Results 11 to 20 of about 155,038 (165)

Expression of the apelinergic system and its influence on functional properties of tumor cells

Genetics & Applications, 2021
mall peptide Apelin and its cognate receptor APJ, are known to play a role in tumor angiogenesis and overall cancer progession. Certain authors suggest that the Apelin receptor is also a factor in cancer immunotherapy.
Zoran Knezevic, Jasmin Wellbrock, Frauke Fuchs, Gabi Vohwinkel, Antonia Matzat, Walter Fiedler   +5 more
doaj   +1 more source

Blood group discrepancies in leukemia children: A cross sectional study.

The Professional Medical Journal, 2022
Objective: To Estimate the frequency of blood group discrepancies among Leukemia Children. Study Design: Cross Sectional study. Setting: University of Child Health Sciences, The Children Hospital Lahore. Period: October to January 2020. Material & Methods: This study was conducted among patients in CH and ICH Lahore, regarding ABO blood group ...
null Tooba Fateen, null Hammad Tufail Chaudhary, null Nazish Saqlain, null Sundus Arshad, null Nayab Anam, null Attiq ur Rehman, null Muhammad Ahsan   +6 more
openaire   +1 more source

Evaluation of oral health‐related quality of life in children with acute lymphocytic leukemia/acute myelocytic leukemia: A cross‐sectional study

Oral Diseases, 2023
Abstract Objective Chemotherapy and radiotherapy, used to treat childhood hematological malignancies (acute lymphocytic leukemia [ALL] and acute myelocytic leukemia [AML]) can negatively affect oral tissues and organs.
Munevver Kilic, Sevcihan Gunen Yilmaz, Zehra Merve Kockopru   +2 more
openaire   +3 more sources

Fatty Acid Metabolism, Bone Marrow Adipocytes, and AML

Frontiers in Oncology, 2020
Acute myeloid leukemia (AML) cells modulate their metabolic state continuously as a result of bone marrow (BM) microenvironment stimuli and/or nutrient availability. Adipocytes are prevalent in the BM stroma and increase in number with age.
Yoko Tabe, Yoko Tabe, Marina Konopleva, Michael Andreeff   +3 more
doaj   +1 more source

Turkish Chronic Myeloid Leukemia Study: Retrospective Sectional Analysis of CML Patients

The Turkish Journal of Hematology, 2013
here have been tremendous changes in treatment and follow-up of patients with chronic myeloid leukemia (CML) in the last decade. Especially, regular publication and updating of NCCN and ELN guidelines have provided enermous rationale and base for close monitorization of patients with CML.
Fahri Şahin, Güray Saydam, Melda Cömert, Burak Uz, Akif Selim Yavuz, Esra Turan, İpek Yönal, Hilmi Atay, Engin Keltikli, Mehmet Turgut, Mustafa Pehlivan, Olga Meltem Akay, Emel Gürkan, Semra Paydaş, Selda Kahraman, Fatih Demirkan, Onur Kırkızlar, Seval Akpınar, Gülsüm Emel Pamuk, Muzaffer Demir, Hasan Mücahit Özbaş, Mehmet Sönmez, Mine Gültürk, Ayşe Salihoğlu, Ahmet Emre Eşkazan, Cem Ar, Handan Şahin Haydaroğlu, Şeniz Öngören, Zafer Başlar, Yıldız Aydın, Mustafa Nuri Yenere, Nükhet Tüzüner, Burhan Ferhanoğlu, C. İbrahim Haznedaroglu, Osman İlhan, Teoman Soysal   +35 more
openaire   +9 more sources

Extended live-cell barcoding approach for multiplexed mass cytometry

Scientific Reports, 2021
Sample barcoding is essential in mass cytometry analysis, since it can eliminate potential procedural variations, enhance throughput, and allow simultaneous sample processing and acquisition.
Muharrem Muftuoglu, Li Li, Shaoheng Liang, Duncan Mak, Angelique J. Lin, Junxiang Fang, Jared K. Burks, Ken Chen, Michael Andreeff   +8 more
doaj   +1 more source

Baricitinib with cyclosporine eliminates acute graft rejection in fully mismatched skin and heart transplant models

Frontiers in Immunology, 2023
Solid organ transplant represents a potentially lifesaving procedure for patients suffering from end-stage heart, lung, liver, and kidney failure.
Ramzi Abboud, Sena Kim, Karl Staser, Reyka G. Jayasinghe, Sora Lim, Parmeshwar Amatya, C. Corbin Frye, Benjamin Kopecky, Julie Ritchey, Feng Gao, Kory Lavine, Daniel Kreisel, John F. DiPersio, Jaebok Choi   +13 more
doaj   +1 more source

Targeting MCL-1 dysregulates cell metabolism and leukemia-stroma interactions and re-sensitizes acute myeloid leukemia to BCL-2 inhibition

Haematologica, 2020
MCL-1 and BCL-2 are both frequently overexpressed in acute myeloid leukemia (AML) and critical for the survival of AML cells and AML stem cells. MCL-1 is a key factor in venetoclax resistance.
Bing Z. Carter, Po Yee Mak, Wenjing Tao, Marc Warmoes, Philip L. Lorenzi, Duncan Mak, Vivian Ruvolo, Lin Tan, Justin Cidado, Lisa Drew, Michael Andreeff   +10 more
doaj   +1 more source

DNA-PK inhibitor peposertib enhances p53-dependent cytotoxicity of DNA double-strand break inducing therapy in acute leukemia

Scientific Reports, 2021
Peposertib (M3814) is a potent and selective DNA-PK inhibitor in early clinical development. It effectively blocks non-homologous end-joining repair of DNA double-strand breaks (DSB) and strongly potentiates the antitumor effect of ionizing radiation (IR)
Eric Haines, Yuki Nishida, Michael I. Carr, Rafael Heinz Montoya, Lauren B. Ostermann, Weiguo Zhang, Frank T. Zenke, Andree Blaukat, Michael Andreeff, Lyubomir T. Vassilev   +9 more
doaj   +1 more source

Distinct protein signatures of acute myeloid leukemia bone marrow-derived stromal cells are prognostic for patient survival

Haematologica, 2018
Mesenchymal stromal cells (MSC) support acute myeloid leukemia (AML) cell survival in the bone marrow (BM) microenvironment. Protein expression profiles of AML-derived MSC are unknown.
Steven M. Kornblau, Peter P. Ruvolo, Rui-Yu Wang, V. Lokesh Battula, Elizabeth J. Shpall, Vivian R. Ruvolo, Teresa McQueen, YiHua Qui, Zhihong Zeng, Sherry Pierce, Rodrigo Jacamo, Suk-Young Yoo, Phuong M. Le, Jeffrey Sun, Numsen Hail, Marina Konopleva, Michael Andreeff   +16 more
doaj   +1 more source