Results 141 to 150 of about 190,065 (286)

A Keratinocyte‐Mast Cell NF‐κB2/CXCL2/IL‐6 Amplification Loop Enhances Cutaneous Antifungal Defense Against C. albicans

open access: yesAdvanced Science, EarlyView.
ABSTRACT Mast cells (MCs), key innate immune sentinels at the host–environment interface, serve as primary responders to invading pathogens. However, their specific contribution to host defense against cutaneous Candida albicans (C. albicans) infection and their synergy with other immune and non‐immune cells remain poorly understood. Here, we show that
Yan Yuan   +12 more
wiley   +1 more source

NUDT21 Drives T‐Cell Acute Lymphoblastic Leukemia Through Dual Regulation of Alternative Polyadenylation and Transcriptional Activation

open access: yesAdvanced Science, EarlyView.
In summary, our study defines a coordinated oncogenic model in which NUDT21 integrates alternative polyadenylation–dependent UBE2D3 stabilization and transcriptional activation to sustain MYC‐driven T‐ALL cell survival, thereby establishing NUDT21 as a central regulatory node and a promising therapeutic target.
Conglian Qiu   +18 more
wiley   +1 more source

Diagnostic Value of Combined: C- Reactive Protein, Total Leukocyte Count and Platelet Count in Neonatal Sepsis

open access: yes, 2016
Objective: This study was designed to evaluate the diagnostic value of combination of Total Leukocyte Count, Platelet count and C - reactive protein for the diagnosis of neonatal sepsis.
Hussain Sherazi, Sajid   +1 more
core  

Diagnostic Accuracy of Total Leucocyte Count and Ultrasound in the Diagnosis of Acute Appendicitis

open access: yesJournal of Rawalpindi Medical College, 2012
Background: To compare the diagnostic accuracy of Total Leucocyte Count (TLC) with Ultrasound (USG) abdomen and pelvis in diagnosis of acute appendicitis. Methods: In this cross sectional study 100 patients, with clinical diagnosis of acute appendicitis,
Shehzad Ahmed , Abbasi
doaj  

Synovial fluid pH is as specific as synovial leukocyte count but less sensitive for the diagnosis of chronic prosthetic joint infection. [PDF]

open access: yesJ Orthop Traumatol, 2022
Theil C   +7 more
europepmc   +1 more source

Lymphoid‐Tissue‐on‐Chip Recapitulates Human Antibody Responses In Vitro

open access: yesAdvanced Science, EarlyView.
The presented lymphoid‐tissue‐on‐chip system allows culture of primary human tonsil cells at organotypic high density under perfusion for up to 4 weeks, emulates immune response to soluble vaccines and vaccination via peripheral antigen‐presenting cells and represents a useful tool to assess cellular interactions during homeostasis, immune responses ...
Claudia Teufel   +15 more
wiley   +1 more source

Total Leukocyte Count Depicting the Degree of Inflammation in Acute Appendicitis. [PDF]

open access: yesCureus, 2021
Bilal M   +7 more
europepmc   +1 more source

Liquid Metal Nanotransformers for Drug‐Resistant Pan‐Cancer Therapy in Patient‐Derived Organoids

open access: yesAdvanced Science, EarlyView.
Pan‐cancer therapies are severely limited in drug‐resistance patients due to genetic mutations and other factors, resulting in poor therapeutic outcomes and constrained clinical benefit. Liquid metal nanotransformers, a new class of shape‐transformable nanomaterials capable of dramatic morphological changes, offer a promising physical strategy to ...
Xiaojie Yuan   +19 more
wiley   +1 more source

Four-part leukocyte differential count based on sheathless microflow cytometer and fluorescent dye assay

open access: yes, 2013
Leukocyte differential count is one of the most frequently ordered clinical tests in hospitals. This paper reports a point-of-care test for the leukocyte count by using a microflow cytometer and a fluorescent dye assay.
Shi, Wendian   +3 more
core  

Diagnostic Accuracy Of Total Leukocyte Count, Neutrophil Count, And C-Reactive Protein In The Diagnosis Of Acute Appendititis In Children

open access: yes
Objective: Diagnostic accuracy of total leukocyte count, neutrophil count, and c-reactive protein in the diagnosis of acute appendititis in children Patients and methods: A prospective observational study conducted in the Department of Pediatric Surgery,
Dr. Pooja kumari, Dr. Muhammad arshad, Dr. Chen Wen Li, Dr. Payal bai, ⁠Dr. Fnu Shilpa, ⁠Dr. Aisha bakhtiar
core   +1 more source

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