Results 121 to 130 of about 152,467 (287)

Advanced Pharmaceutical Nanotechnologies Applied for Chinese Herbal Medicines

Advanced Science, EarlyView.
This review offers a comprehensive overview of pharmaceutical nanotechnology strategies to address limitations associated with the complex material basis and relative mild therapeutic efficacy of Chinese herbal medicines, and summarizes the advantages of these strategies.
Jiameng Li, Ya‐Li Zhang, Tong Jin, Zhaokui Jin, Mengliang Zhu, Guangchao Qing, Jinchao Zhang, Zhisen Wang, Yan Mu, Jin Li, Qian Hua, Xing‐Jie Liang   +11 more
wiley   +1 more source

Sero-prevalence of bovine Leukemia virus in cattle from Caquetá state, Colombia

Revista Colombiana de Ciencia Animal Recia, 2019
Bovine Leukemia Virus (BLV) is the agent of enzootic bovine leukosis (EBL), this disease is a neoplasm of lymphatic tissue in bovine species.  The aim of this article was determinate the prevalence of bovine leukemia virus in dual-purpose cattle from ...
Pablo Andrés Motta-Delgado, Luis Gabriel Rivera-Calderón, Wilmer Herrera-Valencia, Ricardo Alberto Martínez-Tovar, Marliyanini Londoño-Sánchez, Erika Paola Rojas-Vargas, Angie Liseth Muñoz-Murcia, María Elodia Gutiérrez-Quintero   +7 more
doaj   +1 more source

Purification and characterization of a protein-tyrosine kinase encoded by the Abelson murine leukemia virus [PDF]

, 1985
Sequences termed v-abl, which encode the protein-tyrosine kinase activity of Abelson murine leukemia virus, have been expressed in Escherichia coli as a fusion product (ptabl50 kinase).
Baltimore, David, Chow, Marie, Foulkes, J. Gordon, Frackelton, A. Raymond, Jr., Gorka, Carolyn   +4 more
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Bovine leukemia virus DNA associated with breast cancer in women from South Brazil

Scientific Reports, 2019
Breast cancer is a neoplastic condition with a high morbidity and mortality amongst women worldwide. Recent data linking bovine leukemia virus (BLV) with breast cancer has been contested already.
D. Schwingel, A. P. Andreolla, L. M. S. Erpen, R. Frandoloso, L. Kreutz   +4 more
semanticscholar   +1 more source

A Super‐Enhancer‐Driven Transcriptional Regulatory Circuit Underlying Abiraterone Resistance in Castration‐Resistant Prostate Cancer

Advanced Science, EarlyView.
This study identifies a super‐enhancer‐driven transcriptional regulatory circuit comprising BCL6, SMAD3, and NFIB that cooperate to drive cholesterol synthesis via SREBF2/HMGCR/FDFT1 activation and regulate CDK2/CCND3 for cell cycle control. Targeting this circuit with BI‐3802 or downstream inhibitors (Fatostatin/Lovastatin) overcomes abiraterone ...
Liling Jiang, Jiamin Wang, Guanjie Peng, Haichuan Zhang, Jinxin Fang, Yingyin Gao, Enzhe Lou, Yangzhou Liu, Wa Ding, Bingyuan Liu, Qiong Mao, Lizhen Jiang, Aochu Liu, Xinyue Li, Shiwen Hu, Qiaomin Ma, Yueyuan Zheng, Zhigang Zhao, Xianping Shi   +18 more
wiley   +1 more source

Review: Risks of disease transmission through semen in cattle

Animal, 2018
The purpose of this paper is to review scientific evidence concerning pathogens that could potentially be transmitted via bovine semen. As a result of a careful analysis of the characteristics of infections that may cause transmission of disease through ...
M.D. Givens
doaj  

Controlling bovine leukemia virus in dairy herds by identifying and removing cows with the highest proviral load and lymphocyte counts.

Journal of Dairy Science, 2019
The objective of this field trial was to reduce bovine leukemia virus (BLV) transmission and prevalence in commercial dairy herds using proviral load (PVL) and lymphocyte count (LC) measurements as indicators of the most infectious animals for culling or
Vickie J Ruggiero, Bo Norby, O. J. Benitez, H. Hutchinson, K. Sporer, C. Droscha, Cheryl L. Swenson, Paul C. Bartlett   +7 more
semanticscholar   +1 more source

Combining PIM‐2 and PARP1 Inhibitors Induces MICA Expression on Multiple Myeloma Cells to Activate NK Cells through NKG2D Binding

Advanced Science, EarlyView.
The findings suggest that the combination of PIM‐2 and PARP1 inhibitors can induce MICA expression on MM cells, thereby activating NK cells through NKG2D binding. This process may restore NK cell function and serve as a potential therapeutic approach for MM patients. Abstract While immunogenic death in tumor cells activates specific anti‐tumor T cells,
Zhaoyun Liu, Wenhui Lei, Xiaohan Liu, Hui Liu, Kai Ding, Jia Song, Rong Fu   +6 more
wiley   +1 more source

Using a Herd Profile to Determine Age-Specific Prevalence of Bovine Leukemia Virus in Michigan Dairy Herds

Veterinary Medicine International, 2012
Enzootic bovine leukosis is a contagious disease of cattle caused by the retrovirus, bovine leukemia virus (BLV) and is the most common cause of malignant neoplasm in cattle.
Ronald J. Erskine, Paul C. Bartlett, Todd M. Byrem, Chelsea L. Render, Catherine Febvay, Jessica T. Houseman   +5 more
doaj   +1 more source

Preparation of anti-idiotypic antibodies for the diagnosis of bovine leukemia [PDF]

, 2014
The basic components of the diagnostic test systems are antigens and specific antibodies. The main objective of developing express tests for the diagnosis of bovine leukemia virus (BLV) is to obtain a virus antigen drug, which is very time-consuming to
Borovikov, S. N., Kiyan, V., Shramko, A.
core