Results 91 to 100 of about 838,442 (361)
A certified plasmid reference material for the standardisation of BCR-ABL1 mRNA quantification by real time quantitative PCR [PDF]
, 2015 Serial quantification of BCR–ABL1 mRNA is an important therapeutic indicator in chronic myeloid leukaemia, but there is a substantial variation in results reported by different laboratories.Mitterbauer, G., Kim, D.-W., S McCarron, Polakova, K.M., Hall, V, Preudhomme, C., K M Polakova, Hall, V., Schimmel, Heinz G., Cross, N.CP., L Foroni, Gerrard, G., Waits, Paula S., Cross, N.C.P., Jansson, Mattias,, Polakova, Km, Ozbek, U (Ugur), E O Leibundgut, El Housni, Hakim, R Ganderton, E Gineikienė, G Martinelli, Kizilors, A., White, H., Corbisier, P., Hayette, S, Colomer, D., Ganderton, R., Mueller, M. C., Kim, D-W, Van der Velden, V. H. J., de Lange, T, P Waits, Wilson, G., Mitterbauer Hohendanner, G, Cross, Nicholas C P., J Nomdedéu, Nagar, M, Nagar, M., Merle, P. A., Clench, T, Müller, M.C., Hochhaus, A., Fletcher, L, Deprez, Ludovic, Milner, B., Jurcek, Tomas, Nymoen, D. A., Andrikovics, H., T Sacha, Touloumenidou, Tasoula, Cayuela, J-M, Boeckx, N., Merle, Pauline A., Lange, T, Emons, H, Wang, L., Wang, L, D-W Kim, T Jurcek, Touloumenidou, T, Trapmann, Stefanie, A Aggerholm, Gineikiene, Eglė, Barbany, G., McCarron, S., V Kairisto, Mazoua, S., Schimmel, H, Polakova, K M, S Hayette, White, H, Barbany, G, H White, C Preudhomme, Cayuela, Jm, G Romeo, R Talmaci, Lin, Feng, K Zoi, Aggerholm, A, Lion, T, Akiki, S., Jurcek, T., Kairisto, V, A Kizilors, IZZO, BARBARA, Aggerholm, A., Van der Velden, Vh, Mueller, MC, F Lin, Colomer, D, Leibundgut, E O, Hochhaus, A, J Farrugia, Müller, Mc, Milner, B, G Mitterbauer-Hohendanner, Trapmann, S., Leibundgut, Eo, U Ozbek, Waits, P., Daraio, Filomena, Farrugia, J., Nomdedéu, J, Kizilors, Aytug, Preudhomme, C, Wilson, Gillian A., Ozbek, U, Lange, Thoralf, H Andrikovics, Andrikovics, H, El Housni, H, Emons, Hendrik, Deprez, L., Kim, Dong-Wook, Lin, F., Wilkinson, E., S Chudleigh, Dulucq, S., Schimmel, H., Izzo, B., D Colomer, Hayette, S., D Wren, Corbisier, Philippe, P Johnels, Cross, Nc, M Nagar, Zoi, K, V H J Van der Velden, N Boeckx, Bench, Anthony J., Aggerholm, Anni, El Housni, H., Gineikienė, E, H El Housni, Catherwood, M., Kairisto, Veli, Nagar, Meital, Catherwood, Mark Alexander, Hall, Victoria J., Wang, Lihui, Pfeifer, H, R Zadro, Milner, Benedict J., Nymoen, Dag André, Zadro, Renata, Leibundgut, E. O., Kim, Dw, S Trapmann, Fletcher, L., Kairisto, V., Daraio, F, Romeo, Giuliana, K Raudsepp, Akiki, S, Lin, F, L Wang, M Catherwood, Van der Velden, V.H.J., Dulucq, S, Wilson, G, M Jansson, Hochhaus, Andreas, Merle, P A, Nickless, Guillermina, Pajič, T, van der Velden, Vincent, Jansson, M, T Clench, Bench, A, Nomdedéu, Josep, T Touloumenidou, Universitat Autònoma de Barcelona. Departament de Medicina, Müller, M C, Deprez, L, Romeo, G, Foroni, L, Raudsepp, K, Mazoua, Stéphane, Wren, Dörte, Hayette, Sandrine, A Hochhaus, Machová Polakova, Katerina Machová, Foroni, L., Mitterbauer-Hohendanner, G, S Mazoua, Catherwood, M, Cayuela, J.M., Ziermann, Janine, F Daraio, S Dulucq, Sacha, T, Chudleigh, Sandra, G Gerrard, Chudleigh, S, G Wilson, Gerrard, Gareth, Farrugia, J, B Milner, M C Müller, P A Merle, Wilkinson, E, L Fletcher, Emons, H., Polakova, K. M., V Hall, Van der Velden, V.HJ., Wren, D., Nickless, G, Pajič, T., Sacha, T., Cross, N C P, Merle, Pa, Pfeifer, Heike, Merle, P.A., Ziermann, J, Touloumenidou, T., Zoi, K., Cross, NCP, Lion, Thomas, Trapmann, S, Wren, D, El Akiki, Susanna, McCarron, S, H Pfeifer, Corbisier, P, Wilkinson, Elizabeth, Pfeifer, H., Jurcek, T, Johnels, P., Boeckx, Nancy, Gerrard, G, N C P Cross, Ziermann, J., Leibundgut, O., Zadro, R., Martinelli, G., Colomer, Dolors, Izzo, B, White, Helen E., Romeo, G., T Pajič, Farrugia, Joanna, H Emons, P Corbisier, A Bench, Lange, T., G Barbany, Foroni, Letizia, Ganderton, Rosalind H., Raudsepp, K., Mitterbauer-Hohendanner, G., J Ziermann, Martinelli, G, Waits, P, Clench, Tim, Ganderton, R, Daraio, F., Zadro, R, H Schimmel, Kim, D-W., Johnels, Petra, Fletcher, Linda, G Nickless, D A Nymoen, Chudleigh, S., Talmaci, R., Mazoua, S, Nymoen, Da, Oppliger Leibundgut, Elisabeth, T Lion, Bench, A., Dulucq, Stéphanie, Clench, T., Nickless, G., Gineikienė, E., L Deprez, E Wilkinson, Zoi, Katerina, Boeckx, N, Nymoen, D.A., Leibundgut, E.O., T Lange, Nymoen, D A, J-M Cayuela, Mueller, M.C., Johnels, P, Barbany-Bustinza, Gisela, Sacha, Tomasz, Jansson, M., Mitterbauer-Hohendanner, Gerlinde Juliane, Lion, T., Müller, Martin Christian, Van der Velden, VHJ, Cayuela, J-M., B Izzo, Kizilors, A, Kim, D.W., Van der Velden, V H J, Van der Velden54, V.H.J., Cayuela, Jean Michel, Ozbek, U., MARTINELLI, GIOVANNI, Andrikovics, Hajnalka, Talmaci, R, Nomdedéu, J., Cross, N. C. P., S Akiki, Preudhomme, Claude, Ozbek, Ugur, Pajič, Tadej, Wang, L (Liang), Van Der Velden, Vincent H. J., Jansson, Mattias, Deprez, Liesbet +316 morecore +1 more sourceNanobody‐Conjugated Theranostic Prodrug Targeting αvβ3 Integrin Enables Precision Cancer Therapy With Real‐Time Imaging
Advanced Healthcare Materials, EarlyView.The image shows a schematic form a nanobody‐conjugated theranostic prodrug (NBD) platform targeting tumor‐associated αvβ3 integrin. The NBD system integrates selective nanobody‐mediated tumor recognition, glutathione‐responsive disulfide cleavage for doxorubicin release, and aza‐BODIPY‐based near‐infrared fluorescence for real‐time imaging.Sanu Karan, Hyunseung Lee, Rema Naskar, Mi Young Cho, Hye Sun Park, Eun Hee Han, Soumyadip Hore, Sun Hee Cho, Truc Ngoc Kim Lam, Taewoong Son, Tae Jung Park, Inkyu Hwang, Jonathan L. Sessler, Kwan Soo Hong +13 morewiley +1 more sourceBlocking the APRIL circuit enhances acute myeloid leukemia cell chemosensitivity
Haematologica, 2008 Resistance to chemotherapy-induced cell death represents a major obstacle in the treatment of acute myeloid leukemia. APRIL (A Proliferation Inducing Ligand) is a member of the tumor necrosis factor superfamily that plays a key role in normal B-cell ...Désirée Bonci, Maria Musumeci, Valeria Coppola, Antonio Addario, Concetta Conticello, Michael Hahne, Massimo Gulisano, Francesco Grignani, Ruggero De Maria +8 moredoaj +1 more sourceFunctional Genomic Landscape of Acute Myeloid Leukemia
Nature, 2018 The implementation of targeted therapies for acute myeloid leukaemia (AML) has been challenging because of the complex mutational patterns within and across patients as well as a dearth of pharmacologic agents for most mutational events.J. Tyner, C. Tognon, D. Bottomly, Beth Wilmot, S. Kurtz, S. Savage, Nicola Long, Anna Reister Schultz, E. Traer, Melissa L. Abel, A. Agarwal, A. Blucher, U. Borate, Jade Bryant, Russell T. Burke, A. Carlos, Richie Carpenter, J. Carroll, B. Chang, Cody Coblentz, Amanda d’Almeida, R. Cook, A. Danilov, K. Dao, Michie Degnin, D. Devine, J. Dibb, David K Edwards, C. Eide, I. English, J. Glover, Rachel Henson, Hibery Ho, Abdusebur Jemal, Kara Johnson, Ryan C. Johnson, Brian Junio, A. Kaempf, Jessica T. Leonard, Chen-Jzong Lin, S. Liu, Pierrette Lo, M. Loriaux, Samuel B. Luty, T. Macey, Jason D. MacManiman, Jacqueline Martinez, M. Mori, D. Nelson, Ceilidh Nichols, Jill Peters, Justin W Ramsdill, Angela Rofelty, R. Schuff, R. Searles, E. Segerdell, Rebecca Smith, S. Spurgeon, Tyler Sweeney, Aashis Thapa, Corinne Visser, Jacob P. Wagner, Kevin Watanabe-Smith, Kristen Werth, Joelle Wolf, Libbey White, Amy Yates, Haijiao Zhang, C. Cogle, R. Collins, D. Connolly, M. Deininger, L. Drusbosky, C. Hourigan, C. Jordan, P. Kropf, Tara L. Lin, M. Martinez, B. Medeiros, Rachel R. Pallapati, D. Pollyea, R. Swords, J. Watts, S. Weir, D. Wiest, R. M. Winters, S. McWeeney, B. Druker +87 moresemanticscholar +1 more sourceDe novo UBE2A mutations are recurrently acquired during chronic myeloid leukemia progression and interfere with myeloid differentiation pathways
Haematologica, 2019 Despite the advent of tyrosine kinase inhibitors, a proportion of chronic myeloid leukemia patients in chronic phase fail to respond to imatinib or to second-generation inhibitors and progress to blast crisis. Until now, improvements in the understanding Vera Magistroni, Mario Mauri, Deborah D’Aliberti, Caterina Mezzatesta, Ilaria Crespiatico, Miriam Nava, Diletta Fontana, Nitesh Sharma, Wendy Parker, Andreas Schreiber, David Yeung, Alessandra Pirola, Sara Readelli, Luca Massimino, Paul Wang, Praveen Khandelwal, Stefania Citterio, Michela Viltadi, Silvia Bombelli, Roberta Rigolio, Roberto Perego, Jacqueline Boultwood, Alessandro Morotti, Giuseppe Saglio, Dong-Wook Kim, Susan Branford, Carlo Gambacorti-Passerini, Rocco Piazza +27 moredoaj +1 more sourceCDK4/6 Inhibition Induces CD8+ T Cell Antitumor Immunity via MIF‐Induced Functional Orchestration of Tumor‐Associated Macrophages
Advanced Science, EarlyView.CDK4/6 inhibition promotes CD8+ T cell expansion through tumor‐macrophage crosstalk by activating HIF‐1α and enhancing MIF‐CD44/CD74 signaling. This reprograms TAMs to boost MHC‐I antigen presentation, and CDK4/6 inhibitor‐trained M1 TAM supernatant therapy synergizes with low‐dose PD‐1 blockade to restore antitumor immunity.Lin He, Yuzhong Peng, Lat‐lun Leong, Jingbo Zhou, Dongyang Tang, Weilu Wang, Xiaoran Wu, Josh haipeng Lei, Yongqin Ye, Yangyang Feng, Yunfeng Qiao, Xiangpeng Chu, Di Mu, Qi Zhao, Tzuming Liu, Yan Chen, Paul Kwonghang Tam, Chu‐Xia Deng +17 morewiley +1 more source
