Lipidomic approach for stratification of Acute Myeloid Leukemia patients [PDF]
The pathogenesis and progression of many tumors, including hematologic malignancies is highly dependent on enhanced lipogenesis. De novo fatty-acid synthesis permits accelerated proliferation of tumor cells by providing structural components to build the membranes.
arxiv
Self-Supervised Multiple Instance Learning for Acute Myeloid Leukemia Classification [PDF]
Automated disease diagnosis using medical image analysis relies on deep learning, often requiring large labeled datasets for supervised model training. Diseases like Acute Myeloid Leukemia (AML) pose challenges due to scarce and costly annotations on a single-cell level.
arxiv
A tumor-immune model of chronic myeloid leukemia with optimal immunotherapeutic protocols [PDF]
The interactions between tumor cells and the immune system play a crucial role in cancer evolution. In this study, we explore how these interactions influence cancer progression by modeling the relationships among naive T cells, effector T cells, and chronic myeloid leukemia cells. We examine the existence of equilibria, the asymptotic stability of the
arxiv
Complete response of myeloid/lymphoid neoplasms with PDGFRA rearrangement presenting as leukemia/myeloid sarcoma to imatinib monotherapy. [PDF]
Ma R+5 more
europepmc +1 more source
Clinical Validation of a Real-Time Machine Learning-based System for the Detection of Acute Myeloid Leukemia by Flow Cytometry [PDF]
Machine-learning (ML) models in flow cytometry have the potential to reduce error rates, increase reproducibility, and boost the efficiency of clinical labs. While numerous ML models for flow cytometry data have been proposed, few studies have described the clinical deployment of such models.
arxiv
Reverse Degree-Based Topological Indices and QSPR Analysis of Cancer Drugs [PDF]
A topological index of a graph $G$ is a numerical quantity that describes its topology. Reverse degree-based topological indices play an important role in finding topological descriptors. Azacitidine, Decitabine, and Guadecitabine are hypomethylating agents which are used for the treatment of patients with higher-risk myelodysplastic syndromes, acute ...
arxiv
AKI in chronic myeloid leukemia: remember lysozyme-induced nephropathy. [PDF]
Santos A, Marques N, Pestana R.
europepmc +1 more source
The road not taken: Exploring non-transplant options in De Novo philadelphia positive acute myeloid leukemia. [PDF]
Sharif MI+6 more
europepmc +1 more source
A shadow in the treatment of acute leukemia: lineage switch. [PDF]
Zhou Q, Wang Y.
europepmc +1 more source
Assessment of chromatin remodeling of acute myeloid leukemia cells treated with gilteritinib: a case report. [PDF]
Mori J+6 more
europepmc +1 more source