Results 221 to 230 of about 388,053 (254)

Rare CNS manifestation of high-risk CLL with excellent response to triplet targeted therapy. [PDF]

Leuk Res Rep
Swaminathan A, Nathany S, Singh S, Gupta A, Sen IB, Garg P, Kothari A, Verma K, Dua V, Bhargava R.   +9 more
europepmc   +1 more source

Ineffectiveness of immune checkpoint inhibitors in prostate cancer: is it just a question of ‘‐mabs’?

The Journal of Pathology, Volume 270, Issue 2, Page 139-162, October 2026.
Abstract Prostate cancer (PCa) is the second most common type of neoplasm, currently treated with a variety of therapeutic agents. Although advances in treatment over the past decade have improved overall survival, patients with advanced PCa eventually progress from hormone‐sensitive PCa to metastatic castration‐resistant PCa.
Giuseppe Schepisi, Irene Torresan, Emilio Francesco Giunta, Sara Bleve, Nicole Brighi, Elisa Tassinari, Sofia Zanuccoli, Maria Concetta Cursano, Cristian Lolli   +8 more
wiley   +1 more source

Cross‐Talk Between Histamine H2 Receptor and Glucocorticoid Receptor: Potential Implications in Acute Myeloid Leukemia Treatment

Pharmacology Research &Perspectives, Volume 14, Issue 5, October 2026.
ABSTRACT This study investigates the impact of histamine H2 receptor activation on glucocorticoid receptor (GR)‐mediated transcriptional activity, as well as its effects on leukemic cell proliferation and chemotherapy resistance. We demonstrate that activation of the histamine H2 receptor by its specific agonist, amthamine, enhances GR transcriptional ...
Valeria Torralba‐Agu, Natalia Fernández, Carina Shayo, Carlos Davio, C. Daniel Zappia, Federico Monczor   +5 more
wiley   +1 more source

PU.1 as a Master Regulator of Immune Cell Development and Function: Structural Basis, Gene Regulatory Networks, Disease Roles, and Therapeutic Targeting. [PDF]

Biology (Basel)
Ramani M, Nguyen N, Solis J, Tenen DG, Trinh BQ.   +4 more
europepmc   +1 more source

Piper nigrum Has an Antitumor Effect Through Regulation of the Phosphatidylinositol 3‐Kinase Signaling Pathway in a Murine Model of Acute Myeloid Leukemia

Phytotherapy Research, Volume 40, Issue 10, Page 5988-6004, October 2026.
Overview of the antileukemic effects of Piper nigrum extract in AML. P. nigrum reduced leukemic cell proliferation and glycolytic metabolism through modulation of the PI3K/AKT/mTOR pathway. In vivo, treatment reduced leukemic burden, improved hematological parameters, prolonged survival, and modulated antitumor immune responses.
Natalia Murillo, Paola Lasso, Claudia Urueña, Susana Fiorentino   +3 more
wiley   +1 more source

Introduction to the Review Series. Chronic myeloid leukemia in 2026. [PDF]

Haematologica
Radich J.
europepmc   +1 more source

Persistent SARS‐CoV‐2 RNA Positivity in a Chronic Lymphocytic Leukaemia Patient for 127 Days After Disease Onset: A Case Report

Respirology Case Reports, Volume 14, Issue 10, October 2026.
This case report presents a 69‐year‐old woman with chronic lymphocytic leukaemia who exhibited prolonged SARS‐CoV‐2 RNA positivity for 127 days despite standard treatments. This case emphasises the profound immunodeficiency in CLL patients and highlights the necessity for tailored therapeutic strategies to manage persistent COVID‐19 infections ...
Farnoosh Khamseh, Amir‐Hossein Moghtader‐Mojdehi, Zahra Nemati, Mehrdad Haghighi   +3 more
wiley   +1 more source

Deregulation of FOXF1/FENDRR from t(14;16)(q32;q24) defines a subtype of high-risk lineage ambiguous leukemia. [PDF]

Blood
Di Giacomo D, Pölönen P, Bardelli V, Kimura S, Pierini V, Pagliaro L, Arniani S, Chang Y, Gao Q, Montefiori LE, Wu Y, Park CS, Wright WC, Vento F, Wei H, Matteucci C, Lei S, Rosikiewicz W, Nardelli C, Lema Fernandez AG, Østergaard A, Backhaus Wagner EA, Baviskar P, Cerrano M, Leocin M, Manabe A, Hirabayashi S, Takita J, Hasegawa D, Miyamoto S, Macchiarulo A, Xu J, Teachey DT, Roti G, Iacobucci I, La Starza R, Mecucci C, Mullighan CG.   +37 more
europepmc   +1 more source

Timing is everything: age-dependent cancer risk in RUNX1-FPD. [PDF]

Blood Adv
Cantor AB, Shimamura A.
europepmc   +1 more source

PKC isoforms in hematopoietic lineages and myeloid/lymphoid leukemias: mechanistic insights and therapeutic prospects. [PDF]

Front Oncol
Wang X, Wang C, Li S, Zhang K, Liu A, Deng X, Bian Q, Lu S, Sima J.   +8 more
europepmc   +1 more source