Results 31 to 40 of about 961,470 (198)

Rare case of plasma cell myeloma with megakaryoblastic morphology mimicking acute leukemia

Indian Journal of Pathology and Microbiology, 2020
Myeloma plasma cells vary from mature forms to immature, plasmablastic, and pleomorphic cells. Only a few cases of morphologic variant of plasma cell neoplasm have been reported, in which the plasma cell neoplasm presented with lymphoplasmacytic ...
Keyu Liu, Huijuan Song, Jie Shi, Weijun Zhang, Rui Mu, Li Li   +5 more
doaj   +1 more source

IgA Plasma Cell Leukemia

Journal of Laboratory Physicians, 2009
ABSTRACTPlasma cell leukemia (PCL) is a rare entity. There are two presentations of PCL, primary or secondary. The primary or de novo form of PCL presents with an acute and rapidly progressive leukemic phase. This form occurs when the patient has no pre-existing multiple myeloma (MM). The secondary form is the most advanced form of MM.
Singh, Tejinder, Premalata, CS, Sajeevan, KV, Jain, Ankit, Batra, Ullas, Saini, KS, Satheesh, CT, Babu, K Govind, Lokanatha, D   +8 more
openaire   +2 more sources

Immunophenotypic profile of plasma cell leukemia: A retrospective study in a reference cancer center in India and review of literature

Indian Journal of Pathology and Microbiology, 2011
Background: Plasma cell leukemia (PCL) is a rare but aggressive subtype of plasma cell dyscrasia. It is known to present with highly variable morphological features and may mimic with other lymphoid neoplasms.
Prashant R Tembhare, P G Subramanian, Kunal Sehgal, Badrinath Yajamanam, Ashok Kumar, Vijaya Gadge, Nitin Inamdar, Sumeet Gujral   +7 more
doaj   +1 more source

A Rare Case of Renal Thrombotic Microangiopathy and Focal Segmental Glomerulosclerosis Secondary to Plasma Cell Leukemia

Case Reports in Hematology, 2023
Plasma cell dyscrasias are a subset of hematological malignancies involving the production of monoclonal immunoglobulins. This spectrum of disorders includes asymptomatic conditions such as monoclonal gammopathy of unknown significance as well as ...
Justin Komisarof, Jessica Forman, Bruce Goldman, Chauncey Syposs, Frank Passero, Ellie Garbade   +5 more
doaj   +1 more source

Revised diagnostic criteria for plasma cell leukemia: results of a Mayo Clinic study with comparison of outcomes to multiple myeloma

Blood Cancer Journal, 2018
The current definition of plasma cell leukemia (PCL)— ≥ 20% circulating plasma cells (CPCs) on peripheral smear and plasma cell count ≥ 2 × 109/L—may be too stringent.
P. Ravi, Shaji K. Kumar, Lindsey E. Roeker, W. Gonsalves, F. Buadi, M. Lacy, R. Go, A. Dispenzieri, P. Kapoor, J. Lust, D. Dingli, Yi Lin, S. Russell, N. Leung, M. Gertz, R. Kyle, P. Bergsagel, S. Rajkumar   +17 more
semanticscholar   +1 more source

Successful treatment with bortezomib-containing regimen of primary plasma cell leukemia: a case report

The Pan African Medical Journal, 2020
Plasma cell leukemia represents the most aggressive form of plasma cell dyscrasia.We report a 67-year old male with no previous medical illnesses presented with anemic symptoms.
Mohammad Bader Obeidat, Ali Mohammad Al-Swailmeen, Abdulmajeed Mohammad Arabeat, Ayman Sulaiman Abukamar   +3 more
doaj   +1 more source

Plasma Cell Leukemia with Myelofibrosis

Journal of Clinical and Experimental Hematopathology, 2008
Myelofibrosis, which is usually observed as one of the primary forms of chronic myeloproliferative disorders, is characterized by splenomegaly and fibrotic bone marrow. The disease is observed in 10 to 30% patients with multiple myeloma. The degree of the marrow fibrosis tends to correlate with the magnitude of plasma cell infiltration and therefore ...
Kasahara, Senji, Tsurumi, Hisashi, Yoshikawa, Takeshi, Hara, Takeshi, Shimizu, Masahito, Oyama, Masami, Moriwaki, Hisataka   +6 more
openaire   +3 more sources

The combination of venetoclax, daratumumab and dexamethasone for the treatment of refractory primary plasma cell leukemia

American journal of hematology/oncology, 2019
The combination of venetoclax, daratumumab and dexamethasone for the treatment of refractory primary plasma cell leukemia To the Editor: Primary plasma cell leukemia (pPCL) is a rare and aggressive form of multiple myeloma (MM) characterized by the ...
Sos Nalghranyan, Amrit P. Singh, C. Schinke   +2 more
semanticscholar   +1 more source

Atypical Plasma Cell Leukemia Mistaken for Acute Leukemia: A Case Report

Medicina
The patient we present here had many clinical, morphological, and laboratory findings characteristic of acute leukemia. During the course of the disease, the diagnosis changed from acute leukemia to chronic small B-cell lymphoproliferative disease, a ...
Irena Seili-Bekafigo, Emina Torlakovic, Tajana Grenko Malnar, Marija Stanić Damić, Željko Prka, Koviljka Matušan Ilijaš, Ita Hadžisejdić   +6 more
doaj   +1 more source

Plasma Cell Leukemia: A Review of 3 Cases Managed in Kenya

Case Reports in Hematology, 2021
Plasma Cell Leukemia (PCL) is a rare and aggressive form of plasma cell dyscrasia that can arise either de novo (primary plasma cell leukemia) or evolve from previously diagnosed and treated multiple myeloma (secondary PCL).
Matilda Ong’ondi, Elizabeth Kagotho
doaj   +1 more source