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Managing plasma cell leukemia

Leukemia & Lymphoma, 2007
Plasma cell leukemia represents a unique subset of patients with multiple myeloma. The definition requires that: (i) for a blood leukocyte count of >10 000/µl, at least 2000/µl are circulating plas...
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Plasma cell dyscrasias and leukemias

Update on Cancer Therapeutics, 2005
Abstract There has been remarkable progress in our understanding of plasma cell dyscrasias and leukemias in recent years. New prognostic factors have come to light. Del(1)(p12) and t(4;14) confer poor prognoses on patients with myeloma. COX-2 positivity is associated with poorer progression-free and overall survival in myeloma patients and a role for
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Plasma Cell Leukemia

2017
Primary plasma cell leukemia (pPCL) is a de novo presentation of an aggressive extramedullary myeloma characterized by circulating plasma cells in peripheral blood. The clonal plasma cells may accumulate genetic aberrations rapidly in a very short period, resulting in de novo pPCL (from monoclonal gammopathy of undetermined significance to pPCL ...
Nisha S. Joseph   +2 more
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[Plasma cell leukemia].

Schweizerische Rundschau fur Medizin Praxis = Revue suisse de medecine Praxis, 1989
The following article describes five patients with plasma cell leukemia treated during the last two years at a Medical University Polyclinic. Plasma cell leukemia is a disease which was seen extremely rarely in the past. The disease can develop in patients with multiple myeloma or, even more rarely, as a "de novo" disease.
F, Egli, K, Rhyner
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[Plasma cell leukemia].

Bulletin du cancer, 2015
Plasma cell leukemia (PCL) is a rare disorder which develops spontaneously (primary PCL) or evolves in patients with multiple myeloma (secondary PCL). It is defined by the presence of 2 × 10(9)/L peripheral blood plasma cells or plasmacytosis accounting for more than 20 % of the differential white cell count.
Aurélie, Ravinet   +2 more
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Plasma Cell Leukemia

2016
Plasma cell leukemia (PCL) is a rare and aggressive form of multiple myeloma (MM). It is characterized by the presence of a large number of circulating clonal plasma cells. It is comprised of two forms: (1) primary PCL (pPCL) which originate de novo with no prior history of MM and (2) secondary PCL (sPCL) where patients with a prior history of MM ...
Wilson I. Gonsalves, Shaji K. Kumar
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Plasma cell leukemia.

Seminars in hematology, 1987
In summary, plasma cell leukemia is a rare disorder that can develop spontaneously or evolve in patients with multiple myeloma. The diagnosis is based on laboratory features, including a plasmacytosis exceeding 2 X 10(9)/L or 20% of the differential cell count.
M A, Kosmo, R P, Gale
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ACUTE PLASMA CELL LEUKEMIA

The American Journal of the Medical Sciences, 1958
L S, RALSTON, W A, WASDAHL, A K, SAIKI
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