Results 91 to 100 of about 1,708,388 (381)

L-selectin mediated leukocyte tethering in shear flow is controlled by multiple contacts and cytoskeletal anchorage facilitating fast rebinding events [PDF]

PNAS 101: 6940-6945 (2004), 2005
L-selectin mediated tethers result in leukocyte rolling only above a threshold in shear. Here we present biophysical modeling based on recently published data from flow chamber experiments (Dwir et al., J. Cell Biol. 163: 649-659, 2003) which supports the interpretation that L-selectin mediated tethers below the shear threshold correspond to single L ...
arxiv   +1 more source

The impact of platelet indices on clinical outcome in heart failure: results from the MyoVasc study

ESC Heart Failure, 2021
Aims Platelet indices have been associated with traditional cardiovascular risk factors, cardiovascular diseases and all‐cause mortality. This study aimed to investigate the role of platelet count, mean platelet volume (MPV) and platelet‐to‐leukocyte ...
Bianca Dahlen, Andreas Schulz, Sebastian Göbel, Sven‐Oliver Tröbs, Sören Schwuchow‐Thonke, Henri M. Spronk, Jürgen H. Prochaska, Natalie Arnold, Karl J. Lackner, Tommaso Gori, Hugo tenCate, Thomas Münzel, Philipp S. Wild, Marina Panova‐Noeva   +13 more
doaj   +1 more source

A comparative study of circulating tumor cell isolation and enumeration technologies in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells were spiked into donor blood to evaluate the recovery rates of the following circulating tumor cell (CTC) enrichment technologies: CellMag™, EasySep™, RosetteSep™, Parsortix® PR1, and Parsortix® Prototype systems. Each method's advantages and disadvantages are described.
Volga M Saini, Ezgi Oner, Mark P. Ward, Sinead Hurley, Brian David Henderson, Faye Lewis, Stephen P. Finn, Gerard J. Fitzmaurice, John J. O'Leary, Sharon O'Toole, Lorraine O'Driscoll, Kathy Gately   +11 more
wiley   +1 more source

Purpose and criteria for blood smear scan, blood smear examination, and blood smear review. [PDF]

, 2012
A microscopic examination of an appropriately prepared and well-stained blood smear by a knowledgeable laboratory professional is necessary and clinically useful in a number of circumstances and for a variety of reasons.
Florea, Alina Dulau, Gong, Jerald, Gulati, Gene, Song, Jinming   +3 more
core   +2 more sources

Leukocyte Classification using Multimodal Architecture Enhanced by Knowledge Distillation [PDF]

arXiv, 2022
Recently, a lot of automated white blood cells (WBC) or leukocyte classification techniques have been developed. However, all of these methods only utilize a single modality microscopic image i.e. either blood smear or fluorescence based, thus missing the potential of a better learning from multimodal images.
arxiv  

A prospective study on reliability and effectiveness of different hematological parameters for early diagnosis of neonatal sepsis in a tertiary care hospital of sub-Himalayan region

Asian Journal of Medical Sciences, 2022
Background: Neonatal sepsis is a major cause of morbidity and mortality in newborn.Early diagnosis of neonatal sepsis is the top priority to all clinicians for early initiation of appropriate treatment which will reduce the morbidity and mortality in ...
Nilay Ranjan Bagchi
doaj   +1 more source

Integrative analysis of circulating tumor cells (CTCs) and exosomes from small‐cell lung cancer (SCLC) patients: a comprehensive approach

Molecular Oncology, EarlyView.
This study simultaneously investigated circulating tumor cells (CTCs) and exosomes from small‐cell lung cancer (SCLC) patients. The elevated expression of JUNB and CXCR4 in CTCs was a poor prognostic factor for SCLC patients, whereas exosomal overexpression of these biomarkers revealed a high discrimination ability of patients from healthy individuals,
Dimitrios Papakonstantinou, Argyro Roumeliotou, Evangelia Pantazaka, Athanasios‐Nasir Shaukat, Athina Christopoulou, Angelos Koutras, Foteinos‐Ioannis Dimitrakopoulos, Vassilis Georgoulias, Anastasia Xagara, Evangelia Chantzara, Fillipos Koinis, Athanasios Kotsakis, Constantinos Stathopoulos, Galatea Kallergi   +13 more
wiley   +1 more source

Selection for leukocyte counts in mice

Genetical Research, 1966
By directional selection for total leukocyte counts from a hybrid mouse stock we have gradually established two lines of mice, LLC (Low Leukocyte Count) and HLC (High Leukocyte Count), which differ both in total and in differential leukocyte counts. A randombred line (RLC) is also being concurrently maintained.
openaire   +3 more sources

Complex Dynamics of a Bilamellar Vesicle as a Simple Model for Leukocytes [PDF]

, 2012
The influence of the internal structure of a biological cell (e.g., a leukocyte) on its dynamics and rheology is not yet fully understood. By using 2D numerical simulations of a bilamellar vesicle (BLV) consisting of two vesicles as a cell model, we find that increasing the size of the inner vesicle (mimicking the nucleus) triggers a tank-treading-to ...
arxiv   +1 more source

The accumulation of myeloid‐derived suppressor cells participates in abdominal infection‐induced tumor progression through the PD‐L1/PD‐1 axis

Molecular Oncology, EarlyView.
This study explores how sepsis affects GC progression by creating an immunosuppressive environment. Our findings reveal that sepsis promotes immune dysregulation, enhancing tumor growth and metastasis. Targeting the PD‐1/PD‐L1 pathway with monoclonal antibodies shows potential for restoring immune function and improving outcomes in cancer patients ...
Yiding Wang, Ting Guo, Xiaofang Xing, Xijuan Liu, Xuejun Gan, Yingai Li, Yan Liu, Fei Shan, Zhouqiao Wu, Jiafu Ji, Ziyu Li   +10 more
wiley   +1 more source