Results 171 to 180 of about 245,088 (289)

Pseudoathetotic Pseudodystonia as a Manifestation of Isolated Medullary Demyelination in Neuromyelitis Optica Spectrum Disorder. [PDF]

Tremor Other Hyperkinet Mov (N Y)
Mohapatra P, Hema LS, Mahadevan A, Garg D, Agarwal A, Pandit AK, Garg A, Srivastava AK, Radhakrishnan DM.   +8 more
europepmc   +1 more source

Integrative Analyses Identify a cGAS‐STING Pathway‐Driven Signature With Context‐Dependent Roles in Systemic Lupus Erythematosus

Advanced Science, EarlyView.
Zhang et al. identify M7core, a critical cGAS‐STING pathway‐driven gene signature that is activated in most lupus patients’ blood and links to lupus disease severity, lymphopenia, and lupus nephritis. They further reveal the diagnostic and pathogenic characteristics of M7core and emphasize the importance of assessing pathway activity before initiating ...
Lele Zhang, Ming‐Ju Amy Lyu, Ze Hong, Jing Sun, Lan Guo, Jiameng Hu, Munire Maimaiti, Chenhui Li, Jinyi Song, Xiang Zhang, Huansha Yu, Chen Wang, Xuan Wang, Haiyang Hu   +13 more
wiley   +1 more source

Ameliorating Effect of <i>Lavandula Angustifolia</i> on Experimental Autoimmune Encephalomyelitis Symptoms by Modulation of Immune Responses. [PDF]

Adv Biomed Res
Mahmoodi M, Jafarzadeh A, Aghaei A, Ramezani M, Zainodini N, Sedghy F, Pouya F.   +6 more
europepmc   +1 more source

Leukocyte Alkaline Phosphatase in Hematological Disorders

Leukocyte Alkaline Phosphatase in Hematological Disorders
Leukocyte alkaline phosphatase activity was studied biochemically and histochemically in various blood diseases. 1) N-APA is preferable to LAPA as a unit of biochemical measurement. 2) The low content of leukocyte AP in CGL was confirmed. The determination of leukocyte AP is useful in the diagnosis and treatment of CGL. 3) The low N-APA in CGL rises to
openaire  

Dendritic Nano‐Based Slippery Coating by Synergistic Mechanical and Electrostatic Interactions with Persistent and Exceptional Combats Thrombosis

Advanced Science, EarlyView.
A novel dendritic nano‐based slippery coating (DNSC), fabricated by encapsulating carboxyl silicone oil within amino dendritic silica nanoparticles and co‐embedding them in an epoxy resin matrix. The dendritic architecture enhances nanoparticle dispersion in the matrix and establishes mechanical interlock.
Shu Zhang, Yao Shen, Juan Liu, Qing Zeng, Yunze Ma, Shuping Chen, Taiyu Nan, Xiaoying Qiu, Jiayi Yu, Tao Fan, Guozhi Huang, Jihua Zou, Chengduan Yang   +12 more
wiley   +1 more source

Editorial: Community series in innate immunity: platelets and their interaction with other cellular elements in host defense and disease pathogenesis, volume II. [PDF]

Front Immunol
Kannan M, Ahmad F, Shankar EM.
europepmc   +1 more source

Loss of VMP1 Impairs Tight Junction Recycling and Aggravates Intestinal Barrier Dysfunction in Inflammatory Bowel Disease

Advanced Science, EarlyView.
This study identifies vacuole membrane protein 1 (VMP1) as a critical regulator of intestinal epithelial barrier homeostasis. VMP1 facilitates the recruitment of CORO1C to late endosomes, supporting Retromer‐mediated recycling of the tight junction protein Occludin.
Jiawei Zhao, Jianjun Zou, Chen Zhou, Yingui Wang, Yiman Liu, Yanqing Zhou, Yuxiang Wang, Xinyu Zhang, Huishu Yang, Hongjie Yin, Dongsheng Bai, Yue Zhao, Na Lu   +12 more
wiley   +1 more source

A case of celiac disease carrying the half DQ2 variant with a variety of psychiatric manifestations. [PDF]

PCN Rep
Sato A, Kunii Y, Tsunoda T, Yamaguchi Y, Osonoe K, Hoshino S.   +5 more
europepmc   +1 more source

Leveraging Artificial Intelligence and Large Language Models for Cancer Immunotherapy

Advanced Science, EarlyView.
Cancer immunotherapy faces challenges in predicting treatment responses and understanding resistance mechanisms. Artificial intelligence (AI) and machine learning (ML) offer powerful solutions for cancer immunotherapy in patient stratification, biomarker discovery, treatment strategy optimization, and foundation model development.
Xinchao Wu, Mengtao Sun, Lusheng Li, Jieqiong Wang, Shibiao Wan   +4 more
wiley   +1 more source

Nanoparticle‐Mediated Immunometabolic‐Epigenetic Remodeling Enhances Schwann Cell‐Macrophage Interaction for Sciatic Nerve Regeneration

Advanced Science, EarlyView.
A biomimetic Prussian White nanoparticle (PW) is engineered to achieve long‐term local retention and orchestrate immunometabolic‐epigenetic remodeling for sciatic nerve regeneration. PW directly targets hexokinase 2 to suppress glycolysis, thereby elevating α‐ketoglutarate and driving Kdm4a/b‐mediated demethylation of H3K9me3.
Wenying Xu, Rongrong Wu, Zhicheng Liu, Hongyu Yan, Huan Zhang, Yuanyi Zheng, Xiaojun Cai   +6 more
wiley   +1 more source