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Concomitant L248V With E225V Mutation in the BCR-ABL Gene Associated With Rapid Chronic Myeloid Leukemia Lymphoid Blast Crisis. [PDF]

Cureus
Chronic myeloid leukemia (CML) is a myeloproliferative neoplasm characterized by the presence of the Philadelphia chromosome (Ph), resulting from the t(9;22)(q34;q11.2) translocation.
Tungjitviboonkun S, Wachirapornpruet P, Unsuwan S.   +2 more
europepmc   +2 more sources

Causal association between endocrine diseases and lymphoid malignancies explored through two-sample Mendelian randomization analysis [PDF]

Scientific Reports
Endocrine diseases are suspected contributors to lymphoid malignancies, but their precise association is unclear. This study aimed to investigate the causal relationship between various endocrine diseases—specifically type 2 diabetes, obesity, diabetic ...
Chenze Zhao, Yu Zhang, Lili Qian, Qing Guo, Ni Zhu   +4 more
doaj   +2 more sources

Prognostic Factors and Survival Outcomes by Disease Subtypes in a Cohort of Iranian Patients with acute leukemia [PDF]

Reviews in Clinical Medicine, 2023
Introduction: Studying the survival factors of leukemia patients can lead to a reduction in healthcare costs. This study aimed to evaluate the survival rate and potential predictive factors in leukemia patients in northeast Iran.Methods: Baseline ...
Sahar Ravanshad, Zahra Fahimian, Parsa Shoghi, Ali Moradi, Valareza Alizadeh, Negar Javdan, Hassan Mehrad-Majd   +6 more
doaj   +1 more source

Targeting Bruton’s Tyrosine Kinase in CLL

Frontiers in Immunology, 2021
Targeting the B-cell receptor signaling pathway through BTK inhibition proved to be effective for the treatment of chronic lymphocytic leukemia (CLL) and other B-cell lymphomas.
Inhye E. Ahn, Jennifer R. Brown
doaj   +1 more source

Weight status in survivors of childhood acute lymphocytic leukemia in South Korea: a retrospective descriptive study [PDF]

Child Health Nursing Research, 2023
Purpose This study investigated weight status in survivors of childhood acute lymphocytic leukemia (ALL) and identified related factors. Methods A retrospective review of the electronic medical records of survivors of childhood ALL (n=230) was conducted.
Yeongseon Kim, Kyung-Sook Bang
doaj   +1 more source

The 5th edition of the World Health Organization Classification of Haematolymphoid Tumours: Lymphoid Neoplasms

Leukemia, 2022
We herein present an overview of the upcoming 5th edition of the World Health Organization Classification of Haematolymphoid Tumours focussing on lymphoid neoplasms.
R. Alaggio, Catalina Amador, I. Anagnostopoulos, A. Attygalle, I. Araújo, E. Berti, G. Bhagat, A. Borges, Daniel Boyer, M. Calaminici, A. Chadburn, J. C. Chan, W. Cheuk, W. Chng, J. Choi, S. Chuang, S. Coupland, M. Czader, S. Dave, D. de Jong, M. Du, K. Elenitoba-Johnson, J. Ferry, J. Geyer, D. Gratzinger, J. Guitart, S. Gujral, M. Harris, C. Harrison, S. Hartmann, A. Hochhaus, P. Jansen, K. Karube, W. Kempf, J. Khoury, H. Kimura, W. Klapper, Alexandra E. Kovach, Shaji K. Kumar, A. Lazar, S. Lazzi, L. Leoncini, N. Leung, Vasiliki Leventaki, Xiao-Qiu Li, M. Lim, Wei-ping Liu, A. Louissaint, Andrea N Marcogliese, L. Medeiros, M. Michal, R. Miranda, C. Mitteldorf, S. Montes-Moreno, W. Morice, V. Nardi, K. Naresh, Y. Natkunam, S. Ng, I. Oschlies, G. Ott, M. Parrens, M. Pulitzer, S. Rajkumar, A. Rawstron, Karen Rech, A. Rosenwald, Jonathan Said, C. Sarkozy, S. Sayed, C. Saygin, Anna Schuh, William Sewell, R. Siebert, A. Sohani, R. Tooze, A. Traverse-Glehen, F. Vega, B. Vergier, A. Wechalekar, Brent Wood, L. Xerri, Wenbin Xiao   +82 more
semanticscholar   +1 more source

Outcome of patients with chronic myeloid leukemia in lymphoid blastic phase and Philadelphia chromosome–positive acute lymphoblastic leukemia treated with hyper‐CVAD and dasatinib

Cancer, 2021
Dasatinib monotherapy has demonstrated modest clinical activity in chronic myeloid leukemia in lymphoid blastic phase (CML‐LBP). The outcome of Philadelphia chromosome (Ph)–positive acute lymphoblastic leukemia (ALL) has dramatically improved with ...
Kiyomi Morita, H. Kantarjian, K. Sasaki, G. Issa, N. Jain, M. Konopleva, N. Short, Koichi Takahashi, C. Dinardo, T. Kadia, G. Garcia-Manero, N. Daver, Guillermo Montalban Bravo, J. Cortes, F. Ravandi, E. Jabbour   +15 more
semanticscholar   +1 more source

Two Cases of Chronic Myeloid Leukemia in Lymphoid Blast Phase Presented as Philadelphia-Positive Acute Lymphoblastic Leukemia

Clinical Pediatric Hematology-Oncology, 2023
Patients with chronic myeloid leukemia (CML) in lymphoid blast phase can present clinical characteristics resembling Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph+ ALL).
Tae Hoon Lee, Hee Young Ju, Ji Won Lee, Ki Woong Sung, Keon Hee Yoo   +4 more
doaj   +1 more source

Spectrum of immunophenotypic aberrancies in acute leukemia along with their correlation with adverse hematological parameters

Indian Journal of Health Sciences and Biomedical Research KLEU, 2022
BACKGROUND: The identification of aberrant phenotypes in acute leukemia is crucial for treatment monitoring and minimal residual disease analysis.
Sana Ahuja, Avneesh Malviya
doaj   +1 more source

The 2016 revision to the World Health Organization classification of myeloid neoplasms and acute leukemia.

Blood, 2016
The World Health Organization (WHO) classification of tumors of the hematopoietic and lymphoid tissues was last updated in 2008. Since then, there have been numerous advances in the identification of unique biomarkers associated with some myeloid ...
D. Arber, A. Orazi, R. Hasserjian, J. Thiele, M. Borowitz, M. L. Le Beau, C. Bloomfield, M. Cazzola, J. Vardiman   +8 more
semanticscholar   +1 more source