Results 21 to 30 of about 245,088 (289)

TLR7-mediated skin inflammation remotely triggers chemokine expression and leukocyte accumulation in the brain [PDF]

, 2016
Background: The relationship between the brain and the immune system has become increasingly topical as, although it is immune-specialised, the CNS is not free from the influences of the immune system.
A Boivin, A Constant, A Walter, AD Bachstetter, Alison McColl, B Winner, BT Fife, C Callewaere, C D'Mello, C Gemma, CA Thomson, Carolyn A. Thomson, CP Marques, CS McKimmie, CT Ekdahl, D Michlmayr, D Michlmayr, EE Ubogu, G Banisadr, G Banisadr, Gerard J. Graham, JH Dufour, JL Teeling, Jonathan Cavanagh, JS Cameron, JS Snyder, JT Rogers, L Azzi, L Cartier, L Fits van der, Louis Nerurkar, M Baggiolini, M Udina, ML Monje, MM Lee, N Andrews, Q Liu, R Dantzer, R Deacon, R Krishnan, R Rola, RM Deacon, RM Ransohoff, S Baraldi, S Goethals, S Potvin, S Tyring, SM O'Brien, U Patel, U Puntener, W Huang da, W Huang da, W Rostene, WJ Karpus   +53 more
core   +2 more sources

Adjusting MtDNA Quantification in Whole Blood for Peripheral Blood Platelet and Leukocyte Counts. [PDF]

PLoS ONE, 2016
Alterations of mitochondrial DNA copy number (mtDNAcn) in the blood (mitochondrial to nuclear DNA ratio) appear associated with several systemic diseases, including primary mitochondrial disorders, carcinogenesis, and hematologic diseases.
Yamilee Hurtado-Roca, Marta Ledesma, Monica Gonzalez-Lazaro, Raquel Moreno-Loshuertos, Patricio Fernandez-Silva, Jose Antonio Enriquez, Martin Laclaustra   +6 more
doaj   +1 more source

Large-scale associations between the leukocyte transcriptome and BOLD responses to speech differ in autism early language outcome subtypes. [PDF]

, 2018
Heterogeneity in early language development in autism spectrum disorder (ASD) is clinically important and may reflect neurobiologically distinct subtypes.
A Battle, A Krishnan, A Perry, A Schroeder, A Sugathan, A Venter, AJ Willsey, AM Wetherby, AR McIntosh, AR Pfenning, AT Hilliard, BS Abrahams, C Demopoulos, C Lord, CR Genovese, Cynthia Carter Barnes, DA Rossignol, DH Geschwind, DH Geschwind, DL Vargas, E Redcay, E Redcay, EA Boyle, EJ Greenblatt, Eric Courchesne, F Happé, G Dehaene-Lambertz, G Hickok, G Konopka, G Konopka, H Tager-Flusberg, HR Cremers, I Voineagu, J Cotney, JA Kosmicki, JA Miller, JC Darnell, JD Storey, JI Berman, JT Morgan, K Gotham, K Pierce, K Pierce, K Pierce, Karen Pierce, L Hippolyte, Linda Lopez, Lisa Eyler, LT Eyler, M Chikina, M Lek, MC Lai, MC Oldham, MCN Marchetto, ME Ritchie, Michael V. Lombardo, MM Kjelgaard, MV Lombardo, Nathan E. Lewis, NN Parikshak, NN Parikshak, NR Wray, P Du, P Howlin, P Langfelder, P Langfelder, P Szatmari, R Bernier, RC Gentleman, Richard A. I. Bethlehem, RJ Kelleher III, S Kapur, S Rubeis De, S Sandin, SJ Sanders, T Pramparo, T Pramparo, T Yarkoni, Tiziano Pramparo, Vahid Gazestani, Varun Warrier, X Liu, X Nuttle   +82 more
core   +1 more source

Shining a Light on Intestinal Traffic

Clinical and Developmental Immunology, 2012
Inflammatory bowel disease (IBD), encompassing Crohn's disease and ulcerative colitis, is associated with enhanced leukocyte infiltration to the gut, which is directly linked to the clinical aspects of these disorders.
Carola T. Murphy, Kenneth Nally, Fergus Shanahan, Silvia Melgar   +3 more
doaj   +1 more source

Platelet volume variation in major psychiatric disorders

Psychiatry and Clinical Psychopharmacology, 2021
Objective: Mean platelet volume (MPV) is one of the indicators of platelet function. Changes in platelet function have been reported in many psychiatric disorders.
Murat Ilhan Atagun, Sukru Alperen Korkmaz, Caglar Soykan, Serdar Suleyman Can, Semra Ulusoy Kaymak, Ali Caykoylu   +5 more
doaj  

Reduction of leukocyte microvascular adherence and preservation of blood-brain barrier function by superoxide-lowering therapies in a piglet model of neonatal asphyxia [PDF]

, 2019
Background: Asphyxia is the most common cause of brain damage in newborns. Substantial evidence indicates that leukocyte recruitment in the cerebral vasculature during asphyxia contributes to this damage. We tested the hypothesis that superoxide radical (
Aarti R. Shah, Aarti R. Shah, Ernesto R. Gonzales, Jacob B. Ruden, Jeffrey M. Gidday, Kevin L. Quick, Laura L. Dugan, Laura L. Dugan, Nan Kennedy, T. S. Park   +9 more
core   +2 more sources

Causal relationships between telomere length and liver disease: a Mendelian randomization study

Frontiers in Genetics, 2023
Background: Leukocyte telomere length and hepatic disorders have been linked in various research studies, although their causative association has not been clarified.
Shuangjing Zhu, Mengtao Yang, Ting Wang, Zhen Ding   +3 more
doaj   +1 more source

Exogenous application of platelet-leukocyte gel during open subacromial decompression contributes to improved patient outcome [PDF]

, 2007
Background: Platelet-leukocyte gel (PLG) is being used during various surgical procedures in an attempt to enhance the healing process. We studied the effects of PLG on postoperative recovery of patients undergoing open subacromial decompression (OSD ...
Devilee, R., Everts, P., Knape, J., Mahoney, C., Oosterbos, C., Stellenboom, M., Van Erp, A., Van Zundert, Adrien   +7 more
core   +2 more sources

Accuracy of leukocyte alkaline phosphatase score to predict JAK2 V617F mutation

Haematologica, 2007
Granulocyte activation parameters have been described in patients with myeloproliferative disorders (MPD). We have evaluated the accuracy of leukocyte alkaline phosphatase (LAP) score to predict JAK2 V617F mutation.
Ana L Basquiera, Fernanda Fassetta, Néstor Soria, José Moreno Barral, Brenda Ricchi, Juan J García   +5 more
doaj   +1 more source

Risk assessment of substance use disorders based on the human leukocyte antigen (HLA)

Scientific Reports, 2023
Substance use disorders (SUDs) are common and costly conditions that are partially attributable to genetic factors. In light of immune system influences on neural and behavioral aspects of addiction, the present study evaluated the influence of genes ...
Lisa M. James, Apostolos P. Georgopoulos
doaj   +1 more source