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Genomics of Plasma Cell Leukemia. [PDF]
Plasma cell leukemia (PCL) is a rare and highly aggressive plasma cell dyscrasia characterized by the presence of clonal circulating plasma cells in peripheral blood. PCL accounts for approximately 2–4% of all multiple myeloma (MM) cases. PCL can be classified in primary PCL (pPCL) when it appears de novo and in secondary PCL (sPCL) when it arises from
Rojas EA, Gutiérrez NC.
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The potential role of BCL-2 inhibition in amyloidosis and plasma cell leukemia [PDF]
Plasma cell neoplasms include a spectrum of disorders, such as plasma cell leukemia (PCL) and light chain (AL) amyloidosis, all associated with poor prognosis and limited therapeutic options.
Grigorios Alvanidis +4 more
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We present a rare case report of a patient diagnosed with primary plasma cell leukemia (PCL) who presented with atypical signs and symptoms which acutely evolved into life-threatening multi-organ failure.
Shaylika Chauhan +7 more
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Plasma cell leukemia mimicking hairy cell leukemia
A42-year-old female presented with fever and shortness of breath, and was diagnosed with community acquired pneumonia. On presentation she was found to have a white cell count of 13 · 10/L, hemoglobin of 7.1 g/dL and platelets of 51 · 10/L. Peripheral blood smear showed left shift and many cells with hairy projections (56%) (See Fig.
Amr Hanbali +2 more
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Atypical Plasma Cell Leukemia Mistaken for Acute Leukemia: A Case Report [PDF]
The patient we present here had many clinical, morphological, and laboratory findings characteristic of acute leukemia. During the course of the disease, the diagnosis changed from acute leukemia to chronic small B-cell lymphoproliferative disease, a ...
Irena Seili-Bekafigo +6 more
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Plasma cell leukemia (i.e., plasmacytic leukemia) is a very rare and aggressive form of plasma cell dyscrasia characterized by a poor prognosis, short survival time, and a poor response to the administered therapy.
Đurđević Predrag, Jovanović Danijela
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Rapid complete remission after one cycle of isatuximab-based quadruplet regimen in 1q21-positive primary plasma cell leukemia: a case report [PDF]
Primary plasma cell leukemia (pPCL) is a rare and highly aggressive plasma cell malignancy. Patients often present with a large number of circulating plasma cells and extramedullary organ involvement at an early stage of the disease, frequently ...
Lei Pang +8 more
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Abstract A case of plasma cell leukemia is reported, together with a review of the literature, including a summary of the signs, symptoms, and laboratory findings usually present. The relationship of this leukemic state to ordinary plasmacytoma, a tumor of white cell origin, is discussed.
W T, MOSS, L V, ACKERMAN
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