Results 21 to 30 of about 961,470 (198)

Single cell transcriptomic analysis reveals BCMA CAR-T cell dynamics in a patient with refractory primary plasma cell leukemia.

open access: yesMolecular Therapy, 2020
Chimeric antigen receptor T-cell(CAR-T)therapy has revolutionized the clinical treatment of hematological malignancies due to the prominent anti-tumor effects.
Xue Li   +22 more
semanticscholar   +1 more source

Pleomorphic plasma cell leukemia [PDF]

open access: yesBlood, 2015
![Figure][1] This peripheral blood smear is from a 72-year-old woman, taken several hours before she died of recurrent plasma cell myeloma and newly developed secondary plasma cell leukemia.
Huifei, Liu, Xiaoping, Sun
openaire   +2 more sources

Plasma cell leukemia: Clinicopathologic, immunophenotypic and cytogenetic characteristics of 4 cases

open access: yesHematology/Oncology and Stem Cell Therapy, 2015
Plasma cell leukemia (PCL) is a rare hematologic malignancy with very poor outcome. It is defined by the presence of >2 × 109/L plasma cells or >20%s plasmacytosis of the differential white cell count in the peripheral blood.
Nahlah Alghasham   +3 more
doaj   +1 more source

Clinical and cytogenetic characteristics of primary and secondary plasma cell leukemia under the new IMWG definition criteria: a retrospective study

open access: yesHematology, 2023
Background Plasma cell leukemia (PCL) is a rare and aggressive plasma cell disorder, exhibiting a more unfavorable prognosis than multiple myeloma. PCL is classified into pPCL and sPCL.
Jiaheng Guan, Jinlong Ma, Baoan Chen
doaj   +1 more source

Primary plasma cell leukemia and autologous stem cell transplantation

open access: yesHaematologica, 2010
Background Primary plasma cell leukemia is a rare disorder accounting for less than 5% of malignant plasma cell diseases. It has a poor prognosis compared to multiple myeloma, with a median survival of 8–12 months. The results of conventional therapy are
Mary B. Drake   +7 more
doaj   +1 more source

Hairy Cell Leukemia with Marrow Reactive Plasmacytosis and Mast Cell Hyperplasia: A Case Report and Brief Review of the Literature [PDF]

open access: yesJournal of Kerman University of Medical Sciences, 2023
Hairy cell leukemia (HCL) and HCL-like disorders, including HCL-variant, are disorders of heterogeneous mature lymphoid B-cells known for their hairy cell infiltration accompanied by a specific genetic profile, various clinical presentations, and, as ...
Elham Jafari   +2 more
doaj   +1 more source

B-lymphoblastic leukemia/lymphoma arising in treated plasma cell myeloma: A rare second malignancy

open access: yesHuman Pathology: Case Reports, 2017
Plasma cell myeloma (PCM) is a neoplasm of plasma cells, end-stage post germinal center B cells, which shows a variable clinical spectrum from asymptomatic to aggressive; the nature of the disease is generally progressive. Rarely, leukemia arises treated
D. Kurant   +3 more
doaj   +1 more source

Plasma cell leukemia: A case series from South India with emphasis on rarer variants

open access: yesIndian Journal of Medical and Paediatric Oncology, 2014
Plasma cell leukemia (PCL) is a rare and aggressive variant of plasma cell dyscrasia. They occur de novo (primary) or as a late manifestation of multiple myeloma (secondary). Patients present with anemia, thrombocytopenia, renal failure, organomegaly and
G Rajeswari   +6 more
doaj   +1 more source

Case Report: Concomitant Diagnosis of Plasma Cell Leukemia in Patient With JAK2 Positive Myeloproliferative Neoplasm

open access: yesFrontiers in Oncology, 2020
Plasma cell dyscrasias and myeloproliferative neoplasms (MPN) are hematologic malignancies arising from two distinct hematopoietic cell lineages. They rarely occur concomitantly. Here, we report a case of a patient with a recent diagnosis of a JAK2 V617F
Christine J. Kurian   +4 more
doaj   +1 more source

Hairy-plasma cell leukemia

open access: yesJournal of Applied Hematology, 2015
Plasma cell leukemia (PCL) is defined by the presence of more than 2 × 109/L PCs in the peripheral blood. It is a very rare type of leukemia with poor outcome. In this case, we report a PCL case with peripheral blood morphology of hairy cell leukemia. We
Nahlah Alghasham   +3 more
doaj   +1 more source

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