Results 91 to 100 of about 248,987 (332)

Platelets and galectins [PDF]

, 2014
A major function of platelets is keeping the vascular system intact. Platelet activation at sites of vascular injury leads to the formation of a hemostatic plug.
Schattner, Mirta Ana
core   +1 more source

Advances in Bioprinting to Model Immune‐Mediated Skin Diseases

Advanced Healthcare Materials, EarlyView.
This review explores how 3D bioprinting drives innovation in developing in vitro skin models that mimic immune‐mediated diseases. It highlights current technologies, key applications in studying skin pathologies, and emerging challenges. The review points toward future opportunities for improving disease modeling and advancing therapeutic and cosmetic ...
Andrea Ulloa‐Fernández, Marica Markovic, Julia Fernández‐Pérez, Georg Stary, Aleksandr Ovsianikov   +4 more
wiley   +1 more source

ESTIMATION OF LEVEL OF SUBPOPULATION CD14⁺/CD16⁺ MONOCYTES IN PATIENTS WITH JUVENILE DEPRESSIONS

Медицинская иммунология, 2019
At present, at least two phenotypically different subpopulations of blood monocytes have been identified: "classical" monocytes with the phenotype CD14++/CD16-  and "nonclassical" (pro-inflammatory) with the phenotype CD14+/CD16+. It has been established
E. F. Vasilyeva, T. P. Sekirina, Z. V. Sarmanova, S. A. Zozulya, M. A. Omel'chenko, T. P. Klushnik   +5 more
doaj   +1 more source

Analysis of the pathogenic factors and management of dry eye in ocular surface disorders [PDF]

, 2017
The tear film represents the interface between the eye and the environment. The alteration of the delicate balance that regulates the secretion and distribution of the tear film determines the dry eye (DE) syndrome. Despite having a multifactorial origin,
Albietz, Alio, Ambrosio, Djalilian, Dogru, Li, Nebbioso, Nebbioso, Patel, Rajan, Solomon, Suzuki, Toda, Wilson, Zhu   +14 more
core   +1 more source

Mesenchymal Stem Cell‐Derived Apoptotic Micro‐Vesicles Repaired Sciatic Nerve Defect by Regulating Early Inflammatory Microenvironment and Promoting Angiogenesis

Advanced Healthcare Materials, EarlyView.
HUCMSC‐Apo‐mvs enhance peripheral nerve repair by modulating the inflammatory microenvironment (IME), primarily through coordinated actions on three functional cells. They recruit macrophages and promote their polarization from pro‐inflammatory M1 to anti‐inflammatory M2 phenotypes, increasing secretion of IL‐10 and VEGF.
Haolin Liu, Yiben Ouyang, Bo Wang, Xiaochun Zhang, Yanjun Guan, Ruichao He, Yuhui Cui, Junli Wang, Qianru Yao, Yixiao Tan, Xiwei Peng, Xing Xiong, Sice Wang, Dongdong Li, Haofeng Cheng, Tianqi Su, Xiaoyang Fu, Jinjuan Zhao, Mingqian Yu, Yi Wang, Jiang Peng, Yu Wang   +21 more
wiley   +1 more source

Macrophage-derived human resistin is induced in multiple helminth infections and promotes inflammatory monocytes and increased parasite burden. [PDF]

, 2015
Parasitic helminth infections can be associated with lifelong morbidity such as immune-mediated organ failure. A better understanding of the host immune response to helminths could provide new avenues to promote parasite clearance and/or alleviate ...
A Tarkowski, AL Moncayo, AM Gan, B Min, Cathy Steel, CH Kuo, CM Steppan, D Artis, D Voehringer, DD Taub, DR Herbert, DR Herbert, DR Neill, Edward J. Pearce, F Chen, Gang Chen, GD Thomas, Graham Le Gros, H Helmby, HK Park, HS Jung, J Bethony, J Urban, J Wang, JA Jackson, Jessica C. Jang, JF Urban Jr, JI Odegaard, JJ Reece, Josiah I. Chung, JT Pesce, K Migita, KT Cuenco, L Boring, L Le Goff, L Patel, LC Osborne, M Lehrke, M Lehrke, M Qatanani, Mali Camberis, Mark A. Barnes, Meera G. Nair, MG Nair, MG Nair, MG Nair, Mitchell A. Lazar, MM Pirvulescu, MP Reilly, N Silswal, P Loke, PF Weller, Philip J. Cooper, PJ George, PJ Hotez, R Anuradha, RM Anthony, RT Semnani, RZ Yang, S Babu, S Babu, S Babu, S Babu, S Jiang, S Lee, Spencer H. Wang, Thomas B. Nutman, TT MacDonald, W He, Y Benomar, YY Hsieh   +70 more
core   +5 more sources

Microneedle Technology in Psoriasis Management: Mechanistic Insights, Technological Innovation, Clinical Progress, and Challenges

Advanced Healthcare Materials, EarlyView.
This review explores the evolving role of microneedle systems in psoriasis management, highlighting their potential for enhanced drug delivery, diagnosis, and disease monitoring. It also discusses unmet clinical needs for psoriasis management and technical challenges, while outlining strategic directions to advance microneedle integration into routine ...
Fatma Moawad, Yasmine Ruel, Roxane Pouliot, Davide Brambilla   +3 more
wiley   +1 more source

Editorial: NK cell defects: diagnosis and treatment

Frontiers in Immunology, 2023
Snehal Shabrish, Snehal Shabrish, Shanmuganathan Chandrakasan, Manisha Madkaikar   +3 more
doaj   +1 more source

Pro-Inflammatory Chemokines and Cytokines Dominate the Blister Fluid Molecular Signature in Patients with Epidermolysis Bullosa and Affect Leukocyte and Stem Cell Migration. [PDF]

, 2017
Hereditary epidermolysis bullosa (EB) is associated with skin blistering and the development of chronic nonhealing wounds. Although clinical studies have shown that cell-based therapies improve wound healing, the recruitment of therapeutic cells to ...
Alexeev, Vitali, Fortuna, Giulio, Igoucheva, Olga, Mukhtarzada, Lila, Palisson, Francis, Salas-Alanis, Julio Cesar, South, Andrew P., Uitto, Jouni   +7 more
core   +1 more source

Evidence linking exposure of fish primary macrophages to antibiotics activates the NF-kB pathway. [PDF]

, 2020
Low doses of antibiotics are ubiquitous in the marine environment and may exert negative effects on non-target aquatic organisms. Using primary macrophages of common carp, we investigated the mechanisms of action following exposure to several common ...
Chen, Qiqing, Fang, Meijuan, Greer, Justin, Hu, Jiaqi, Magnuson, Jason T, Qiu, Wenhui, Schlenk, Daniel, Yang, Ming, Zheng, Chunmiao   +8 more
core