Results 101 to 110 of about 1,708,388 (381)
Molecular Oncology, EarlyView.Patient‐derived xenografts (PDXs) can be improved by implantation of a humanized niche. We tested different biomaterials and approaches, and demonstrate that the combination of an injectable biomaterial for scaffold creation plus an intravenous route for acute myeloid leukemia (AML) xenotransplantation provide the most convenient and robust approach to
Daniel Busa +13 more
wiley +1 more source
Effects of Feeding Bt Maize to Sows during Gestation and Lactation on Maternal and Offspring Immunity and Fate of Transgenic Material [PDF]
, 2012 peer-reviewedBackground: We aimed to determine the effect of feeding transgenic maize to sows during gestation and lactation on maternal and offspring immunity and to assess the fate of transgenic material.
Buzoianu, Stefan G. +10 more
core +2 more sources
Towards Interpretable Classification of Leukocytes based on Deep Learning [PDF]
arXiv, 2023 Label-free approaches are attractive in cytological imaging due to their flexibility and cost efficiency. They are supported by machine learning methods, which, despite the lack of labeling and the associated lower contrast, can classify cells with high accuracy where the human observer has little chance to discriminate cells.
arxiv
Multiple barriers in forced rupture of protein complexes [PDF]
J. Chem. Phys. (2012) vol. 137, 055103, 2012 Curvatures in the most probable rupture force ($f^*$) versus log-loading rate ($\log{r_f}$) observed in dynamic force spectroscopy (DFS) on biomolecular complexes are interpreted using a one-dimensional free energy profile with multiple barriers or a single barrier with force-dependent transition state.
arxiv +1 more source
Predictive value of lymphocytopenia and the neutrophil-lymphocyte count ratio for severe imported malaria [PDF]
, 2013 Background: Lymphocytopenia has frequently been described in patients with malaria, but studies on its association with disease severity have yielded conflicting results. The neutrophil/lymphocyte count ratio (NLCR) has been introduced as a parameter for
De Mendonça Melo, M. (Mariana) +7 more
core +1 more source
Clinical significance of stratifying prostate cancer patients through specific circulating genes
Molecular Oncology, EarlyView.We tested a specific panel of genes representative of luminal, neuroendocrine and stem‐like cells in the blood of prostate cancer patients, showing predictive value from diagnosis to late stages of disease. This approach allows monitoring of treatment responses and outcomes at specific time points in trajectories.
Seta Derderian +12 more
wiley +1 more source
Artificial Intelligence Enabled Reagent-free Imaging Hematology Analyzer [PDF]
arXiv, 2020 Leukocyte differential test is a widely performed clinical procedure for screening infectious diseases. Existing hematology analyzers require labor-intensive work and a panel of expensive reagents. Here we report an artificial-intelligence enabled reagent-free imaging hematology analyzer (AIRFIHA) modality that can accurately classify subpopulations of
arxiv
Mechanism of margination in confined flows of blood and other multicomponent suspensions [PDF]
Physical Review Letters, 109, 108102, 2012, 2012 Flowing blood displays a phenomenon called margination, in which leukocytes and platelets are preferentially found near blood vessel walls, while erythrocytes are depleted from these regions. Here margination is investigated using direct hydrodynamic simulations of a binary suspension of stiff (s) and floppy (f) capsules, as well as a stochastic model ...
arxiv +1 more source
Molecular Oncology, EarlyView.MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin +14 more
wiley +1 more source
Gambaran Hitung Leukosit Pre Operatif Pada Tiap-tiap Tingkat Keparahan Apendisitis Akut Anak (Berdasarkan Klasifikasi Cloud) Di RSUD Arifin Achmad Provinsi Riau Periode Januari 2011-desember 2012 [PDF]
, 2014 Pediatric acute appendicitis is surgical case which one of diagnosis component islaboratory test. The leukocyte count is one of the most common laboratory tests usedbecause leukocyte count increased approximately 70% in children with acuteappendicitis ...
Arbi, I. (Inzta) +2 more
core