Results 11 to 20 of about 155,017 (308)

Acute Myeloid Leukemia in Suspected Sepsis after Caesarean Section [PDF]

open access: yesKorean Journal of Critical Care Medicine, 2014
The incidence of acute leukemia during pregnancy is extremely rare, and often it is not easy to differentiate it from other diseases associated with pregnancy such as sepsis or hemorrhage.
Myoung Hwa Kim   +6 more
doaj   +6 more sources

Acute Leukemia and Pregnancy

open access: yesEuropean Journal of Inflammation, 2007
The combination of acute leukemia and pregnancy is infrequent. It is estimated to occur in less than 1 in 75,000 pregnancies. Maternal and fetal outcomes have improved substantially in recent years.
V. Karagiannis   +6 more
doaj   +2 more sources

Clinicopathological evaluation of acute leukemias in a tertiary care hospital: a cross-sectional study [PDF]

open access: yesTurkish Journal of Pathology, 2021
Acute Myeloid Leukemia (AML) and Acute Lymphoblastic Leukemia (ALL) are clinically and biologically diverse phenotypic diseases amongst hematological malignancies. The current study objectives were to diagnose and classify cases of AL as per revised 4th edition of WHO 2016 classification of AL's and study their clinicopathological profiles.This cross ...
Gayatri N. PATEL   +4 more
openaire   +4 more sources

Chronic Myeloid Leukemia and Cesarean Section: The Anesthesiologist’s Point of View [PDF]

open access: yesCase Reports in Obstetrics and Gynecology, 2018
Background . Chronic Myeloid Leukemia (CML) is a myeloproliferative neoplasm related to chromosomal reciprocal translocation t(9;22). Tyrosine kinase inhibitors (TKIs) such as imatinib have drastically revolutionized the course and the prognosis of this hematologic malignancy.
Houssam Rebahi   +2 more
openaire   +4 more sources

AXL/MERTK inhibitor ONO-7475 potently synergizes with venetoclax and overcomes venetoclax resistance to kill FLT3-ITD acute myeloid leukemia

open access: yesHaematologica, 2021
FMS-like Tyrosine Kinase 3 (FLT3) mutation is associated with poor survival in acute myeloid leukemia (AML). The specific Anexelekto/MER Tyrosine Kinase (AXL) inhibitor, ONO-7475, kills FLT3-mutant AML cells with targets including Extracellular- signal ...
Sean M. Post   +16 more
doaj   +1 more source

Iron oxide nanoparticles in leukemia: design, diagnostic applications, and therapeutic strategies

open access: yesJournal of the Egyptian National Cancer Institute
Leukemia, a heterogeneous group of hematologic malignancies, poses significant challenges in terms of early diagnosis and effective treatment. Recent advancements in nanotechnology have paved the way for innovative approaches in leukemia management, with
Henry Fenekansi Kiwumulo   +6 more
doaj   +2 more sources

Concomitant targeting of FLT3 and BTK overcomes FLT3 inhibitor resistance in acute myeloid leukemia through the inhibition of autophagy

open access: yesHaematologica, 2022
Strategies to overcome resistance to FMS-like tyrosine kinase 3 (FLT3)-targeted therapy in acute myeloid leukemia (AML) are urgently needed.
Weiguo Zhang   +14 more
doaj   +1 more source

Combined inhibition of BCL-2 and MCL-1 overcomes BAX deficiency-mediated resistance of TP53-mutant acute myeloid leukemia to individual BH3 mimetics

open access: yesBlood Cancer Journal, 2023
TP53-mutant acute myeloid leukemia (AML) respond poorly to currently available treatments, including venetoclax-based drug combinations and pose a major therapeutic challenge.
Bing Z. Carter   +15 more
doaj   +1 more source

PLATELET INDICES IN LEUKEMIAS: - A CROSS SECTIONAL STUDY

open access: yesJournal of Medical Sciences, 2022
Objective: To evaluate the pattern of changes in the platelet indices in different Leukemias. Material and method: This descriptive cross-sectional study was conducted in the Pathology Department of Khyber Teaching Hospital from January 2021 to December 2021 (1-year duration).
Huma Riaz   +5 more
openaire   +1 more source

Paraffin Section Immunophenotyping of Acute Leukemias in Bone Marrow Specimens [PDF]

open access: yesAmerican Journal of Clinical Pathology, 1996
The immunohistochemical evaluation of acute leukemia specimens has been limited in the past due of the inability to detect many lineage-related antigens in paraffin sections. With the improvement in immunohistochemical methods as well as the introduction of new antibodies, these limitations are now reduced.
D A, Arber, K A, Jenkins
openaire   +2 more sources

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