Results 241 to 250 of about 689,537 (284)

CD200 in acute myeloid leukemia: marked upregulation in CEBPA biallelic mutated cases. [PDF]

Diagn Pathol
González-Guerrero L, Castellet H, Martínez C, González N, Guijarro F, Lloveras N, Pratcorona M, Gich I, Berenguer-Molins P, Perera-Bel J, Zamora L, Mascaró M, Sampol A, Garcia-Guiñón A, Vives S, Tormo M, Arnan M, Villamor N, Nomdedéu JF.   +18 more
europepmc   +1 more source

Integrative cytogenetic and molecular studies unmask "chromosomal mimicry" in hematologic malignancies. [PDF]

Blood Adv
Zhao M, Ryall S, Brody SJ, Harris AC, Cabral K, Brownstein C, Kim JC, Smith AC, Dal Cin P, Narayan R, Sikkink K, Schmitt A, Hobbs GS, Fathi AT, Griffin GK, Sait SNJ, Iafrate AJ, Aster JC, Graubert TA, Nardi V, Dubuc AM.   +20 more
europepmc   +1 more source

Advancements in genetic analysis: Insights from a case study and review of next‐generation sequencing techniques for veterinary oncology applications

Veterinary Clinical Pathology, EarlyView.
Abstract Acute myeloid leukemia (AML) poses significant challenges in veterinary medicine, with limited treatment options and poor survival rates. While substantial progress has been made in characterizing human AML, translating these advancements to veterinary practice has been hindered by limited molecular understanding and diagnostic tools. The case
R. Adam Harris, Jillian Nolan, Dylan Ammons, Samantha Beeson, Douglas Thamm, Anne Avery   +5 more
wiley   +1 more source

European Cancer Organisation Essential Requirements for Quality Cancer Care: Hematological malignancies. [PDF]

Hemasphere
Gribben JG, Quintanilla-Martinez L, Crompton S, Arends J, Bardin C, Becker H, Castinetti F, Csaba DL, D'Anastasi M, Frese T, Geissler J, Matuzeviciene R, Mayerhoefer ME, Medeiros R, Morgan K, Narbutas Š, Nier S, Ricardi U, Arjona ET, Ungan M, Warwick L, Zucca E.   +21 more
europepmc   +1 more source

Management of T‐cell malignancies: Bench‐to‐bedside targeting of epigenetic biology

CA: A Cancer Journal for Clinicians, EarlyView.
Abstract The peripheral T‐cell lymphomas (PTCL) are the only disease for which four histone deacetylase (HDAC) inhibitors have been approved globally as single agents. Although it is not clear why the PTCL exhibit such a vulnerability to these drugs, understanding the biological basis for this activity is essential.
Ariana Sabzevari, Johnson Ung, Jeffrey W. Craig, Kallesh D. Jayappa, Ipsita Pal, David J. Feith, Thomas P. Loughran Jr, Owen A. O’Connor   +7 more
wiley   +1 more source

Waldenström Macroglobulinemia and Chronic Myelomonocytic Leukemia: Case Report and Literature Review. [PDF]

Onco Targets Ther
Pan Y, Wang Y, Wang Q.
europepmc   +1 more source

TP53‐Mutated Acute Myeloid Leukemia: Unanswered Questions

Hematological Oncology, Volume 43, Issue 4, July 2025.
ABSTRACT TP53‐mutated acute myeloid leukemia (AML) remains one of the most treatment‐resistant hematologic malignancies, with poor overall survival despite advancements in therapeutic strategies. The loss of functional p53 compromises DNA repair, apoptosis, and genomic stability, rendering both conventional and novel therapies largely ineffective. This
Antonella Bruzzese, Ernesto Vigna, Enrica Antonia Martino, Caterina Labanca, Giulio Caridà, Francesco Mendicino, Eugenio Lucia, Virginia Olivito, Noemi Puccio, Antonino Neri, Fortunato Morabito, Massimo Gentile   +11 more
wiley   +1 more source

Identification of leukemia-enriched signature through the development of a comprehensive pediatric single-cell atlas. [PDF]

Nat Commun
Mumme HL, Huang C, Ohlstrom D, Bakhtiari M, Raikar SS, DeRyckere D, Qayed M, Castellino SM, Wechsler DS, Porter CC, Graham DK, Bhasin SS, Bhasin M.   +12 more
europepmc   +1 more source

ILC2 Diversity, Location, and Function in Pulmonary Disease

Immunological Reviews, Volume 332, Issue 1, July 2025.
ABSTRACT Type‐2 inflammation is driven by the production of canonical type‐2 cytokines IL‐4, IL‐5, and IL‐13. Type‐2 cytokines promote mucus production, innate immune cell recruitment, and smooth muscle contractility in mucosal tissues. These hallmarks of type‐2 inflammation are important contributors to the weep‐and‐sweep responses observed in the ...
Mukesh Verma, Uryan I. Can, R. Lee Reinhardt   +2 more
wiley   +1 more source

Role of B-Cell Lymphoma/Leukemia 11A in Normal and Malignant Hematopoiesis. [PDF]

Biology (Basel)
Zhang H, Zeng J, Zhang F, Liu J, Liang L.   +4 more
europepmc   +1 more source