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SSR42 is a novel regulator of cytolytic activity in <i>Staphylococcus aureus</i>. [PDF]
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Panton-Valentine leukocidin: raising practitioner awareness
British Journal of Community Nursing, 2007Media reports have focused recently on methicillin resistant Staphylococcus aureus (MRSA). Panton-Valentine leukocidin is a toxin carried by MRSA. With reported increases in community acquired MRSA, This article seeks to raise practitioner awareness of this toxin and it’s effects on dermal tissue. A case study and anecdotal evidence is given.
Michelle, Beer, Mair, Fear
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Crystallization and properties of staphylococcal leukocidin
Biochimica et Biophysica Acta (BBA) - General Subjects, 1980Two components (F and S) of leukocidin were isolated and purified from broth culture of V8 strain of Staphylococcus aureus. There was loss of leukocidin activity during the separation, which was regained by mixing the components. Each component was apparently homogeneous by several criteria. The F and S components were crystallized (by salting out with
M, Noda +3 more
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Panton-Valentine leukocidin-positive osteoarticular infections
Médecine et Santé Tropicales, 2015The aim of our study was to evaluate the frequency of osteoarticular infections with Panton-Valentine leukocidin-positive (PVL) Staphylococcus aureus (PVL-SA) among patients admitted to the orthopedic ward at the Sahloul University Hospital (Sousse, Tunisia) and to study the characteristics of these strains and patients.We conducted a retrospective ...
C, Chaouch +5 more
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Staphylococcal Leukocidin, Panton-Valentine Type
Journal of Toxicology: Toxin Reviews, 1985AbstractThe Panton-Valentine leukocidin produced by most strains of S. aureus attacks polymorphonuclear leukocytes and macrophages but not other cell types. The toxin, discovered by van de Velde in 1894, was distinguished clearly from leukocyte-damaging hemolysins by the studies of Panton and Valentine. Purified for the first time by Woodin in 1960, it
Piotr L. Grójec, Janusz Jeljaszewicz
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Partial characterization of leukocidin from fusobacterium necrophorum
Zentralblatt für Bakteriologie, Mikrobiologie und Hygiene. Series A: Medical Microbiology, Infectious Diseases, Virology, Parasitology, 1986Leukocidin from Fusobacterium necrophorum was produced in the diffusate of a dialysis culture. It was free from deoxyribonuclease, fibrinolysin, gelatinase, haemolysin, lipase, caseinase and endotoxin. The leukocidin had a molecular weight between 10,000 and 5,000 as estimated by membrane partition chromatography.
M, Kanoe +3 more
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Effect of staphylococcal leukocidin on mouse leukocyte system
Zentralblatt für Bakteriologie, Mikrobiologie und Hygiene. 1. Abt. Originale. A, Medizinische Mikrobiologie, Infektionskrankheiten und Parasitologie, 1981Staphylococcal Panton-Valentine leukocidin has been purified and tested in mice for its biological properties. Applied even in high doses the leukocidin was not lethal. It caused however, disturbances in the peripheral blood occurring in several phases.
P L, Grójec, J, Jeljaszewicz
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Biological and Biochemical Characteristics of Fusobacterium necrophorum Leukocidin
American Journal of Veterinary Research, 1978SUMMARY The production of a leukocidal exotoxin by 18-hour dialysis cultures of Fusobacterium necrophorum was detected in vitro by a cytotoxicity assay, using bovine leukocytes isolated from peripheral blood. Biological characteristics were determined while maximizing the in vitro assay.
J E, Coyle-Dennis, L H, Lauerman
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Pragmatic management of Panton–Valentine leukocidin-associated staphylococcal diseases
International Journal of Antimicrobial Agents, 2011Panton-Valentine leukocidin (PVL)-producing Staphylococcus aureus is associated with a broad spectrum of diseases, ranging from common uncomplicated soft tissue infections to severe diseases such as complicated soft tissue infections, extensive bone and joint infections, and necrotising pneumonia.
Y, Gillet +8 more
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Leukocidins and gamma lysins (Staphylococcus sp.)
1997Abstract Staphylococcus aureus strains produce two kinds of bi¬ component toxins designated as leukocidins and γ-lysins (Freer and Arbuthnott 1983; Noda and Kato 1991).The Panton-Valentine (PV) leukocidins are two single polypeptide chains of 32 and 34.5 kD, called LukS and LukF respectively (S and F stand for slow and fast eluting ...
M Ferraras, G Menestrina
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