Results 41 to 50 of about 40,537 (270)

Effect of scaling and root planing on blood counts in patients with chronic generalized periodontitis

Indian Journal of Dental Sciences, 2017
Background: Many systemic diseases have been implicated as risk factors in periodontal disease. Studies suggest that periodontal infection can adversely affect systemic health; by inference periodontal disease will also have an effect on blood values ...
Devinder Singh Kalsi, Anchal Sood, Simran Mundi, Vikrant Sharma   +3 more
doaj   +1 more source

Clinical applications of next‐generation sequencing‐based ctDNA analyses in breast cancer: defining treatment targets and dynamic changes during disease progression

Molecular Oncology, EarlyView.
Circulating tumor DNA (ctDNA) offers a possibility for different applications in early and late stage breast cancer management. In early breast cancer tumor informed approaches are increasingly used for detecting molecular residual disease (MRD) and early recurrence. In advanced stage, ctDNA provides a possibility for monitoring disease progression and
Eva Valentina Klocker, Samantha Hasenleithner, Rupert Bartsch, Simon P. Gampenrieder, Daniel Egle, Christian F. Singer, Gabriel Rinnerthaler, Michael Hubalek, Katja Schmitz, Zsuzsanna Bago‐Horvath, Andreas Petzer, Sonja Heibl, Ellen Heitzer, Marija Balic, Michael Gnant   +14 more
wiley   +1 more source

CoTCoNet: An Optimized Coupled Transformer-Convolutional Network with an Adaptive Graph Reconstruction for Leukemia Detection [PDF]

Computers in Biology and Medicine 179C (2024) 108821
Swift and accurate blood smear analysis is an effective diagnostic method for leukemia and other hematological malignancies. However, manual leukocyte count and morphological evaluation using a microscope is time-consuming and prone to errors. Conventional image processing methods also exhibit limitations in differentiating cells due to the visual ...
arxiv   +1 more source

Circulating tumor cells in metastatic breast cancer patients treated with immune checkpoint inhibitors – a biomarker analysis of the ALICE and ICON trials

Molecular Oncology, EarlyView.
In this explorative biomarker analysis, we assessed serial sampling of circulating tumor cells (CTCs) with CellSearch in two randomized trials testing immune checkpoint inhibitors (ICIs) in metastatic breast cancer. Our data demonstrate a prognostic potential of CTCs, most apparent 4 weeks into ICI therapy.
Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Elin Borgen, Cecilie Bendigtsen Schirmer, Bjørnar Gilje, Øystein Garred, Jon Lømo, Marius Stensland, Oddmund Nordgård, Ragnhild Sørum Falk, Randi R. Mathiesen, Hege G. Russnes, Jon Amund Kyte, Bjørn Naume   +13 more
wiley   +1 more source

The impact of platelet indices on clinical outcome in heart failure: results from the MyoVasc study

ESC Heart Failure, 2021
Aims Platelet indices have been associated with traditional cardiovascular risk factors, cardiovascular diseases and all‐cause mortality. This study aimed to investigate the role of platelet count, mean platelet volume (MPV) and platelet‐to‐leukocyte ...
Bianca Dahlen, Andreas Schulz, Sebastian Göbel, Sven‐Oliver Tröbs, Sören Schwuchow‐Thonke, Henri M. Spronk, Jürgen H. Prochaska, Natalie Arnold, Karl J. Lackner, Tommaso Gori, Hugo tenCate, Thomas Münzel, Philipp S. Wild, Marina Panova‐Noeva   +13 more
doaj   +1 more source

L-selectin mediated leukocyte tethering in shear flow is controlled by multiple contacts and cytoskeletal anchorage facilitating fast rebinding events [PDF]

PNAS 101: 6940-6945 (2004), 2005
L-selectin mediated tethers result in leukocyte rolling only above a threshold in shear. Here we present biophysical modeling based on recently published data from flow chamber experiments (Dwir et al., J. Cell Biol. 163: 649-659, 2003) which supports the interpretation that L-selectin mediated tethers below the shear threshold correspond to single L ...
arxiv   +1 more source

A comparative study of circulating tumor cell isolation and enumeration technologies in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells were spiked into donor blood to evaluate the recovery rates of the following circulating tumor cell (CTC) enrichment technologies: CellMag™, EasySep™, RosetteSep™, Parsortix® PR1, and Parsortix® Prototype systems. Each method's advantages and disadvantages are described.
Volga M Saini, Ezgi Oner, Mark P. Ward, Sinead Hurley, Brian David Henderson, Faye Lewis, Stephen P. Finn, Gerard J. Fitzmaurice, John J. O'Leary, Sharon O'Toole, Lorraine O'Driscoll, Kathy Gately   +11 more
wiley   +1 more source

Leukocyte Count in Solid Organ Transplant Recipients After SARS-CoV-2 mRNA Vaccination and Infection

Vaccines
Background: Solid organ transplant (SOT) recipients are at risk of severe COVID-19. Vaccination is an important preventive measure but may have side effects, including decreased leukocyte counts. We aimed to describe the prevalence and relative incidence
Marita Kern, Sebastian Rask Hamm, Christian Ross Pedersen, Dina Leth Møller, Josefine Amalie Loft, Rasmus Bo Hasselbalch, Line Dam Heftdal, Mia Marie Pries-Heje, Michael Perch, Søren Schwartz Sørensen, Allan Rasmussen, Peter Garred, Kasper Karmark Iversen, Henning Bundgaard, Caroline A. Sabin, Susanne Dam Nielsen   +15 more
doaj   +1 more source

A prospective study on reliability and effectiveness of different hematological parameters for early diagnosis of neonatal sepsis in a tertiary care hospital of sub-Himalayan region

Asian Journal of Medical Sciences, 2022
Background: Neonatal sepsis is a major cause of morbidity and mortality in newborn.Early diagnosis of neonatal sepsis is the top priority to all clinicians for early initiation of appropriate treatment which will reduce the morbidity and mortality in ...
Nilay Ranjan Bagchi
doaj   +1 more source

Integrative analysis of circulating tumor cells (CTCs) and exosomes from small‐cell lung cancer (SCLC) patients: a comprehensive approach

Molecular Oncology, EarlyView.
This study simultaneously investigated circulating tumor cells (CTCs) and exosomes from small‐cell lung cancer (SCLC) patients. The elevated expression of JUNB and CXCR4 in CTCs was a poor prognostic factor for SCLC patients, whereas exosomal overexpression of these biomarkers revealed a high discrimination ability of patients from healthy individuals,
Dimitrios Papakonstantinou, Argyro Roumeliotou, Evangelia Pantazaka, Athanasios‐Nasir Shaukat, Athina Christopoulou, Angelos Koutras, Foteinos‐Ioannis Dimitrakopoulos, Vassilis Georgoulias, Anastasia Xagara, Evangelia Chantzara, Fillipos Koinis, Athanasios Kotsakis, Constantinos Stathopoulos, Galatea Kallergi   +13 more
wiley   +1 more source