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Plasma cell leukemia (PCL) is a rare, yet aggressive plasma cell (PC) neoplasm, variant of multiple myeloma (MM), characterized by high levels of PCs circulating in the peripheral blood. PCL can either originate de novo (primary PCL) or as a secondary leukemic transformation of MM (secondary PCL). Presenting signs and symptoms are similar to those seen
Flavio, Albarracin, Rafael, Fonseca
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Pleomorphic plasma cell leukemia [PDF]
![Figure][1] This peripheral blood smear is from a 72-year-old woman, taken several hours before she died of recurrent plasma cell myeloma and newly developed secondary plasma cell leukemia.
Huifei, Liu, Xiaoping, Sun
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Plasma cell leukemia: Clinicopathologic, immunophenotypic and cytogenetic characteristics of 4 cases
Plasma cell leukemia (PCL) is a rare hematologic malignancy with very poor outcome. It is defined by the presence of >2 × 109/L plasma cells or >20%s plasmacytosis of the differential white cell count in the peripheral blood.
Nahlah Alghasham +3 more
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Background Plasma cell leukemia (PCL) is a rare and aggressive plasma cell disorder, exhibiting a more unfavorable prognosis than multiple myeloma. PCL is classified into pPCL and sPCL.
Jiaheng Guan, Jinlong Ma, Baoan Chen
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Primary plasma cell leukemia and autologous stem cell transplantation
Background Primary plasma cell leukemia is a rare disorder accounting for less than 5% of malignant plasma cell diseases. It has a poor prognosis compared to multiple myeloma, with a median survival of 8–12 months. The results of conventional therapy are
Mary B. Drake +7 more
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Hairy Cell Leukemia with Marrow Reactive Plasmacytosis and Mast Cell Hyperplasia: A Case Report and Brief Review of the Literature [PDF]
Hairy cell leukemia (HCL) and HCL-like disorders, including HCL-variant, are disorders of heterogeneous mature lymphoid B-cells known for their hairy cell infiltration accompanied by a specific genetic profile, various clinical presentations, and, as ...
Elham Jafari +2 more
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B-lymphoblastic leukemia/lymphoma arising in treated plasma cell myeloma: A rare second malignancy
Plasma cell myeloma (PCM) is a neoplasm of plasma cells, end-stage post germinal center B cells, which shows a variable clinical spectrum from asymptomatic to aggressive; the nature of the disease is generally progressive. Rarely, leukemia arises treated
D. Kurant +3 more
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Venetoclax in the treatment of secondary plasma cell leukemia with translocation t(11;14): a case report and literature review. [PDF]
Elsabah H +5 more
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Plasma cell leukemia: A case series from South India with emphasis on rarer variants
Plasma cell leukemia (PCL) is a rare and aggressive variant of plasma cell dyscrasia. They occur de novo (primary) or as a late manifestation of multiple myeloma (secondary). Patients present with anemia, thrombocytopenia, renal failure, organomegaly and
G Rajeswari +6 more
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