Results 121 to 130 of about 19,815 (203)
Genetic requirement for Ras in the transformation of fibroblasts and hematopoietic cells by the Bcr-Abl oncogene. [PDF]
To determine the functional importance of Ras in transformation by Abl oncogenes, we used a genetic approach to measure the effect of impaired Ras activity on the ability of Bcr-Abl or v-Abl to transform cells.
McLaughlin, J, Sawyers, CL, Witte, ON
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Plenary Abstracts Session & Oral Presentations
HemaSphere, Volume 9, Issue S1, June 2025.
wiley +1 more source
Philadelphia Chromosome-negative, bcr/abl-positive Chronic Myelogenous Leukemia.
K, Inokuchi, K, Dan
openaire +3 more sources
Молекулярно-генетическая диагностика минимальной остаточной болезни в онкогематологии [PDF]
лейкозГЕМАТОЛОГИЧЕСКИЕ НОВООБРАЗОВАНИЯГЕННАЯ ЭКСПРЕССИЯГЕНЕТИЧЕСКИЕ ...
Семенов, В. М. +1 more
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Although bcr-abl polymerase chain reaction (PCR) positivity after bone marrow transplantation (BMT) for chronic myelogenous leukemia (CML) is significantly related to relapse, the predictive value of the assay is not very high and therefore most investigators consider that qualitative RT-PCR data alone are too imprecise to enable clinical decisions to ...
J, Román +10 more
openaire +1 more source
Analysis of imatinib in bone marrow and plasma samples of chronic myeloid leukaemia patients using solid phase extraction LC-ESI-MS [PDF]
The LC-ESI-MS was developed and validated for the analysis of imatinib in plasma and bone marrow samples using deuterated imatinib (D(8)-IM) as an internal standard. The biological samples were extracted using Strata-X-C SPE cartridges and separated on C&
Elliott, M. +4 more
core +1 more source
New prognostic factors in chronic myeloid leukaemia
The tyrosine kinase inhibitor imatinib mesylate (IM) has proved a major advance in the management of patients with chronic myeloid leukaemia (CML) but about 15% of patients do not achieve complete cytogenetic responses (CCyR) (primary resistance) and a ...
Khorashad, Sorouri, Khorashad, Sorouri
core +1 more source
Cromossoma Philadelphia e leucemia : biologia e terapêutica [PDF]
Monografia realizada no âmbito da unidade de Estágio Curricular do Mestrado Integrado em Ciências Farmacêuticas, apresentada à Faculdade de Farmácia da Universidade de CoimbraA Leucemia Mielóide Crónica (LMC) é uma neoplasia caraterizada por uma ...
Martins, Sofia Vanessa Rodrigues
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