Results 1 to 10 of about 961,470 (198)

Plasma cell leukemia mimicking hairy cell leukemia

open access: yesHematology/Oncology and Stem Cell Therapy, 2015
A42-year-old female presented with fever and shortness of breath, and was diagnosed with community acquired pneumonia. On presentation she was found to have a white cell count of 13 · 10/L, hemoglobin of 7.1 g/dL and platelets of 51 · 10/L. Peripheral blood smear showed left shift and many cells with hairy projections (56%) (See Fig.
Amr Hanbali   +2 more
doaj   +4 more sources

Genomics of Plasma Cell Leukemia

open access: yesCancers, 2022
Plasma cell leukemia (PCL) is a rare and highly aggressive plasma cell dyscrasia characterized by the presence of clonal circulating plasma cells in peripheral blood. PCL accounts for approximately 2–4% of all multiple myeloma (MM) cases. PCL can be classified in primary PCL (pPCL) when it appears de novo and in secondary PCL (sPCL) when it arises from
Elizabeta A. Rojas, Norma C. Gutiérrez
openaire   +4 more sources

Plasma cell leukemia

open access: yesJournal of Family Medicine and Primary Care, 2018
We present a rare case report of a patient diagnosed with primary plasma cell leukemia (PCL) who presented with atypical signs and symptoms which acutely evolved into life-threatening multi-organ failure.
Shaylika Chauhan   +7 more
doaj   +3 more sources

The Cytogenetic Profile of Primary and Secondary Plasma Cell Leukemia: Etiopathogenetic Perspectives, Prognostic Impact and Clinical Relevance to Newly Diagnosed Multiple Myeloma with Differential Circulating Clonal Plasma Cells

open access: yesBiomedicines, 2022
Plasma cell leukemia (PCL) is a rare and aggressive plasma cell dyscrasia that may appear as de-novo leukemia (pPCL) or on the basis of a pre-existing multiple myeloma (MM), called secondary plasma cell leukemia (sPCL). In this prospective study, we have
Stefanos I. Papadhimitriou   +8 more
doaj   +2 more sources

Plasma cell leukemia: A review of the molecular classification, diagnosis, and evidenced-based treatment

open access: yesLeukemia Research, 2021
Plasma cell leukemia is a rare and aggressive plasma cell dyscrasia associated with dismal outcomes. It may arise de novo, primary plasma cell leukemia, or evolve from an antecedent diagnosis of multiple myeloma, secondary plasma cell leukemia.
Krisstina Gowin   +2 more
exaly   +2 more sources

Plasma cell leukemia [PDF]

open access: yesSrpski Medicinski Časopis Lekarske Komore
Plasma cell leukemia (i.e., plasmacytic leukemia) is a very rare and aggressive form of plasma cell dyscrasia characterized by a poor prognosis, short survival time, and a poor response to the administered therapy.
Đurđević Predrag, Jovanović Danijela
doaj   +2 more sources

Rapid complete remission after one cycle of isatuximab-based quadruplet regimen in 1q21-positive primary plasma cell leukemia: a case report [PDF]

open access: yesFrontiers in Immunology
Primary plasma cell leukemia (pPCL) is a rare and highly aggressive plasma cell malignancy. Patients often present with a large number of circulating plasma cells and extramedullary organ involvement at an early stage of the disease, frequently ...
Lei Pang   +8 more
doaj   +2 more sources

Plasma Cell Leukemia: Definition, Presentation, and Treatment

open access: yesCurrent Oncology Reports, 2019
Purpose of ReviewWe discuss current topics on the definition of plasma cell leukemia and the distinction between plasma cell leukemia and multiple myeloma.
Niels Abildgaard   +2 more
exaly   +2 more sources

Prognostic impact of circulating plasma cells in patients with multiple myeloma: implications for plasma cell leukemia definition

open access: yesHaematologica, 2017
The presence of circulating plasma cells in patients with multiple myeloma is considered a marker for highly proliferative disease. In the study herein, the impact of circulating plasma cells assessed by cytology on survival of patients with multiple ...
Miquel Granell   +16 more
doaj   +2 more sources

Flaming Plasma Cell Leukemia

open access: yesTurkish Journal of Hematology, 2018
Reza Ranjbaran, Habibollah Golafshan
doaj   +3 more sources

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