Results 231 to 240 of about 159,104 (312)

Putative Clonal Evolution in a PHF6‐Mutant T/NK‐Cell Lymphoproliferative Disorder With Selective Loss of a STAT5B‐Mutant Subclone

eJHaem, Volume 7, Issue 3, June 2026.
Mark Anthony Turingan, Cuihong Wei, Nihad Almokhtar, Abi Vijenthira, Hong Chang   +4 more
wiley   +1 more source

GATA2 Mutations Predict Poor Prognosis in Transplanted Myeloid Neoplasms

Cancer Medicine, Volume 15, Issue 5, May 2026.
ABSTRACT Background GATA binding protein 2 (GATA2) plays a crucial role in the differentiation, proliferation, and maintenance of hematopoietic stem cells (HSCs). GATA2 mutations have been identified in acute myeloid leukemia (AML) and myelodysplastic syndromes (MDS), but the impact of somatic GATA2 mutations on prognosis remains controversial ...
Xian Zhang, Bingjie Wang, Yujun Dong, Qingya Wang, Qian Wang, Jialin Zhu, Qingyun Wang, Na Han, Yuan Li   +8 more
wiley   +1 more source

Case Report: Co-existence of <i>BCR::PDGFRA</i> gene fusion and <i>PDGFRA</i> variants in myeloid neoplasm with persistent leukocytosis, large splenomegaly, and eosinophilia. [PDF]

Front Oncol
Xiao Z, Lu C, Zhang P, Han N, He X, Zhang J, Feng Y, Guan M, Ouyang L, Gao Y, Li Y.   +10 more
europepmc   +1 more source

Progressive Rapid Atherosclerotic Plaque Formation and Early Stent re‐Stenosis in an Untreated CLL Patient; A Case Report

Clinical Case Reports, Volume 14, Issue 5, May 2026.
ABSTRACT A 66 year‐old male with a history of hypertension and poor follow‐up for chronic lymphocytic leukemia (CLL) experienced two episodes of non‐ST elevation myocardial infarction (NSTEMI) within a 6 month period. Initial coronary angiography showed two‐vessel disease, and percutaneous coronary intervention (PCI) was performed on the left anterior ...
Mohammad Shojae, Hosseinali Rostamipour, Aref Ghanaatpisheh, Sepehr Ramezanipour, Nikta Heidari   +4 more
wiley   +1 more source

Spatial analysis of residential location at birth, PFAS in public water, and childhood cancers in Southern California (2000-2019). [PDF]

J Expo Sci Environ Epidemiol
Binczewski NR, Morimoto LM, Wiemels JL, Richardson DB, Bartell SM, Metayer C, Vieira VM.   +6 more
europepmc   +1 more source

Targeting the nuclear export receptor exportin‐1 in acute myeloid leukaemia: From biology to clinical translation

Clinical and Translational Medicine, Volume 16, Issue 5, May 2026.
• XPO1 hyperactivation promotes leukaemogenesis by altering nucleocytoplasmic transport and transcriptional control in acute myeloid leukaemia (AML). • Selinexor and eltanexor show preferential activity in NPM1‐mutated, DEK::NUP214‐positive and SF3B1‐mutated myeloid neoplasms.
Yifan Liu, Xiaoya Yun, Weidong Ding, Suxiao Li, Hui Liu   +4 more
wiley   +1 more source

Integrating Rapid Lymphoma Next-Generation Sequencing Panel-Based Testing into Routine Genomic Diagnostics. [PDF]

Ann Lab Med
Shin S, Lee ST.
europepmc   +1 more source

In vivo CAR therapies: Turning the patient into their own CAR factory

HemaSphere, Volume 10, Issue 5, May 2026.
Abstract Over the past decade, ex vivo autologous chimeric antigen receptor (CAR)‐T‐cell therapies have reshaped the treatment of B‐cell malignancies. Despite their remarkable clinical efficacy, their application remains limited by complex manufacturing processes, demanding logistics, long turnaround times, and substantial costs. In vivo CAR approaches
François Vilcot, Carole‐Anne Brugère, Jaime Fuentealba, Roch Houot   +3 more
wiley   +1 more source

Successful Haplo-Hematopoietic Stem Cell Transplantation for Juvenile Myelomonocytic Leukemia in a Child With Underlying Thrombocytopenia-Absent Radius Syndrome: A Unique Case. [PDF]

Cancer Rep (Hoboken)
Sharidah SA, Elhussien A, Soliman WIA, Ellithy NI.   +3 more
europepmc   +1 more source

Chronic lymphocytic leukemia with IGH::BCL3‐translocation is characterized by a homogeneous and distinct genetic and epigenetic landscape

HemaSphere, Volume 10, Issue 5, May 2026.
Abstract Approximately 1% of chronic lymphocytic leukemia (CLL) cases harbor a translocation juxtaposing the immunoglobulin heavy chain (IGH) and B‐cell lymphoma 3 (BCL3) loci. Aiming at comprehensive molecular characterization of IGH::BCL3‐positive B‐cell neoplasms, we here investigated samples from 84 patients using fluorescence in situ hybridization
Cosima Drewes, Cristina López, Juan Emilio Martinez‐Manjón, Nnamdi Okeke, Billy Jebaraj, Susanne Bens, Björn Brändl, Martin J. S. Dyer, Barbara Eichhorst, Anja Fischer, Kirsten Fischer, Sandra Robrecht, Michael Hallek, Selina Glaser, Sina Hillebrecht, Sandrine Jayne, Helene Kretzmer, Anja Mottok, Franz‐Josef Müller, Christof Schneider, Ole Ammerpohl, Coral del Val, Stephan Stilgenbauer, Eugen Tausch, Reiner Siebert   +24 more
wiley   +1 more source