Results 41 to 50 of about 61,162 (207)

Bovine Leukemia Virus Involvement In Enzootic Bovine Leukosis

, 1978
Publisher Summary Enzootic bovine leukosis is a contagious disease induced by bovine leukemia virus (BLV). It is a chronic disease that develops over a long period and can be schematically divided into three phases: (1) from birth to infection (some animals are already infected at birth), (2) from viral infection to tumorous transformation (a number ...
Burny, Arsène, Bex, Françoise, Chantrenne, Hubert, Cleuter, Yvette, Dekegel, Daniel, Ghysdael, Jacques, Kettmann, Richard, Leclercq, M, Leunen, Joseph, Mammerickx, Marc, Portetelle, Daniel   +10 more
openaire   +3 more sources

Stage‐Adaptive Janus Microneedle System for Redox‐Immune Regulation and Mitochondrial Protection in Infected Diabetic Wound Healing

Advanced Science, EarlyView.
ABSTRACT Infected diabetic wounds are sustained by a vicious cycle of hyperglycemia‐driven bacterial infection, persistent oxidative stress, and excessive inflammation, which collectively disrupt the ordered progression of tissue repair. Here, we engineered a stage‐adaptive Janus microneedle patch (MN‐FeSAC‐PPE) to enable a staged therapeutic process ...
Mengting Yin, Yu Zhang, Xinyu Qu, Jiayi Liu, Zhongyi Sun, Haibo Liu, Ziyan Chen, Jing Ru, Jingwen Han, Bingqiang Lu, Yan Lu, Yan Wang, Xinyu Zhao, Feng Chen   +13 more
wiley   +1 more source

ДИАГНОСТИЧЕСКАЯ ОЦЕНКА СЕРОЛОГИЧЕСКОГО И МОЛЕКУЛЯРНОГЕНЕТИЧЕСКОГО МЕТОДОВ ЛАБОРАТОРНЫХ ИССЛЕДОВАНИЙ НА РЕТРОВИРУСНЫЕ ИНФЕКЦИИ КРУПНОГО РОГАТОГО СКОТА

Ветеринарная патология, 2013
It is established that the infection rate of bovine immunodeficiency virus and bovine leukemia virus in farms of the Saratov region is rather high (68.7% and 65,2%, respectively), the combined infection by both retroviruses is registered in 52,5% of ...

doaj  

Effect of bovine leukemia virus on bovine mammary epithelial cells [PDF]

Virus Research, 2019
Bovine leukemia virus (BLV) is a retrovirus that infects cattle and is associated with an increase in secondary infections. The objective of this study was to analyze the effect of BLV infection on cell viability, apoptosis and morphology of a bovine mammary epithelial cell line (MAC-T), as well as Toll like receptors (TLR) and cytokine mRNA expression.
Martinez Cuesta, Lucia, Nieto Farías, María Victoria, Lendez, Pamela Anahí, Rowland, Raymond R. R., Sheahan, Maureen A., Cheuquepán Valenzuela, Felipe Andrés, Marin, Maia Solange, Dolcini, Guillermina Laura, Ceriani, Maria Carolina   +8 more
openaire   +3 more sources

Discovery and Engineering of a Rat Endogenous Retrovirus Reverse Transcriptase for Efficient Prime Editing

Advanced Science, EarlyView.
We screened 558 reverse transcriptases and engineered an optimized rat endogenous retrovirus‐derived variant, enRERV‐RT, via structure‐guided engineering and deep mutational scanning. This enhanced prime editor, based on the engineered RT, outperforms conventional M‐MLV‐RT systems across plant and animal cells, particularly at hard‐to‐edit loci ...
Linsha Ma, Pengcheng Yao, Shengqi Wu, Yuanyuan Shi, Lang Qin, Baitao Li, Jiayi Zhu, Minhua Huang, Yichong Zhu, Yuwen Song, Jinhuan Pang, Ziping Guo, Guochuan Wu, Chen Wang, Kewei Xu, Ruihua Huang, Quan Kuang, Liang Qu, Changtian Pan, Xianrong Xie, Qinlong Zhu, Jiaying Huang, Qiupeng Lin   +22 more
wiley   +1 more source

MODERN METHODS AND EXPERIENCE OF STRUGGLE AGAINST LEUKEMIA OF CATTLE

В мире научных открытий, 2018
The article presents the main methods of diagnosis and control of the bovine leukemia virus currently used. The wide spread of the disease is due to a fairly easy transmission of the virus, the lack of early diagnosis, vaccination and treatment ...
Tatyana Vladimirovna Zubova, Vladimir Alexandrovich Pleshkov, Alexander Nikolaevich Mironov   +2 more
doaj   +1 more source

PRMT9 Aggravated Dopaminergic Neurodegeneration in Parkinson's Disease Model by Facilitating the Degradation of DUSP26 and Inducing Mitochondrial Dysfunction

Advanced Science, EarlyView.
In the pathological state of PD induced by MPP+, the upregulated PRMT9 in dopaminergic neurons translocates into mitochondrion and interacts with DUSP26 and catalyzes its arginine methylation, leading to the ubiquitin‐proteasomal degradation of DUSP26 mediated by Trim32.
Tengfei Liu, Xiaomeng Song, Xin Guo, Rui Xiao, Ru Sun, Qiuran Ji, Lu Yu, Yiquan Li, Qingyi Fu, Qidi Xue, Lingjun Kong, Lin Chen, Chengjiang Gao, Huiqing Liu   +13 more
wiley   +1 more source

Генетическое разнообразие вируса лейкоза крупного рогатого скота и его распространение в районах Республики Дагестан

Юг России: экология, развитие
To study the spread of infection caused by the bovine leukemia virus in farms of the Republic of Dagestan.PCR diagnostics of 212 cattle blood samples collected in farms of the Kizlyarsky, Kumtorkalinsky and Tabasaransky districts was performed for the ...
D. A. Baboshko, M. G. Daudova, P. Y. Achigecheva, K. A. Elfimov, D. K. Dandamaev, Z. R. Shakhbanova, A. V. Totmenin, N. M. Gashnikova   +7 more
doaj   +1 more source

Pathobiology of bovine leukemia virus.

Veterinary research, 1994
Bovine leukemia virus (BLV) is a retrovirus similar to the human T-cell leukemia virus (HTLV). Most BLV infected animals (70%) develop a B-cell lymphoproliferative syndrome with altered productive traits and 1 to 5% die with B-cell lymphosarcomas. Although BLV infection is world-wide, western European countries have almost eradicated it by slaughtering
Schwartz-Cornil, Isabelle, Levy, Danielle   +1 more
openaire   +4 more sources

8‐Oxoguanine Modified CircMTUS1 Drives PABPC1 Phase Separation to Promote Gastric Cancer Progression and Cisplatin Resistance via Autophagy

Advanced Science, EarlyView.
ABSTRACT Gastric cancer (GC) is a major global health concern, as its prevention and treatment remain significant challenges. The 8‐oxoguanine (o8G) modification of circRNAs, alongside their capacity to orchestrate liquid‐liquid phase separation (LLPS) and autophagy, plays a pivotal role in driving tumor progression and determining therapeutic outcomes.
Lei Peng, Lurong Li, Zhenghui Zhu, Chenyang Li, Huaiming Sang, Guoxin Zhang, Xuan Li, Yini Dang, Yuanyuan Li   +8 more
wiley   +1 more source