Results 241 to 250 of about 809,322 (319)

Single‐Cell Mitochondrial Lineage Tracing Decodes Fate Decision and Spatial Clonal Architecture in Human Hematopoietic Organoids

Advanced Science, EarlyView.
This study repurposes mitochondrial DNA mutations as endogenous barcodes for lineage tracing in human pluripotent stem cell‐derived organoids. Integrated with transcriptomic and spatial data, it reveals NOTCH‐mediated stromal‐progenitor crosstalk orchestrates clonal dynamics and spatial zonation during early hematopoietic development, offering a non ...
Yan Xue, Junhao Su, Yiming Chao, Lu Liu, Xinyi Lin, Yang Xiang, Mun Kay Ho, Zezhuo Su, Junyi Chen, Zhuojuan Luo, Chengqi Lin, Ruibang Luo, Theo Aurich, Jianfeng Wu, Kelvin Sin Chi Cheung, Yuanhua Huang, Joshua W. K. Ho, Ryohichi Sugimura   +17 more
wiley   +1 more source

Structural birth defects and leukemia risk in children with Down syndrome. [PDF]

Sci Rep
Hsu CJ, Schraw JM, Rasmussen SA, Chambers TM, Desrosiers TA, Huff CD, Janitz AE, Kirby RS, Nestoridi E, Nembhard WN, Salemi JL, Shumate C, Tanner JP, Yazdy MM, Scheurer ME, Rabin KR, Lupo PJ.   +16 more
europepmc   +1 more source

Dynamic Decoration of DNA Scaffolds for High‐Resolution Cancer Cell Subtyping

Advanced Science, EarlyView.
This study presents a dual‐mode imaging platform that utilizes self‐assembly and disassembly of DNA scaffolds for high‐resolution cancer cell detection. The structural rigidity of DNA scaffolds effectively prevents cellular internalization for over 300 min.
Xiaolin Hu, Jie Xie, Xinlin Guo, Liangting Wang, Zhengheng Yu, Xiaopei Qiu, Heng Li, Kang Wang, Xiaoxing Wang, Mingxuan Song, Junsong Guo, Wei Gu, Sergio Bernardini, Chaoyong Yang, Hong Zhang, Yang Luo   +15 more
wiley   +1 more source

Proximally biased V(D)J recombination in the clonal evolution of IGH alleles in KMT2A::AFF1 BCP‐ALL of all age classes

HemaSphere
Heiko Müller, Frank Dicker, Constance Bär, Wencke Walter, Stephan Hutter, Niroshan Nadarajah, Manja Meggendorfer, Qingsong Gao, Ilaria Iacobucci, Charles G. Mullighan, Wolfgang Kern, Torsten Haferlach, Claudia Haferlach   +12 more
doaj   +1 more source

A case report and a literature review of Myeloid/Lymphoid Neoplasm with Eosinophilia and PCM1::JAK2 rearrangement representing as B-cell acute lymphoblastic leukemia B-ALL. [PDF]

Ann Hematol
Čemažar L, Šlajpah K, Gredelj Šimec N, Podgornik H.   +3 more
europepmc   +1 more source

The use of venetoclax in the treatment of acute lymphoblastic leukemia-a systematic review. [PDF]

Ther Adv Med Oncol
Kowalczyk A, Zarychta J, Zawitkowska J, Lejman M.   +3 more
europepmc   +1 more source

Dynamic kernel generation through hybrid involution and convolution neural networks for leukemia and white blood cell classification. [PDF]

Sci Rep
Alshehri OM, Shaf A, Shakeel U, Ali T, Irfan M, Jalal MM, Altayar MA, Abu-Alghayth MH, Shmrany HA.   +8 more
europepmc   +1 more source

Leukemia Incidence and Demographic Trends in Saudi Arabia, 1997-2022: A Nationwide Registry Analysis. [PDF]

J Epidemiol Glob Health
Almasmoum HA, Salaka AS, Alamri IY, Halabi WS, Bokhari MM, Hafiz MN, Mujalli A.   +6 more
europepmc   +1 more source