Results 11 to 20 of about 1,245,695 (368)

European LeukemiaNet 2020 recommendations for treating chronic myeloid leukemia

open access: yesLeukemia, 2020
The therapeutic landscape of chronic myeloid leukemia (CML) has profoundly changed over the past 7 years. Most patients with chronic phase (CP) now have a normal life expectancy.
A. Hochhaus   +33 more
semanticscholar   +1 more source

Epidemiology of leukemia and multiple myeloma in golestan, Iran [PDF]

open access: yes, 2013
Background: The aim of this paper was to present the incidence rates of leukemia and multiple myeloma (MM) in Golestan province located in northeastern Iran during 2004-2009. Materials and Methods: This was a descriptive cross-sectional study.
Jahangirrad, A.   +5 more
core   +1 more source

Rapid and label-free identification of single leukemia cells from blood in a high-density microfluidic trapping array by fluorescence lifetime imaging microscopy. [PDF]

open access: yes, 2018
The rapid screening and isolation of single leukemia cells from blood has become critical for early leukemia detection and tumor heterogeneity interrogation. However, due to the size overlap between leukemia cells and the more abundant white blood cells (
Digman, Michelle A   +4 more
core   +1 more source

Tisagenlecleucel in Children and Young Adults with B‐Cell Lymphoblastic Leukemia

open access: yesNew England Journal of Medicine, 2018
Background In a single‐center phase 1–2a study, the anti‐CD19 chimeric antigen receptor (CAR) T‐cell therapy tisagenlecleucel produced high rates of complete remission and was associated with serious but mainly reversible toxic effects in children and ...
S. Maude   +34 more
semanticscholar   +1 more source

Information-theoretic multi-time-scale partially observable systems with inspiration from leukemia treatment [PDF]

open access: yes, 2022
We study a partially observable nonlinear stochastic system with unknown parameters, where the given time scales of the states and measurements may be distinct. The proposed setting is inspired by disease management, particularly leukemia.
arxiv   +1 more source

Kernel Logistic Regression-linear for Leukemia Classification Using High Dimensional Data [PDF]

open access: yes, 2009
Kernel Logistic Regression (KLR) is one of the statistical models that has been proposed for classification in the machine learning and data mining communities, and also one of the effective methodologies in the kernel–machine techniques.
Embong, A. (A)   +3 more
core   +3 more sources

Chimeric antigen receptor T cells for sustained remissions in leukemia.

open access: yesNew England Journal of Medicine, 2014
BACKGROUND Relapsed acute lymphoblastic leukemia (ALL) is difficult to treat despite the availability of aggressive therapies. Chimeric antigen receptor-modified T cells targeting CD19 may overcome many limitations of conventional therapies and induce ...
S. Maude   +18 more
semanticscholar   +1 more source

Leukemia and rosiglitazone

open access: yesSaudi Pharmaceutical Journal, 2016
The article titled “Can an oral antidiabetic (rosiglitazone) be of benefit in leukemia treatment?” written by Cetinkalp et al. and published in one of the recent issues of your journal was quite interesting (Cetinkalp et al., 2015). Here, we would like to emphasize some points. Pan et al.
Irfan Yavasoglu   +2 more
openaire   +4 more sources

CREB is a critical regulator of normal hematopoiesis and leukemogenesis [PDF]

open access: yes, 2008
The cAMP-responsive element binding protein (CREB) is a 43-kDa nuclear transcription factor that regulates cell growth, memory, and glucose homeostasis. We showed previously that CREB is amplified in myeloid leukemia blasts and expressed at higher levels
Akashi   +55 more
core   +3 more sources

Genomic Classification and Prognosis in Acute Myeloid Leukemia.

open access: yesNew England Journal of Medicine, 2016
BACKGROUND Recent studies have provided a detailed census of genes that are mutated in acute myeloid leukemia (AML). Our next challenge is to understand how this genetic diversity defines the pathophysiology of AML and informs clinical practice ...
E. Papaemmanuil   +26 more
semanticscholar   +1 more source

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