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Leukemia inhibitory factor (LIF) is immunohistochemically localized in tubal ectopic pregnancy
Acta Histochemica, 2008 Leukemia inhibitory factor (LIF) is essential for implantation of the embryo in the endometrium. It is not clear whether the blastocyst requires expression of LIF for implantation into tissues other than endometrium. Immunohistochemical localization of LIF was performed in the fallopian tube of 20 women with ectopic pregnancies, 7 women with normal ...
Mehmet Güney +2 more
exaly +7 more sources
Differential hormonal regulation of leukemia inhibitory factor (LIF) in rabbit and mouse uterus
Molecular Reproduction and Development, 1996 Leukemia inhibitory factor (LIF) has been shown to be essential for the implantation of mouse blastocysts. The present study was designed to determine how LIF protein was hormonally regulated in rabbit and mouse uterus using immunohistochemistry. In unmated rabbits, LIF protein was at a low level in the uterine epithelium and glands, and up-regulated ...
Zeng-Ming Yang +2 more
exaly +4 more sources
Neuronal expression of leukemia inhibitory factor (LIF) in the rat brain
Neuroscience Letters, 1996 Very little is known about the action of the leukemia inhibitory factor (LIF) in the central nervous system. To analyze LIF expression in adult rat brain, we used non-radioactive in situ hybridization with digoxigenin-labeled RNA probes, in combination with immunohistochemistry to identify the cell types expressing LIF mRNA. Hippocampal pyramidal cells,
Lemke, R. +4 more
core +5 more sources
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Immobilization of leukemia inhibitory factor (LIF) to culture murine embryonic stem cells
Journal of Bioscience and Bioengineering, 2004Murine embryonic stem (ES) cells were cultured on a material containing immobilized leukemia inhibitory factor (LIF). To immobilize LIF, we synthesized photoreactive gelatin mixed with LIF and cast the mixture on a polystyrene plate, which was then dried. LIF was immobilized by photoirradiation in the presence or absence of a photo mask.
Yoshihiro Ito, Hirokazu Hasuda
exaly +3 more sources
Leukemia inhibitory factor (LIF): A growth factor with pleiotropic effects on bone biology
Progress in Growth Factor Research, 1992Historically, growth factors are denominated based on a specific biological activity. In many cases, these factors display a much broader spectrum of activities, especially when their effect is tested on various cell or tissue types. Consequently, names of certain factors are quite deceptive. A textbook example is leukemia inhibitory factor (LIF).
exaly +3 more sources
Molecular and Cellular Endocrinology, 2000
It is well established that steroidogenesis in the adrenal cortex is regulated by extraadrenal factors, such as ACTH and angiotensin II. However, over the last years, it has become increasingly clear that paracrine and autocrine mechanisms are also important for steroid synthesis in the adrenal gland.
Roman Jung +2 more
exaly +3 more sources
It is well established that steroidogenesis in the adrenal cortex is regulated by extraadrenal factors, such as ACTH and angiotensin II. However, over the last years, it has become increasingly clear that paracrine and autocrine mechanisms are also important for steroid synthesis in the adrenal gland.
Roman Jung +2 more
exaly +3 more sources
A role for Leukemia Inhibitory Factor (LIF) during implantation in the mare?
Animal Reproduction Science, 2010 The majority of early pregnancy losses in the mare occur between days 15 and 45 of gestation, i.e. the period in which the conceptus must form a stable attachment with the endometrium (Allen, 2001). At present, little is known about the pathways that regulate equine implantation, orhow‘implantation failure’ contributes to pregnancy loss. Leukemia
Villani, M. +3 more
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LIF: Not Just a Leukemia Inhibitory Factor*
Endocrine Reviews, 1991Increasingly it seems that many cytokines are pleiotropic, and individual molecules may have critical roles in several different organ systems. LIF exemplifies this phenomenon: it influences embryogenesis, bone and lipid metabolism, and hematopoietic and nervous system function. Many of LIF's effects are reminiscent of those of IL-1, TNF, and TGF-beta.
R, Kurzrock +4 more
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Leukemia inhibitory factor (LIF) inhibits angiogenesis in vitro
Journal of Cell Science, 1995ABSTRACT Using an in vitro model in which endothelial cells can be induced to invade a three-dimensional collagen gel to form capillary-like tubular structures, we demonstrate that leukemia inhibitory factor (LIF) inhibits angiogenesis in vitro.
M S, Pepper +3 more
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The leukemia inhibitory factor (LIF)
The International Journal of Cell Cloning, 1991Leukemia inhibitory factor (LIF) is a glycoprotein able to enforce differentiation and/or suppress clonogenic self-renewal in a number of myeloid leukemic cell lines. When acting on normal embryonic stem cells, it has the opposite action of preventing differentiation commitment.
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