Leukostasis by hyperleukocytic childhood acute leukemia: pathophysiology, clinical presentation, and emergency care [PDF]
Pediatric Emergency Medicine Journal, 2019 Hyperleukocytosis (HL), defined by a peripheral white blood cell (WBC) count exceeding 100,000/mm3, is occasionally observed in childhood acute leukemia.
Ki Lyong Nam +2 more
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Indian Pediatrics Case Reports, 2023 Background: Although physiological leukocytosis is known in premature neonates, hyperleukocytosis (total leukocyte count more than 100 × 103 /μL) is rarely seen.
Mathews E Kuriakose +2 more
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Local oxidative and nitrosative stress increases in the microcirculation during leukocytes-endothelial cell interactions. [PDF]
PLoS ONE, 2012 Leukocyte-endothelial cell interactions and leukocyte activation are important factors for vascular diseases including nephropathy, retinopathy and angiopathy.
Saptarshi Kar, Mahendra Kavdia
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Changes in Circadian Rhythms Dysregulate Inflammation in Ageing: Focus on Leukocyte Trafficking
Frontiers in Immunology, 2021 Leukocyte trafficking shows strong diurnal rhythmicity and is tightly regulated by circadian rhythms. As we age, leukocyte trafficking becomes dysregulated, contributing to the increased systemic, low-grade, chronic inflammation observed in older adults.
Poppy Nathan +3 more
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Platelet-leukocyte interactions: immunoregulatory role and pathophysiological relevance
Медицинская иммунология, 2022 Blood platelets are the central players in thrombosis and blood coagulation. Moreover, they also exhibit immunoregulatory properties and bridge hemostasis and immunity.
O. V. Pavlov +3 more
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Brain, Behavior, & Immunity - Health, 2022 Reduced awareness of neuropsychological disorders (i.e., anosognosia) is a striking symptom of post-COVID-19 condition. Some leukocyte markers in the acute phase may predict the presence of anosognosia in the chronic phase, but they have not yet been ...
A. Nuber-Champier +7 more
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Anxiety: An overlooked confounder in the characterisation of chronic stress-related conditions?
PLoS ONE, 2020 Although anxiety disorders are among the most prevalent of psychiatric disorders, childhood trauma-related studies seldom consider anxiety proneness as distinct aetiological contributor.
Monet Viljoen +5 more
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Traumatic Brain Injury Induces Genome-Wide Transcriptomic, Methylomic, and Network Perturbations in Brain and Blood Predicting Neurological Disorders. [PDF]
, 2017 The complexity of the traumatic brain injury (TBI) pathology, particularly concussive injury, is a serious obstacle for diagnosis, treatment, and long-term prognosis. Here we utilize modern systems biology in a rodent model of concussive injury to gain a
Agrawal, Rahul +5 more
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Frontiers in Immunology, 2022 BackgroundTelomere length (TL) has been recognized to be fundamental to the risk of autoimmune disorders. However, the role of leukocyte TL in Graves’ disease has not yet been fully elucidated.
Meijie Ye, Yu Wang, Yiqiang Zhan
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Telomere length as a predictor of response to Pioglitazone in patients with unremitted depression: a preliminary study. [PDF]
, 2016 We studied peripheral leukocyte telomere length (LTL) as a predictor of antidepressant response to PPAR-γ agonist in patients with unremitted depression.
Blackburn, E +4 more
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