Results 41 to 50 of about 155,038 (165)

Venetoclax for AML: changing the treatment paradigm

open access: yesBlood Advances, 2019
: Venetoclax is a specific B-cell lymphoma-2 (BCL-2) inhibitor that can restore activation of apoptosis in malignancies, the survival of which depends on dysregulation of this pathway.
Daniel A. Pollyea   +3 more
doaj   +1 more source

Knowledge, attitude, and practice toward leukemia in the general population and among family members of patients with leukemia: A cross-sectional study

open access: yesHeliyon
Patients with leukemia rely on social and family support. This study aimed to explore the knowledge, attitude, and practice (KAP) toward leukemia among family members of patients with leukemia and the general population in southeast China.A cross-sectional study was conducted in September 2022 in southeast China (Anhui Province).
Fengbo Jin   +6 more
openaire   +3 more sources

A cross-sectional analysis of the global burden of childhood leukemia from 1990 to 2021

open access: yesJournal of Cancer Research and Clinical Oncology
Childhood leukemia is a common malignant tumor worldwide, affecting survival rates and posing medical and public health challenges. Assessing its global burden is essential for informing prevention, treatment, and policy efforts.This is a cross-sectional study based on data from the 2021 Global Burden of Disease (GBD) study, covering the years 1990 to ...
Wang, Ping   +8 more
openaire   +2 more sources

Anesthesiologic management of cesarean section at 35-weeks pregnancy with acute myeloid leukemia and profound thrombocytopenia refractory to platelet transfusion: A case report

open access: yesJournal of Obstetric Anaesthesia and Critical Care, 2020
Leukemia is a very rare condition in pregnancy. The pathology itself poses a great challenge to the anesthesiologist due to the inherent risks such as blast crisis, tumor lysis syndrome, anemia, and thrombocytopenia.
Jemea Bonaventure   +3 more
doaj   +1 more source

Sleep Disturbances in Survivors of Childhood Acute Lymphoblastic Leukemia: A Cross-Sectional Study

open access: yesIndian Pediatrics
Survivors of childhood cancer are at risk of sleep disturbances, an often, neglected aspect of holistic health. This study was carried out to determine the prevalence of sleep disturbances in survivors of pediatric acute lymphoblastic leukemia (ALL) and to identify any risk factors for the same.Survivors of ALL aged 6-18 years, who had completed their ...
Kanwaljeet Kaur Chopra   +6 more
openaire   +2 more sources

Inhibition of menin, BCL-2, and FLT3 combined with a hypomethylating agent cures NPM1/FLT3-ITD/-TKD mutant acute myeloid leukemia in a patient-derived xenograft model

open access: yesHaematologica, 2023
Bing Z. Carter   +8 more
doaj   +1 more source

Evaluating measurable residual disease in acute myeloid leukemia

open access: yesBlood Advances, 2018
: Mounting evidence indicates that the presence of measurable (“minimal”) residual disease (MRD), defined as posttherapy persistence of leukemic cells at levels below morphologic detection, is a strong, independent prognostic marker of increased risk of ...
Farhad Ravandi   +2 more
doaj   +1 more source

Pruritus as a Presenting Symptom of FIP1L1-PDGFRA-Positive Chronic Eosinophilic Leukemia

open access: yesJournal of Blood Medicine, 2021
Mohammad Abu-Tineh,1 Esra’a Aljaloudi,2 Mohamed A Yassin1 1Department of Oncology- Hematology and BMT Section, National Center for Cancer Care and Research, Hamad Medical Corporation, Doha, Qatar; 2Department of Family Medicine, Hamad Medical Corporation,
Abu-Tineh M, Aljaloudi E, Yassin MA
doaj  

Correction: Combined inhibition of BCL-2 and MCL-1 overcomes BAX deficiency-mediated resistance of TP53-mutant acute myeloid leukemia to individual BH3 mimetics

open access: yesBlood Cancer Journal, 2023
Bing Z. Carter   +15 more
doaj   +1 more source

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