European LeukemiaNet 2020 recommendations for treating chronic myeloid leukemia
Leukemia, 2020 The therapeutic landscape of chronic myeloid leukemia (CML) has profoundly changed over the past 7 years. Most patients with chronic phase (CP) now have a normal life expectancy.
A. Hochhaus +33 more
semanticscholar +1 more source
Epidemiology of leukemia and multiple myeloma in golestan, Iran [PDF]
, 2013 Background: The aim of this paper was to present the incidence rates of leukemia and multiple myeloma (MM) in Golestan province located in northeastern Iran during 2004-2009. Materials and Methods: This was a descriptive cross-sectional study.
Jahangirrad, A. +5 more
core +1 more source
Rapid and label-free identification of single leukemia cells from blood in a high-density microfluidic trapping array by fluorescence lifetime imaging microscopy. [PDF]
, 2018 The rapid screening and isolation of single leukemia cells from blood has become critical for early leukemia detection and tumor heterogeneity interrogation. However, due to the size overlap between leukemia cells and the more abundant white blood cells (
Digman, Michelle A +4 more
core +1 more source
Tisagenlecleucel in Children and Young Adults with B‐Cell Lymphoblastic Leukemia
New England Journal of Medicine, 2018 Background In a single‐center phase 1–2a study, the anti‐CD19 chimeric antigen receptor (CAR) T‐cell therapy tisagenlecleucel produced high rates of complete remission and was associated with serious but mainly reversible toxic effects in children and ...
S. Maude +34 more
semanticscholar +1 more source
Information-theoretic multi-time-scale partially observable systems with inspiration from leukemia treatment [PDF]
, 2022 We study a partially observable nonlinear stochastic system with unknown parameters, where the given time scales of the states and measurements may be distinct. The proposed setting is inspired by disease management, particularly leukemia.
arxiv +1 more source
Kernel Logistic Regression-linear for Leukemia Classification Using High Dimensional Data [PDF]
, 2009 Kernel Logistic Regression (KLR) is one of the statistical models that has been proposed for classification in the machine learning and data mining communities, and also one of the effective methodologies in the kernel–machine techniques.
Embong, A. (A) +3 more
core +3 more sources
Chimeric antigen receptor T cells for sustained remissions in leukemia.
New England Journal of Medicine, 2014 BACKGROUND Relapsed acute lymphoblastic leukemia (ALL) is difficult to treat despite the availability of aggressive therapies. Chimeric antigen receptor-modified T cells targeting CD19 may overcome many limitations of conventional therapies and induce ...
S. Maude +18 more
semanticscholar +1 more source
Saudi Pharmaceutical Journal, 2016 The article titled “Can an oral antidiabetic (rosiglitazone) be of benefit in leukemia treatment?” written by Cetinkalp et al. and published in one of the recent issues of your journal was quite interesting (Cetinkalp et al., 2015). Here, we would like to emphasize some points. Pan et al.
Irfan Yavasoglu +2 more
openaire +4 more sources
CREB is a critical regulator of normal hematopoiesis and leukemogenesis [PDF]
, 2008 The cAMP-responsive element binding protein (CREB) is a 43-kDa nuclear transcription factor that regulates cell growth, memory, and glucose homeostasis. We showed previously that CREB is amplified in myeloid leukemia blasts and expressed at higher levels
Akashi +55 more
core +3 more sources
Genomic Classification and Prognosis in Acute Myeloid Leukemia.
New England Journal of Medicine, 2016 BACKGROUND Recent studies have provided a detailed census of genes that are mutated in acute myeloid leukemia (AML). Our next challenge is to understand how this genetic diversity defines the pathophysiology of AML and informs clinical practice ...
E. Papaemmanuil +26 more
semanticscholar +1 more source