Results 41 to 50 of about 112,142 (249)

Multiple oncogenic viruses are present in human breast tissues before development of virus associated breast cancer

Infectious Agents and Cancer, 2017
Background Multiple oncogenic viruses including, mouse mammary tumor virus, bovine leukemia virus, human papilloma virus, and Epstein Barr virus, have been identified as separate infectious pathogens in human breast cancer. Here we demonstrate that these
James S. Lawson, Wendy K. Glenn
doaj   +1 more source

Detection of genetic material of causative agents of animal viral diseases in blood-sucking dipterans from the Tyumen Region

Российский паразитологический журнал, 2023
The purpose of the research is to test blood-sucking dipterans collected in the Tyumen Region for genetic material of viruses that cause dangerous diseases in live-stock animals.Materials and methods.
K. S. Krutko, A. G. Kinareikina, M. I. Serkova, E. A. Silivanova, O. A. Fedorova   +4 more
doaj   +1 more source

The effect of bovine BST2A1 on the release and cell-to-cell transmission of retroviruses

Virology Journal, 2017
Background Human BST2 (hBST2, also called Tetherin) is a host restriction factor that blocks the release of various enveloped viruses. BST2s from different mammals also possess antiviral activity.
Zhibin Liang, Yang Zhang, Jie Song, Hui Zhang, Suzhen Zhang, Yue Li, Juan Tan, Wentao Qiao   +7 more
doaj   +1 more source

Enhancement of vaccinia virus based oncolysis with histone deacetylase inhibitors [PDF]

, 2010
Histone deacetylase inhibitors (HDI) dampen cellular innate immune response by decreasing interferon production and have been shown to increase the growth of vesicular stomatitis virus and HSV.
Atkins, H, Bell, JC, Breitbach, C, Cox, J, De Silva, N, Diallo, JS, Falls, T, Guimond, T, Huang, B, Kirn, D, Le Boeuf, F, MacTavish, H, McCart, AJ, Simmons, JG, Stanford, M, Thorne, S   +15 more
core   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

Effect of dry pasteurized milk from cows infected with the leukemia virus on the development of malignant tumors

Ветеринария и кормление
The article presents experimental data on the reproduction of a muscular solid tumor in BALB/c mice and the study of dried milk from leukemia virus-infected cows after long-term pasteurization effect on the development of these tumors.
Laskavyy V.N. , Polyanina T.I., Laskavaya V.V. , Tarasenko T.N.   +3 more
doaj   +1 more source

Diagnosis and Early Prediction of Lymphoma Using High-Throughput Clonality Analysis of Bovine Leukemia Virus-Infected Cells

Microbiology Spectrum, 2022
Bovine leukemia virus (BLV), a retrovirus, infects B cells of ruminants and is integrated into the host genome as a provirus for lifelong infection. After a long latent period, 1% to 5% of BLV-infected cattle develop aggressive lymphoma, enzootic bovine ...
Tomohiro Okagawa, Honami Shimakura, Satoru Konnai, Masumichi Saito, Takahiro Matsudaira, Naganori Nao, Shinji Yamada, Kenji Murakami, Naoya Maekawa, Shiro Murata, Kazuhiko Ohashi   +10 more
doaj   +1 more source

T Cell Glycoengineering to Modulate Immune‐Tumor Crosstalk: A Universal Non‐Genetic Strategy for Enhanced Tumor Immunotherapy

Advanced Science, EarlyView.
This study describes a T cell surface engineering strategy that integrates polymer materials with tumor immunology, aiming to achieve broad‐spectrum anti‐tumor applications of glycopolymer‐engineered T (G‐T) cells via non‐genetic modification. Glycopolymer engineering generally modulates immune‐tumor crosstalk through specific cell‐cell interactions ...
Lihua Yao, He Yang, Fangjian Shan, Xiaomeng Niu, Yichen Wang, Hengyuan Zhang, Sujian Wang, Gaojian Chen, Hong Chen   +8 more
wiley   +1 more source

Influence of radioactive isotopes ⁹⁰Sr, ¹³⁷Cs, ²¹⁰Pb on environmental objects and their relationship with bovine leukemia in ecosystems of the Republic of Dagestan

Юг России: экология, развитие, 2022
Aim. To conduct studies on the content of radionuclides 90Sr, 137Cs, 210Pb and determine the total beta‐activity in objects (samples) of the external environment, as well as to investigate the effect of radioactive isotopes on the spread of bovine ...
A. R. Mustafayev, E. A. Ivashev
doaj   +1 more source

Three‐Year Follow‐Up of Neoadjuvant Tislelizumab with Chemotherapy in Locally Advanced Gastric and Gastroesophageal Junction Adenocarcinoma: Revealing Cancer‐Associated Fibroblast Heterogeneity Corresponding to PD‐1 Blockade Efficacy

Advanced Science, EarlyView.
Heterogeneous cancer‐associated fibroblasts orchestrate dual immune microenvironments in LAGC. Abstract The potential for immunotherapy in patients with locally advanced gastric cancer (LAGC) is recently confirmed. To report the 3‐year follow‐up data are aimed from a novel clinical trial. This is a prospective single‐arm phase II trial.
Yao Lin, Xiong Sun, Chengguo Li, Ming Yang, Ke Wu, Ke Liu, Anshu Li, Xiaoming Shuai, Kailin Cai, Zheng Wang, Guobin Wang, Peng Zhang, Jianfeng Shen, Kaixiong Tao, Yuping Yin   +14 more
wiley   +1 more source