Characterization of a leukocidin identified in Staphylococcus pseudintermedius. [PDF]
PLoS ONE, 2018 Bacterial infections from Staphylococcus pseudintermedius are the most common cause of skin infections (pyoderma) affecting dogs. Two component pore-forming leukocidins are a family of potent toxins secreted by staphylococci and consist of S (slow) and F
Mohamed A Abouelkhair +4 more
doaj +4 more sources
Panton-Valentine Leukocidin and Staphyloccoccal Skin Infections in Schoolchildren
Emerging Infectious Diseases, 2004 The Panton-Valentine leukocidin is associated with staphylococcal skin and pulmonary infections. We describe a school outbreak of skin infections and the public health response to it.
Karim Boubaker +6 more
doaj +5 more sources
Panton-Valentine Leukocidin–Positive MRSA, Shanghai
Emerging Infectious Diseases, 2010 To the Editor: The development of methicillin resistance in community strains of Staphylococcus aureus is a notable step in the evolution of this pathogen. Unlike their equivalents in the hospital environment, community-associated methicillin-resistant S.
Li-Zhong Han +7 more
doaj +3 more sources
Panton-Valentine Leukocidin Genes in Staphylococcus aureus
Emerging Infectious Diseases, 2006 The pathogenicity of Staphylococcus aureus depends on various bacterial surface components and extracellular proteins. However, the precise role of single virulence determinants in relation to infection is hard to establish. The frequent recovery of staphylococcal isolates that produce leukocidal toxins from patients with deep skin and soft tissue ...
Damian C. Melles +5 more
doaj +4 more sources
Panton-Valentine Leukocidin–producing Staphylococcus aureus
Emerging Infectious Diseases, 2006 To the Editor: Panton-Valentine leukocidin (PVL) is a cytotoxin produced by Staphylococcus aureus that causes leukocyte destruction and tissue necrosis (1). Although produced by
Amos Adler +4 more
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Necrotizing Pneumonia Caused by PVL-Negative Methicillin-Susceptible <i>Staphylococcus aureus</i> Complicated by Refractory Pneumothorax: A Case Report. [PDF]
Respirol Case RepHere we report a case of PVL‐negative MSSA necrotizing pneumonia in a previously healthy man that rapidly progressed to cavitary lesions and refractory pneumothorax. Despite its improvement after clindamycin‐based therapy, the patient experienced recurrent pneumothorax and chronic respiratory failure.
Endo S +4 more
europepmc +2 more sources
Clindamycin and daptomycin failure in PVL-positive MRSA infection of the skin and soft tissue. [PDF]
J Dtsch Dermatol GesJDDG: Journal der Deutschen Dermatologischen Gesellschaft, Volume 24, Issue 5, Page 674-676, May 2026.
Zolotas M +4 more
europepmc +2 more sources
Mode of Action of Staphylococcal Leukocidin: Relationship between Binding of 125 I-Labeled S and F Components of Leukocidin to Rabbit Polymorphonuclear Leukocytes and Leukocidin Activity [PDF]
Infection and Immunity, 1981 The binding of 125 I-labeled S component to rabbit polymorphonuclear leukocytes was found to be concentration dependent and saturable at 37°C. Scatchard analysis of the binding curve gave a straight line, indicating that S component binds to a single population of sites. The dissociation constant,
M, Noda +3 more
openaire +2 more sources
New targets for leukocidins [PDF]
Nature Reviews Microbiology, 2019 This study shows that staphylococcal leukocidins target endothelial cells to cause host lethality.
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Binding of pseudomonal leukocidin to rabbit polymorphonuclear leukocytes [PDF]
Infection and Immunity, 1984 The leukocytotoxic toxin pseudomonal leukocidin, produced by Pseudomonas aeruginosa, was radioiodinated with chloramine-T reagent. Binding of [125I]leukocidin to rabbit polymorphonuclear leukocytes was found to be concentration dependent at 37 degrees C.
T, Hirayama +4 more
openaire +2 more sources