Results 61 to 70 of about 15,006 (243)
Binding of pseudomonal leukocidin to rabbit polymorphonuclear leukocytes [PDF]
Infection and Immunity, 1984 The leukocytotoxic toxin pseudomonal leukocidin, produced by Pseudomonas aeruginosa, was radioiodinated with chloramine-T reagent. Binding of [125I]leukocidin to rabbit polymorphonuclear leukocytes was found to be concentration dependent at 37 degrees C.
T, Hirayama +4 more
openaire +2 more sources
Molecular mechanism of leukocidin GH–integrin CD11b/CD18 recognition and species specificity
Proceedings of the National Academy of Sciences of the United States of America, 2019 Significance Staphylococcus aureus is one of the most virulent bacterial pathogens and, in particular, has the richest repertoire of cytotoxins: A single bacterium can secrete 6 different β-barrel pore-forming toxins, with different cell type and species
N. Trstenjak +7 more
semanticscholar +1 more source
Journal of Medical Case Reports, 2011 Introduction Certain Staphylococcus aureus strains produce Panton-Valentine leukocidin, a toxin that lyses white blood cells causing extensive tissue necrosis and chronic, recurrent or severe infection.
Rao AV +5 more
doaj +1 more source
Prevalence of Genes Encoding Bi-Component Leukocidins among Clinical Isolates of Methicillin–Resistant Staphylococcus aureus [PDF]
Iranian Journal of Public Health, 2010 Background: Staphylococcus aureus has been recognized as a major human pathogen and is the major cause of nosocomial infections. Gamma-toxin, leukocidin and other bi-component toxins are a family of proteins encoded by the hlg and luk-PV, respectively ...
SA Havaei +3 more
doaj +1 more source
Prevalence of Panton-valentine gene in Staphylococcus aureus isolated from clinical samples and healthy carriers in Gorgan city, north of Iran [PDF]
, 2015 Aim. Staphylococcus aureus (S. aureus) is a nosocomial and community acquired pathogen. S. aureus is a pathogen that causes several types of disease from skin infections to systemic diseases that is because of having several virulence factors such as ...
Ghaemi, E. +3 more
core
The cell envelope of Staphylococcus aureus selectively controls the sorting of virulence factors
Nature Communications, 2021 The pathogen Staphylococcus aureus releases several pore-forming toxins, termed leukocidins, that kill immune cells. Here, Zheng et al. show that the retention of a leukocidin on bacterial cells and its release are modulated by lipoteichoic acid and a ...
Xuhui Zheng +6 more
doaj +1 more source
Zoonoses and Public Health, EarlyView.ABSTRACT Introduction The emergence of methicillin‐resistant Staphylococcus species (MRS) poses a growing threat to both human and veterinary health. Methods We performed a comparative genomic characterisation of 49 methicillin‐resistant Staphylococcus isolates collected from humans, dogs, and cats in a veterinary hospital from Central Chile.
Daniel Garrido +7 more
wiley +1 more source
Host-pathogen interactions in invasive Staphylococcus aureus infections [PDF]
, 2016 Staphylococcus aureus is a versatile human pathogen causing a wide range of diseases from uncomplicated skin and soft tissue infections to life-threatening invasive diseases like endocarditis, bacteremia, necrotizing pneumonia, and fasciitis.
Mairpady Shambat, Srikanth
core +1 more source
Diverse immunological roles of liver‐resident immune cells in liver diseases
Precision Medical Sciences, Volume 15, Issue 1, Page 4-17, March 2026.Based on their origin and functional characteristics, LRICs can be classified into four categories. These cells differ in the focus of their immune functions in liver diseases, yet all exhibit the characteristic of functional bidirectionality.
Zhengyi Fan +4 more
wiley +1 more source
Staphylococcal leukocidin and .GAMMA.-hemolysin.
Nippon Saikingaku Zasshi, 1997 極めて相同性の高い一次構造を持つ2種類の蛋白質が, 数個のアミノ酸残基の相違により全く異なった機能を持つという事実が Staphylococcus aureus の二成分蛋白毒素ロイコシジンならびにγヘモリジンにおいて明らかにされた。両者は, それぞれヒト白血球および赤血球上で孔を形成する蛋白毒素であるが, ロイコシジンの LukS 成分が, プロテインキナーゼA認識蛋白質であり, 本毒素成分のリン酸化と毒素活性特異性とに強い相関があることが明らかになった。また Panton-Valentine ロイコシジン遺伝子 (lukF-PVおよび lukS-PV) はφPVLと命名された S.
openaire +3 more sources