Results 241 to 250 of about 1,742,061 (410)

HERV‐K TM Subunit Elicits CD8+ T Cell Anergy and Tumor Immune Evasion via Targeting CD3 Coreceptor ε in AML and PDAC

Advanced Science, EarlyView.
Novel viral immune checkpoint K‐TM subunit is aberrantly expressed in CD8+ T cells and enriched in sera of cancer patients, inducing CD8+ T cell anergy and eliciting potent tumor immune escape in mouse model. Mechanistically, K‐TM directly targets and induces the phosphorylation of CD3ε receptor.
Mengyuan Li, Shuwen Zheng, Qinyuan Gong, Zhaoxing Wu, Wen Lei, Wanyue Cao, Ping Wang, Xuzhao Zhang, Wenbin Qian, Yun Liang, Ying Lu, Fenglin Li, Qi Zhang, Rongzhen Xu   +13 more
wiley   +1 more source

Aleukemic Stem Cell Leukemia with Polyserositis [PDF]

, 1955
Arthur H. Raynolds, Renzo G. Olivetti, RICHARD W. EKSTRAND   +2 more
openalex   +1 more source

The burden dynamics of leukemia in China from 1990 to 2021: an epidemiological analysis of trends, risk factors, and projections to 2036. [PDF]

Prev Med Rep
Zhang R, Guo C, Liang Y, Qing S, Liang Z, Wang Y, Zhang C.   +6 more
europepmc   +1 more source

Carrier‐Free Nanocapsule with Dual‐Target Capacity for Synergistically Restoring Inflammatory Microenvironment and Microbiota Dysbiosis in Colitis

Advanced Science, EarlyView.
This manuscript presents a carrier‐free nanomedicine PCNPs@PEG‐Man with dual‐targeting for IBD. It resists harsh intestinal conditions, reduces oxidative stress, enhances drug uptake and retention, modulates inflammation, and reshapes gut microbiota, offering a safe and effective IBD therapy.
Yingjie Chen, Yuhan Gao, Kaiyuan Huo, Zhaofan Jin, Wenchao Wang, Xingjie Zan, Yanlong Liu, Limeng Zhu, Jianfeng Yang   +8 more
wiley   +1 more source

Panels in Therapy. VI. The Management of Chronic Lymphocytic Leukemia [PDF]

, 1955
Frank H. Bethell, Lloyd F. Craver, David A. Karnofsky, Edwin E. Osgood   +3 more
openalex   +1 more source

Ibrutinib as Initial Therapy for Patients with Chronic Lymphocytic Leukemia.

New England Journal of Medicine, 2015
J. Burger, A. Tedeschi, P. Barr, T. Robak, C. Owen, P. Ghia, O. Bairey, P. Hillmen, N. Bartlett, Jianyong Li, D. Simpson, S. Grosicki, S. Devereux, H. McCarthy, S. Coutre, H. Quach, G. Gaidano, Z. Maslyak, D. Stevens, A. Janssens, F. Offner, J. Mayer, M. O'Dwyer, A. Hellmann, A. Schuh, T. Siddiqi, A. Polliack, C. Tam, Deepali Suri, M. Cheng, F. Clow, L. Styles, D. James, T. Kipps   +33 more
semanticscholar   +1 more source

Comparative study of liposomal amphotericin B, posaconazole, and micafungin for primary antifungal prophylaxis in pediatric patients with acute leukemia. [PDF]

J Cancer Res Clin Oncol
Gottschlich AS, Ernst J, Milde T, Gruhn B.   +3 more
europepmc   +1 more source

Gastrula‐Premarked Posterior Enhancer Primes Posterior Tissue Development Through Cross‐Talk with TGF‐β Signaling Pathway

Advanced Science, EarlyView.
A gastrula‐premarked enhancer within the first intron of Cdx2 governs posterior embryonic development via both regulating Cdx2 expression in cis and coordinating TGF‐β signaling in trans to ensure proper posterior body development. Functional rescue in gastruloids reveals a Cdx2‐independent pathway, highlighting p‐Enh‐eRNA as key epigenetic ...
Yingying Chen, Fengxiang Tan, Qing Fang, Lin Zhang, Jiaoyang Liao, Penglei Shen, Yun Qian, Mingzhu Wen, Rui Song, Yonggao Fu, He Jax Xu, Ran Wang, Cheng Li, Zhen Shao, Jinsong Li, Naihe Jing, Xianfa Yang   +16 more
wiley   +1 more source

Effect of myleran treatment on the P32 uptake of leukocytic deoxyribonucleic acid in chronic granulocytic leukemia [PDF]

, 1956
Jonah G. Li, M. E. Leonard, G Harrison
openalex   +1 more source

Targeting BTK with ibrutinib in relapsed chronic lymphocytic leukemia.

New England Journal of Medicine, 2013
J. Byrd, R. Furman, S. Coutre, I. Flinn, J. Burger, K. Blum, B. Grant, J. Sharman, M. Coleman, W. Wierda, Jeffrey A Jones, Weiqiang Zhao, N. Heerema, A. Johnson, J. Sukbuntherng, B. Chang, F. Clow, E. Hedrick, J. Buggy, D. James, S. O'brien   +20 more
semanticscholar   +1 more source