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Plasma cell leukemia mimicking hairy cell leukemia
A42-year-old female presented with fever and shortness of breath, and was diagnosed with community acquired pneumonia. On presentation she was found to have a white cell count of 13 · 10/L, hemoglobin of 7.1 g/dL and platelets of 51 · 10/L. Peripheral blood smear showed left shift and many cells with hairy projections (56%) (See Fig.
Amr Hanbali +2 more
doaj +4 more sources
Genomics of Plasma Cell Leukemia
Plasma cell leukemia (PCL) is a rare and highly aggressive plasma cell dyscrasia characterized by the presence of clonal circulating plasma cells in peripheral blood. PCL accounts for approximately 2–4% of all multiple myeloma (MM) cases. PCL can be classified in primary PCL (pPCL) when it appears de novo and in secondary PCL (sPCL) when it arises from
Elizabeta A. Rojas, Norma C. Gutiérrez
openaire +4 more sources
We present a rare case report of a patient diagnosed with primary plasma cell leukemia (PCL) who presented with atypical signs and symptoms which acutely evolved into life-threatening multi-organ failure.
Shaylika Chauhan +7 more
doaj +3 more sources
Plasma cell leukemia (PCL) is a rare and aggressive plasma cell dyscrasia that may appear as de-novo leukemia (pPCL) or on the basis of a pre-existing multiple myeloma (MM), called secondary plasma cell leukemia (sPCL). In this prospective study, we have
Stefanos I. Papadhimitriou +8 more
doaj +2 more sources
Plasma cell leukemia is a rare and aggressive plasma cell dyscrasia associated with dismal outcomes. It may arise de novo, primary plasma cell leukemia, or evolve from an antecedent diagnosis of multiple myeloma, secondary plasma cell leukemia.
Krisstina Gowin +2 more
exaly +2 more sources
Plasma cell leukemia (i.e., plasmacytic leukemia) is a very rare and aggressive form of plasma cell dyscrasia characterized by a poor prognosis, short survival time, and a poor response to the administered therapy.
Đurđević Predrag, Jovanović Danijela
doaj +2 more sources
Rapid complete remission after one cycle of isatuximab-based quadruplet regimen in 1q21-positive primary plasma cell leukemia: a case report [PDF]
Primary plasma cell leukemia (pPCL) is a rare and highly aggressive plasma cell malignancy. Patients often present with a large number of circulating plasma cells and extramedullary organ involvement at an early stage of the disease, frequently ...
Lei Pang +8 more
doaj +2 more sources
Plasma Cell Leukemia: Definition, Presentation, and Treatment
Purpose of ReviewWe discuss current topics on the definition of plasma cell leukemia and the distinction between plasma cell leukemia and multiple myeloma.
Niels Abildgaard +2 more
exaly +2 more sources
The presence of circulating plasma cells in patients with multiple myeloma is considered a marker for highly proliferative disease. In the study herein, the impact of circulating plasma cells assessed by cytology on survival of patients with multiple ...
Miquel Granell +16 more
doaj +2 more sources

