with hematological malignancies from Taizhou, Eastern China. [PDF]

Front Oncol
Mo X, Bing X, Hua L, Xu C, Lei R, Chen X, Song Y, Chen T.   +7 more
europepmc   +1 more source

Peptide‐directed nanovehicles enabling tumor‐selective ROS amplification and antitumor immunity

VIEW, EarlyView.
Cancer cells are vulnerable to oxidative stress, yet exploit immune tolerance to escape destruction. In contrast, their metabolic profile is markedly altered to support rapid proliferation, accompanied by elevated production of reactive oxygen species (ROS).
Manuela Calin, Galyna Bila, Ileana Manduteanu, Rostyslav Bilyy   +3 more
wiley   +1 more source

A Rare Case of Concurrent Chronic Lymphocytic Leukemia and Therapy-Unrelated Acute Myeloid Leukemia That Evolved From Myelodysplastic Neoplasm. [PDF]

Cureus
Bansil S, Lai SY, Lo AE, Dietz R, Reed JP.   +4 more
europepmc   +1 more source