Results 81 to 90 of about 509,494 (205)

Bone marrow endothelial cell-derived interleukin-4 contributes to thrombocytopenia in acute myeloid leukemia

open access: yesHaematologica, 2019
Normal hematopoiesis can be disrupted by the leukemic bone marrow microenvironment, which leads to cytopenia-associated symptoms including anemia, hemorrhage and infection.
Ai Gao   +10 more
doaj   +1 more source

TRANSMISSION OF MYELOID LEUKEMIA OF MICE [PDF]

open access: yesJournal of Experimental Medicine, 1934
A transmissible strain of myeloid leukemia of mice is described. It can be readily passed from diseased to healthy mice by the transfer of tissues that contain live cells; but inoculation fails when the latter are not present. Inoculation is successful in almost every mouse whose resistance is lowered by X-rays. It is often successful in
openaire   +2 more sources

A certified plasmid reference material for the standardisation of BCR-ABL1 mRNA quantification by real time quantitative PCR [PDF]

open access: yes, 2015
Serial quantification of BCR–ABL1 mRNA is an important therapeutic indicator in chronic myeloid leukaemia, but there is a substantial variation in results reported by different laboratories.
Mitterbauer, G.   +316 more
core   +3 more sources

Radotinib inhibits mitosis entry in acute myeloid leukemia cells via suppression of Aurora kinase A expression

open access: yesTumor Biology, 2019
Aurora kinases play critical roles in regulating several processes pivotal for mitosis. Radotinib, which is approved in South Korea as a second-line treatment for chronic myeloid leukemia, inhibits the tyrosine kinase BCR-ABL and platelet-derived growth ...
Sook-Kyoung Heo   +10 more
doaj   +1 more source

Acute Myeloid Leukemia [PDF]

open access: yesJournal of the National Comprehensive Cancer Network, 2011
Margaret R, O'Donnell   +19 more
openaire   +2 more sources

Stability and Bifurcation of the Immune Model of Chronic Myeloid Leukemia with Time Delay

open access: yesJournal of Harbin University of Science and Technology
In order to investigate the effects of the differentiation delay in chronic myeloid leukemia stem cells on the dynamic behaviors among chronic myeloid leukemia stem cells, chronic myeloid leukemia mature cells and effector T cells, a delayed immune ...
WANG Jingnan, SUN Yue
doaj   +1 more source

Classification of acute myeloid leukemia

open access: yesBLOOD RESEARCH, 2020
The World Health Organization (WHO) Classification of Tumors of Hematopoietic and Lymphoid Tissues was revised in 2017 on the basis of recent high-throughput sequencing and gene expression data on hematologic malignancies. This review explores the current WHO classification of acute myeloid leukemia (AML) and related precursor neoplasms, highlighting ...
openaire   +3 more sources

Lack of effect of the human GM-CSF analog E21R on the survival of primary human acute myeloid leukemia cells [PDF]

open access: yes, 2004
The granulocyte-macrophage colony-stimulating factor (GM-CSF) analog E21R binds to the GM-CSF receptor complex with low affinity and acts as a competitive antagonist.
Jakupovic, I.   +3 more
core  

Proteomic Identification of the MYST Domain Histone Acetyltransferase TIP60 as a Coactivator of the Myeloid Transcription Factor C/EBPα [PDF]

open access: yes, 2007
The transcription factor C/EBPα is a key player in granulopoiesis and leukemogenesis. In the present study, we sought to identify C/EBPα interacting proteins.
Bararia, Deepak
core   +1 more source

Characterisation of the role of KLF5 in normal haemopoiesis and acute myeloid leukaemia. [PDF]

open access: yes, 2011
Krüppel-like factor 5 (KLF5) encodes a zinc finger transcription factor involved in growth, differentiation and apoptosis of a number of different tissues, and it has previously been implicated as either a tumour suppressor or oncogene in various solid ...
Diakiw, Sonya
core  

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