Results 171 to 180 of about 258,333 (346)

CCL5hi Macrophages Interact with CD8+ T Cells and Potentiate Responsiveness to PD‐1 Blockade Plus Chemotherapy in Esophageal Squamous Cell Carcinoma

open access: yesAdvanced Science, EarlyView.
This study has characterized a functionally distinct macrophage subset, termed CCL5hi macrophages, and elucidated the underlying mechanisms of a regulatory feedback loop that interconnects IFN‐γ, CCL5hi macrophages, and CD8+ T cells within the TME of ESCC undergoing immunochemotherapy.
Yuanzhen Ma   +10 more
wiley   +1 more source

Higher Leukocyte Count Is Associated with Lower Presence of Carotid Lipid-Rich Necrotic Core: A Sub-Study in the Plaque at RISK (PARISK) Study. [PDF]

open access: yesJ Clin Med, 2023
van Velzen TJ   +7 more
europepmc   +1 more source

CRISPR‐MI and scRNA‐Seq Reveal TREM2's Function in Monocyte Infiltration and Macrophage Apoptosis During Abdominal Aortic Aneurysm Development

open access: yesAdvanced Science, EarlyView.
A method is developed for conducting genome‐wide CRISPR/Cas9 screening of monocyte infiltration in vivo (CRISPR‐MI) that is easily adaptable across a variety of disease models. Through the combination of CRISPR‐MI and scRNA‐Seq, this study discovers that Trem2 is a key regulator of early monocyte infiltration in abdominal aortic aneurysm (AAA ...
Haocheng Lu   +30 more
wiley   +1 more source

Diagnostic Accuracy of Total Leucocyte Count and Ultrasound in the Diagnosis of Acute Appendicitis

open access: yesJournal of Rawalpindi Medical College, 2012
Background: To compare the diagnostic accuracy of Total Leucocyte Count (TLC) with Ultrasound (USG) abdomen and pelvis in diagnosis of acute appendicitis. Methods: In this cross sectional study 100 patients, with clinical diagnosis of acute appendicitis,
Shehzad Ahmed , Abbasi
doaj  

Total Leukocyte Count Depicting the Degree of Inflammation in Acute Appendicitis. [PDF]

open access: yesCureus, 2021
Bilal M   +7 more
europepmc   +1 more source

Multiomics Analyses Reveal an Essential Role of Tryptophan in Treatment of csDMARDs in Rheumatoid Arthritis

open access: yesAdvanced Science, EarlyView.
Rheumatoid arthritis is a disease characterized by joint inflammation. Approximately 50% of patients show insufficient response to traditional synthetic disease‐modifying antirheumatic drugs. This study aims to elucidate differential molecular profiles of the mechanisms underlying drug responses through multi‐omics strategy.
Congcong Jian   +26 more
wiley   +1 more source

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